A green sock heel has been darned with golden yellow thread

Sicca, morbid dryness in the body, can make the heels of the feet very hard on favouroite socks, so constant darning is in order 🧵
#Sjögren #SjD #VisibleMending #Kintsugi

#grief #chronicillness #illness #chronicpain #chronicfatigue #Endometriosis #Adenomyosis #ME #CFS #sjogren #Fibromyalgia #YouAreNotAlone ♥️🙏

I REALLY hope 2026 will be a good year🙏❤️
Living with multiple chronic illnesses,and CONSTANT pain and fatigue is soo incredibly hard😢

#newyear #manifest #manifesting #chronicillness #chronicfatigue #ChronicPain #pain #fatigue #Endometriosis #ME #CFS #Fibromyalgia #Sjogren #love #hope #happiness

Novartis ianalumab receives FDA Breakthrough Therapy designation for Sjögren’s disease

www.novartis.com/news/media-r...

👉“Ianalumab has potential to become first targeted treatment for this autoimmune disease with significant unmet need”
#Sjogren #Ianalumab

Literalmente, tengo que esforzarme en mantener los ojos abiertos. Avora mismo no hay punto medio: o miero de dolor o, si me descuido, caigo desplomada.

#zoster #sjogren #tea

My ONLY wish 🙏🏻♥️

#chronicillness #illness #chronicpain #chronicfatigue #invisibleillness #pain #fatigue #AllIWantForChristmas #sleep #nopain #immunesystem #Endometriosis #Adenomyosis #Fibromyalgia #ME #CFS #Sjøgren #Sjogren #youarenotalone

#Sindrome di #Sjogren:

opuscolo illustrativo a supporto dell'incontro in I.C. #Moscati

(12/Dic./2025). #EducazioneCivica & #Scienze - #ScuolaMedia

#Malattie #Rare

www.researchgate.net/publication/...

🎯🎯🎯

#quote #quotes #chronicillness #illness #invisibleillness #chronicpain #pain #chronicfatigue #fatigue #ME #CFS #Fibromyalgia #Endometriosis #Adenomyosis #Sjogren #Sjøgren #Endowarrior #youarenotalone ❤️🙏

#Sindrome di #Sjogren: opuscolo illustrativo a supporto dell'incontro in I.C. #Moscati (12/Dic./2025). #Educazione #Civica & #Scienze - #Scuola #Media.

.. www.researchgate.net/publication/... ..

#chronicillness #invisibleillness #chronicpain #chronicfatigue #pain #fatigue #Fibromyalgia #ME #CFS #sjogren #sjøgren #Endometriosis #Endowarrior #Adenomyosis #youarenotalone ♥️🙏🏻

💯💯💯

#chronicillness #invisibleillness #Fibromyalgia #pain #chronicpain #fatigue #chronicfatigue #Endometriosis #Adenomyosis #ME #CFS #Sjøgren #Sjogren #Exhausting #health #youarenotalone

Efficacy and safety of nipocalimab in patients with moderate-to-severe Sjögren's disease (DAHLIAS): a randomised, phase 2, placebo-controlled, double-blind trial Fc receptor blockade by nipocalimab 15 mg/kg significantly improved clinical disease activity versus placebo and was safe and well tolerated in participants with moderate-to-severe, active Sjögren's d...

www.thelancet.com/journals/lan...

👉”Fc receptor blockade by nipocalimab 15 mg/kg significantly improved clinical disease activity versus placebo and was safe and well tolerated in participants with moderate-to-severe, active Sjögren's disease.”

#Sjogren #PhaseII

GZMK+CD8+ T cells target a specific acinar cell type in Sjögren's disease Sjögren's disease (SjD) is a systemic autoimmune disorder characterized by dysfunction of exocrine glands, particularly the salivary and lacrimal glan…

www.sciencedirect.com/science/arti...

📖 GZMK+CD8+ T cells target a specific acinar cell type in Sjögren's disease

#Sjogren #Tcell

#ACR25 Clinical Year in Review by Dr. Bryant England (1/2): #Sjogren

⭐️ “The name has caught up to the science in Sjogren’s.”
⭐️ Potential role for salivary autoantibodies

#ACRambassador

Facts😢

#chronicillness #chronicfatigue #fatigue #invisibleillness #ME #CFS #Fibromyalgia #Sjogren #Sjøgren #pain #chronicpain #Endometriosis #Adenomyosis #YouAreNotAlone #spoonie

#chronicillness #chronicpain #chronicfatigue #pain #Endometriosis #Adenomyosis #Fibromyalgia #ME #CFS #Sjøgren #Sjogren #youarenotalone ♥️🙏🏻

#chronicillness #invisibleillness #CFS #ME #Fibromyalgia #Endometriosis #Adenomyosis #sjogren #sjøgren #chronicpain #chronicfatigue #pain #fatigue #youarenotalone

♥️♥️♥️🙏🏻🙏🏻🙏🏻

#chronicillness #ChronicPain #chronicfatigue #fatigue #cfs #me #fibromyalgia #Endometriosis #Endowarrior #Adenomyosis #sjogren #sjøgren #pain #illness #invisibleillness #youarenotalone #warrior #fighter

Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjögren’s disease reveals common and distinct immune activation and fibroblast-mediated inflammation - N... Sjögren’s disease (SjD) can be split into different subtypes and these may have different molecular profiles. Here the authors compare anti-SSA and anti-centromere autoantibody positive SjD and show u...

www.nature.com/articles/s41...
📖”Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjögren’s disease reveals common and distinct immune activation and fibroblast-mediated inflammation”
#Sjogren #SSA #centromere

Targeting B-cell activation to tackle both patient-reported and systemic disease outcomes in Sjögren's disease A recent series of studies on Sjögren's disease have shown clustering of patients that share clinical features, such as pain, fatigue, and dryness.1–3 Although these delineations might aid patient str...

www.thelancet.com/journals/lan...

COMMENT
📖“Targeting B-cell activation to tackle both patient-reported and systemic disease outcomes in Sjögren's disease”
#Bcell #Sjogren

#pain #chronicpain #illness #chronicillness #Fibromyalgia #Endometriosis #Adenomyosis #Sjogren #sjøgren

Scleral lenses can change everything for keratoconus patients.
They create a smooth surface for clearer, stable vision—even when glasses and soft contacts fail.
Custom fit with Eaglet ESP

#keratoconus #sclerallenses #cornea #specialtycontacts #sjogren #dryeye #ectasia

“Novartis announces both ianalumab Phase III clinical trials met primary endpoint in patients with Sjögren’s disease “

Great news 👏👏👏
#Rheumsky #Sjogren

🔗 www.novartis.com/news/media-r...

Lactate signalling leads to aggregation of immune-inflammatory hotspots and SLC5A12 blockade promotes their resolution - Nature Metabolism Certo, Pontarini et al. provide insight into the metabolic requirements of ectopic lymphoid structure (ELS) assembly in the context of autoimmunity, and show that blocking lactate uptake by SLC5A12 of...

www.nature.com/articles/s42...
“Here we show that metabolic pathways and specific metabolites, in particular lactate, are master regulators of ELS organization in Sjögren’s disease (SjD), the second-most common autoimmune rheumatic disease.”
#Sjogren #Tcell #Bcell #metabolites

World Sjögren's Day What is World Sjögren's Day?World Sjögren's Day is meant to put a face on the millions of people who live with this disease or suffer from symptoms and have yet to be diagnosed. It gives everyone touched by Sjögren's a vehicle to reach out and educate those close to them - family, friends, co-workers, neighbors, etc. - about the disease. It is the ideal opportunity for you to have your voice heard and to spread awareness about this life-altering disease.

Today is World #Sjögren's Disease Day.
Heading to Dublin for an event in Royal College of Surgeons.
sjogrens.org/get-involved/spread-awar...

Wereld Sjögren Dag 2025: Samen sterk voor betere gezondheid Op woensdag 23 juli 2025 is het Wereld Sjögren Dag. Op deze dag vragen mensen over de hele wereld aandacht voor het syndroom van Sjögren.

Wereld Sjögren Dag 2025: 𝗦𝗮𝗺𝗲𝗻 𝘀𝘁𝗲𝗿𝗸 𝘃𝗼𝗼𝗿 𝗲𝗲𝗻 𝗯𝗲𝘁𝗲𝗿𝗲 𝗴𝗲𝘇𝗼𝗻𝗱𝗵𝗲𝗶𝗱
Op deze dag vragen mensen over de hele wereld aandacht voor het syndroom van Sjögren. Dit is een chronische ziekte, toch is het nog weinig bekend.

reumazorgnederland.nl/wereld-sjogr...

#sjogren #wereldsjogrendag

📣Happening tomorrow✨

July 23rd is #WorldSjogrensDay 😊

To raise awareness, an exciting webinar hosted by #APLAR will be held tomorrow📺👇

Register🔗 us06web.zoom.us/webinar/regist…

#Sjogren #AYR #APLAR #JCR

T follicular helper 1 cells in blood potentially mirror salivary gland-infiltrating T cells in Sjögren’s disease - Scientific Reports Scientific Reports - T follicular helper 1 cells in blood potentially mirror salivary gland-infiltrating T cells in Sjögren’s disease

www.nature.com/articles/s41...

Happy (or more like relieved 🫠❣️) to finally share that my work is out!
It definitely took a while, but I’ve learned so much along the way.

Even more grateful that I get to keep going on this research journey for a few more years🙏!!
Let’s keep going 😀👣
#Sjogren #Tfh

Mirad donde he pasado la mañana, en urgencias.Te puedes cuidar mucho,pero el sistema inmunológico es así 🤦La primera otitis del verano. Gotas, antibiótico y esperar que todo vaya bien😔 De momento debo descansar #Sjogren #artritisreumatoide #SanidadPublica

Just starting #childhood #MCTD #Sjogren #PReS 💻⬇️