#AortaEd 🚨
Calcium channel blockers (dihydropyridines benzothiazepines phenylalkylamines) use is associated with ⏫risks of thoracic aortic aneurysm/dissection & abdominal aortic aneurysm in hypertensive👤

UKbio N=140k
13.5 y f/up▶️4327 case

+🐭evidence

#NatComms 2025
www.nature.com/articles/s41...

Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods

Xenium
CosMx 1k
MERSCOPE

Tissue Microarray
17 tumor+16 normal tissue

Transcript count
vs Reference RNAseq
Segmentation accuracy
Cell type annotation

#NatComms 2025
www.nature.com/articles/s41...

People In Isolated Cities Suffer More Violence Against Civilians New study from the Complexity Science Hub and the University of Exeter reveals that city isolation, not size, may drive political violence in Africa.

Cities are often seen as hotbeds of violence, with the assumption that bigger cities are more dangerous. New research by @rafaelprietocuriel.bsky.social ( @csh.ac.at ) and @ronaldomenezes.bsky.social ( @exeter.ac.uk ), published in #NatComms, highlights that 𝐢𝐬𝐨𝐥𝐚𝐭𝐢𝐨𝐧 𝐦𝐚𝐭𝐭𝐞𝐫𝐬.
shorturl.at/ii3jm

Best practices & tools in R & Python for statistical processing and visualization of #Lipidomics & #Metabolomics data

Data imputation/normalization
Batch correction
Data visualization
Statistical models

Instrumental handbook, adoptable for other omics

#NatComms 2025
www.nature.com/articles/s41...

Global increase in the endemism of birds from north to south - Nature Communications Global patterns of endemism (irreplaceability) are still not well known. This study shows that endemism of birds increases from north to south, and highlights the vulnerability of southern hemisphere ...

Global increase in the endemism of birds from north to south #natcomms

www.nature.com/articles/s41...

Improving human papillomavirus vaccination coverage in France: a need to act but not to rush - Nature Communications Suboptimal vaccine uptake is a worldwide public health issue. We need (i) to develop interventional population health research on vaccine uptake and (ii) to ensure better use of the research results b...

Improving human papillomavirus vaccination coverage in France: a need to act but not to rush #natcomms

www.nature.com/articles/s41...

Here an overview of our #translational research on samples from the #NAPHER2 trial recently published in #NatComms @natureportfolio.nature.com. We identified #predictive #biomarkers and molecular dynamics in HER2+ER+ #breastcancer receiving chemo-free #targeted #treatment 👇

Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance - Nature Communications Here they use single nuclei RNA-seq to identify transcripts in skeletal muscle that maintain the neuromuscular junction, both under normal and denervated conditions, which allows them to characterize ...

Congrats to #RueggLab and colleagues on their new #NatComms paper: Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance. #Myoblue tinyurl.com/yeynb3t2

Reproducibility and transparency: what’s going on and how can we help - Nature Communications Problems with experimental reproducibility affect every field of science. However, the opinions on the causes of the reproducibility “crisis” and how we all can help vary amongst fields as well as ind...

Reproducibility and transparency: what’s going on and how can we help #natcomms

www.nature.com/articles/s41...

A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma - Nature Communications Epigenetic causes of intra-tumoural heterogeneity are crucial in paediatric cancers with low mutation rates, such as hepatoblastoma. Here, the authors characterise transcriptional heterogeneity in hep...

Happy to be here & share our work on hepatoblastoma - using transcriptomics and patient-derived tumoroids to identify embryonic biliary transcription factor SOX4 as a modifier of Wnt activation & proliferation - published today in #NatComms @natureportfolio.bsky.social www.nature.com/articles/s41...