📢Client #Publication Spotlight
This study reveals how microglia-derived IL-6 induces astrocyte apoptosis in the hippocampus, driving anxiety- and #depression- like behaviors in a CSDS model.

🔗 www.ebraincase.com/support/cust...

#Neuroscience #DepressionResearch #Microglia #Astrocyte #IL6 #P2X7R

Ruscogenin Ameliorated Sjögren's Syndrome by Inhibiting NLRP3 Inflammasome Activation This article investigated the role and the specific mechanism of Ruscogenin in Sjögren's syndrome (SS). NOD/ShiLtJ mice were treated with Ruscogenin, and acinar cells isolated from submandibular gland...

Has anyone tried Ruscogenin to treat Sjogren's? I see all the indicators it should work: blocks #TLR4, #NLRP3, #MYD88, #NfKB, #P2X7R, #TNF-A and #IL-1B activation, and has been shown in mouse models to ameliorate #Sjogren's

pmc.ncbi.nlm.nih.gov/articles/PMC...