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Just said aloud to myself, "I wonder where Oumuamua is right now?" and went over to my laptop.

I think the meds are kicking in.

#noradrenaline #residentalien

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New #RCT showing a prophylactic infusion of #noradrenaline was not superior to rescue #ephedrine at preventing severe hypotension in #cardiacsurgery

www.bjanaesthesia.org/article/S0007-0912(25)00...

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Interested in neuromodulators, especially #norepinephrine / #noradrenaline? Check out this #Naturemethods paper hot off the press from the Patriarchi lab on next-generation NE sensors. It was a pleasure to contribute to this team effort. A genuinely 💡enlightening 💡 advance for monitoring NE in vivo.

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#Noradrenaline #Christmas

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Experimental design and effects on peripheral arousal markers. Top left: Design was within-subject, double-blinded, randomized, and placebo-controlled (Materials and methods). Additionally, the stimulus-response mapping was counterbalanced within participants Bottom: Schematic sequence of events during the spatial contrast discrimination task (Materials and methods). Participants reported the location of the highest contrast Gabor patch (difference in contrast is high for illustration only). Top right: Heart rate and pupil size measured as the average across task blocks (Materials and methods), separately for placebo and atomoxetine sessions. Every connecting line is a participant; large data points in the middle are the group averages.

Experimental design and effects on peripheral arousal markers. Top left: Design was within-subject, double-blinded, randomized, and placebo-controlled (Materials and methods). Additionally, the stimulus-response mapping was counterbalanced within participants Bottom: Schematic sequence of events during the spatial contrast discrimination task (Materials and methods). Participants reported the location of the highest contrast Gabor patch (difference in contrast is high for illustration only). Top right: Heart rate and pupil size measured as the average across task blocks (Materials and methods), separately for placebo and atomoxetine sessions. Every connecting line is a participant; large data points in the middle are the group averages.

How do catecholamines like #noradrenaline influence perceptual #DecisionMaking? @degeelab.bsky.social @donnerlab.bsky.social &co show that higher #catecholamine levels reduce individual choice history biases by dampening bias in the accumulation of sensory evidence @plosbiology.org 🧪 plos.io/4mMmNNX

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Experimental design and effects on peripheral arousal markers. Top left: Design was within-subject, double-blinded, randomized, and placebo-controlled (Materials and methods). Additionally, the stimulus-response mapping was counterbalanced within participants Bottom: Schematic sequence of events during the spatial contrast discrimination task (Materials and methods). Participants reported the location of the highest contrast Gabor patch (difference in contrast is high for illustration only). Top right: Heart rate and pupil size measured as the average across task blocks (Materials and methods), separately for placebo and atomoxetine sessions. Every connecting line is a participant; large data points in the middle are the group averages.

Experimental design and effects on peripheral arousal markers. Top left: Design was within-subject, double-blinded, randomized, and placebo-controlled (Materials and methods). Additionally, the stimulus-response mapping was counterbalanced within participants Bottom: Schematic sequence of events during the spatial contrast discrimination task (Materials and methods). Participants reported the location of the highest contrast Gabor patch (difference in contrast is high for illustration only). Top right: Heart rate and pupil size measured as the average across task blocks (Materials and methods), separately for placebo and atomoxetine sessions. Every connecting line is a participant; large data points in the middle are the group averages.

How do catecholamines like #noradrenaline influence perceptual #DecisionMaking? @degeelab.bsky.social @donnerlab.bsky.social &co show that higher #catecholamine levels reduce individual choice history biases by dampening bias in the accumulation of sensory evidence @plosbiology.org 🧪 plos.io/4mMmNNX

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Experimental design and effects on peripheral arousal markers. Top left: Design was within-subject, double-blinded, randomized, and placebo-controlled (Materials and methods). Additionally, the stimulus-response mapping was counterbalanced within participants Bottom: Schematic sequence of events during the spatial contrast discrimination task (Materials and methods). Participants reported the location of the highest contrast Gabor patch (difference in contrast is high for illustration only). Top right: Heart rate and pupil size measured as the average across task blocks (Materials and methods), separately for placebo and atomoxetine sessions. Every connecting line is a participant; large data points in the middle are the group averages.

Experimental design and effects on peripheral arousal markers. Top left: Design was within-subject, double-blinded, randomized, and placebo-controlled (Materials and methods). Additionally, the stimulus-response mapping was counterbalanced within participants Bottom: Schematic sequence of events during the spatial contrast discrimination task (Materials and methods). Participants reported the location of the highest contrast Gabor patch (difference in contrast is high for illustration only). Top right: Heart rate and pupil size measured as the average across task blocks (Materials and methods), separately for placebo and atomoxetine sessions. Every connecting line is a participant; large data points in the middle are the group averages.

How do catecholamines like #noradrenaline influence perceptual #DecisionMaking? @degeelab.bsky.social @donnerlab.bsky.social &co show that higher #catecholamine levels reduce individual choice history biases by dampening bias in the accumulation of sensory evidence @plosbiology.org 🧪 plos.io/4mMmNNX

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To bolus #noradrenaline or to start an #infusion? Thomsen et al. suggest it makes no difference to post-induction #hypotension in low-risk noncardiac surgery patients. #BJA #GA #norepinephrine

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Valerie Y. H. van Weperen of @uclaupdates.bsky.social et al. found that circulating #noradrenaline leads to release of neuropeptide Y from cardiac sympathetic nerve terminals via activation of β-adrenergic receptors 🔃 🫀

📜 Read the #Research: buff.ly/lBumjAv

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Research on neuronal plasticity in the #respiratory control system reports triggering of #hypoglossal long-term facilitation (hLTF) by hypoxia-independent stimuli, and newly identifies #noradrenaline from locus coeruleus neurons as triggering hLTF.
doi.org/10.14814/phy...
#Neurophysiology

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Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity How astrocytes regulate neuronal circuits is a fundamental, unsolved question in neurobiology. Nevertheless, few studies have explored the rules that govern when astrocytes respond to different neurot...

Fantastic talk from the man who made flies sexy - Marc Freeman. Check out this fantastic story on bioRxiv
www.biorxiv.org/content/10.1...

props to Kevin Guttenplan and coauthors!

#noradrenaline #tyramine #astrocytes #neuroscience

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It's official! I've been awarded an #MSCA Postdoctoral Fellowship to work w/ @miriammelis.bsky.social in Cagliari 🏖️🇮🇹

#SPICE-FONTS will investigate the role of my fav neurotransmitter #noradrenaline in neurodevelopmental deficits caused by prenatal #cannabis exposure 🤰🌿

Grateful @ec.europa.eu 🙏🇪🇺

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Anything but small: Microarousals stand at the crossroad between #noradrenaline signaling and key #sleep functions
www.sciencedirect.com/science/arti...

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🚨 Breaking #Physiology news: Spinal arteries dilate in response to #noradrenaline!
Our new study (www.thespinejournalonline.com/article/S152... ) shows increased spinal cord blood flow in-vivo via β-adrenergic receptor–mediated vasodilation, as spinal arteries lack α1-adrenergic receptors.

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How to be consistent with ADHD. Resolve retained reflex syndrome from birth trauma or PTSD, naturally balance brain chemicals. Find out how you can heal: https://buff.ly/4hUme2M

#adhd
#retainedreflexes
#dopamine
#noradrenaline

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