This #STTT review delineates the critical signaling pathways of #NuclearReceptors in human health and disease, discussing the emerging pharmaceutical strategies to modulate these targets for diverse clinical applications.

#OpenAccess: doi.org/10.1038/s413...

Endocrine Examples of Phase Separation in Biology Abstract. Over the past 15 years, groundbreaking discoveries have reshaped our understanding of how biomolecules are organized in space and time within cel

Endocrine Examples of Phase Separation in Biology. Read more in #Endocrinology: bit.ly/48XysUq #NuclearReceptors #SteroidHormoneReceptor #TranscriptionalCondensate @endocrinesociety.bsky.social

Genomic Crosstalk Between Nuclear Receptors in Hormone-dependent Cancers Abstract. Nuclear receptors (NRs) orchestrate transcriptional programs that regulate cell fate decisions, and when these processes are disrupted, they can

Genomic Crosstalk Between Nuclear Receptors in Hormone-dependent Cancers. Read more in #Endocrinology: bit.ly/4aiWdJ5 #NuclearReceptors #Cistrome #Transcriptome @endocrinesociety.bsky.social

A review of #NuclearReceptors, covering their biology, physiological & pathological roles, associated signaling pathways, and emerging therapeutic strategies targeting them. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

It's been a great & productive summer, we had fantastic #undergraduates :) but September is HERE and we are looking for new #POSTDOCS - effective immediately! please spread the word and if interested - let us know! We are into #transcription #inflammation #epigenomics #NuclearReceptors #macrophages

Nuclear receptors in health and disease

A comprehensive review on the physiological & pathological role of #NuclearReceptors (NRs) and related signaling pathways, with highlights on the therapeutics targeting NRs, both clinically and preclinically. #medsky

#STTT #OpenAccess: www.nature.com/articles/s41...

📢 New publication on the Glucocorticoid Receptor IDP domain in collaboration with @alirezamashaghi.bsky.social lab. Always a pleasure to learn from new approaches & techniques. So much still to understand from #nuclearreceptors

This review discusses the #epigenetic alterations of #NuclearReceptors & their impact on various endocrine related diseases and tumors, highlighting current therapies and advances in the development of novel epigenetic targeted therapies. #Diabetes #BreastCancer #medsky


https://buff.ly/aac5qSQ

#NuclearReceptors #Estrogen #NeuroEndo #Endocrinology #Receptors #Alzheimer #AD #Science

📢 We are thrilled to have been selected for an oral presentation at the upcoming ENDO2025 meeting in "my 2nd home" San Francisco! We look forward to showing our new results on #nuclearreceptors and above all meet all the collaborators around the world there ✨️🪇🌎🚀

Home | Adipose Biology Welcome to the inaugural Adipose Biology Conference hosted in Montreal, Canada on August 19th - 20th 2025.

Speaker Spotlight: Carolyn Cummins @carolynlcummins.bsky.social
Join us at #AdiposeBiology Conference in Montreal🇨🇦, Aug 19-20, 2025, to hear from this leader in #nuclearreceptors & #metabolism!
🔗Register: adiposebiology.com

@sablesys.bsky.social @beaudrj.bsky.social @mcgill.ca @uoft.bsky.social

Not #nuclearreceptors

So awesome that Mitch Lazar is visiting Vanderbilt as part of our Apex Lecture Series (scientists who are influencing the trajectory of their fields) to talk about REV-ERB #nuclearreceptors !

In The Pipeline blog featuring estrogen receptor papers with contributions from @nrimpact.bsky.social members @docfanning.bsky.social and @nelsonlab.bsky.social #nuclearreceptors

🎯 Our lab will host on 2025 Josep Ponsetí & Pilar Montanyà to do their TFM @ibub-ub.bsky.social @biologiaub.bsky.social together with Èlia Olivella-Niu @IQSSarrià for her TFG. Glad to have them back to see their future discoveries on #nuclearreceptors ✨️🚀

I am excited to share our work in
J. Mol. Biol. which is our 7th publication on #nuclearreceptors for the 2024 calendar year! Please read on for a summary of all 7 publications from our lab this year, as well as links to the papers.

LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype LRH-1/NR5A2 activation in inflammatory cells of individuals with type 1 diabetes (T1D) reduces pro-inflammatory cell surface markers and cytokine release. LRH-1/NR5A2 promotes a mitohormesis-induce...

Excited to share our latest paper on LRH‐1/NR5A2: targeting mitochondrial dynamics to reprogram macrophages and dendritic cells in T1D into an immune-tolerant phenotype! Thanks to the amazing team&collaborators 🙌 #T1D #Mitochondria #NuclearReceptors #Immunometabolism
doi.org/10.1002/ctm2...

Wow, thanks for the highlight @sbgrid.bsky.social and KeAndreya! #nuclearreceptors

Join Us at ENDO 2025 Join us in San Francisco, CA, July 12-15, 2025, for ENDO 2025 at the Moscone Convention Center. With over 7,000 attendees, nearly 2,500 abstracts and over 200 other sessions, ENDO is the leading globa...

ENDO (Endocrine Society) abstract submission for the 2025 Annual Meeting will open today!! This is my absolute favorite meeting for all things #nuclearreceptors and hormone-dependent cancers 🧪...and catching up with my @nrimpact.bsky.social peeps. Watch this site 👇 for updates

We just got here! 😀We study #transcriptional control of #inflammation, work on #macrophages, 😍 #NuclearReceptors - and 'long walks on the Upper East Side in #NYC Please, bear with us until we find our way around this place. Stop by to say hello!! Hard to find everyone 😃 @wcm-imp.bsky.social

#nuclearreceptors

Insights into the conformational dynamics of Glucocorticoid Receptor AF1 region - a circuit topology analysis of disordered compact regions

www.biorxiv.org/content/10.1...

#nuclearreceptors #IDP #IDR #topology #glucocorticoid

BPS Publications Background and purpose Endocannabinoids are lipid mediators, which elicit complex biological effects that extend beyond the central nervous system. Tissue concentrations of endocannabinoids increase...

A new collaborative paper with Ralf Brandes lab @ Goethe University Frankfurt: endocannabinoids as ligands for NR4A (Nurr1 and Nur77) #nuclearreceptors! doi.org/10.1111/bph....

#nuclearreceptors