Local #Immunometabolic #Intervention with #Alanyl-glutamine Resolves #Peritoneal Dialysis-Induced #Immune Cell Dysfunction
#VisualAbstract by Kajaree
www.kireports.org/article/S2468-0249(26)02...
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#Peritoneal
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What is peritoneal dialysis? #peritonealdialysis #dialysis #peritoneal #kidneyhealth ... Continue to: www.youtube.com/watch?v=A3R2...
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BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway
This study shows that #BoneMarrowMesenchymalStemCells-derived #Exosomes exert protective effects on #PeritonealDialysis-related #PeritonealFibrosis, mediated by #miR27a3p/#TP53 pathway & regulation of #Peritoneal miRNA #Homeostasis. #medsky
Read: link.springer.com/article/10.1...
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The struggle was real.
I turned our bedroom into a cleanroom, my son's room became partially a storage facility for dialysis materials, transfer fluids, cabling, sterile resources.
One day I will tell you ALL about it. But not today. I will need way more coffee for that.
#peritoneal #dialysis
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3 days a week, she spent four hours sitting in a room at 50° F while they filtered her blood through a #hemodialysis unit. She did that for five years.
Before that, we tried doing home-based #peritoneal dialysis. Surgical alterations were made so she could be safe at home. That lasted four years.
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This study shows that #Peritoneal #AdiposeDerivedStemCells orchestrate #disease progression and #Metastasis in #OvarianCancer through #ExtracellularVesicle-mediated, long-range modulation of #EGFR and #NFκB signaling pathways. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
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#Exit-Site Care in Pediatric #Peritoneal #Dialysis Patients: From Personal Preference to Clinical Evidence
https://doi.org/10.1016/j.ekir.2025.09.036
Original Article: https://doi.org/10.1016/j.ekir.2025.08.021
#KIRCommentary
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Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy #HIPEC in #peritoneal sarcomatosis: Therapeutic advancement or clinical controversy? An institutional review
www.surgjournal.com/article/S003...
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Clinical manifestations of #peritoneal #TB include ascites (93%), abdominal pain (73%), fever (58%) Typically, sx for week or months before dx.
>90% with tb peritonitis have ascites at time of presentation, with SAAG<1.1 g/dL (in the absence of cirrhosis)
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#Peritoneal #TB occurs most commonly following reactivation of latent tuberculous foci in the peritoneum established via hematogenous spread from a primary lung focus
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peritoneal biopsies showed caseating granulomas #peritoneal #tb #Mycobacterium #tuberculosis Ref t.co/rD772Gs7f1
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Great presentation by @carloberg.bsky.social at the 1st International Meeting on Cellular and Molecular Peritoneal Dialysis Research in 🇩🇪 Kiel on how to reduce glucose absorption in #peritoneal #dialysis patients
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A firework of mechanistic data by @rebeccaherzog.bsky.social on how negative effects of glucose in #peritoneal dialysis could be attenuated.
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Flow cytometry characterization of the peritoneal niche
#macrophages also showed (i) decreased relative abundance and (ii) increased numbers in the #peritoneal niche with aging. With all these changes, it was likely that #macrophages would see functional remodeling, which led us to focus on the interplay of sex and aging on these cells. 3/13
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Single cell RNA-seq profling of the mouse peritoneal cavity with aging
This work started with a simple question 8 years ago: how do #sex and #age impact #immune aging in mice 🐁? We decided to use the #peritoneal cavity as a test case, starting with @10xgenomics.bsky.social scRNA-seq 🧬of niche cells, showing that #macrophages were the most responsive cell type! 2/13
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#preprint alert! Excited to share a #biobank of patient-derived #appendix cancer models, including matched primary-metastasis pairs, with novel insights into mechanisms and drug targeting of #peritoneal #carcinomatosis. Led by our 1st PhD student Ahmed Mahmoud
www.biorxiv.org/content/10.1...
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Excellent new article from specialist nurse Samantha Westbrook about #peritoneal #Mesothelioma with important implications for practice onlinelibrary.wiley.com/doi/10.1155/.... Funded by @mesouk.bsky.social at the Mesothelioma UK Research Centre in @fohsheffield.bsky.social.
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ASCO released an update for advanced-stage #ovarian, #fallopiantube or #peritoneal #cancer that recommends evaluation by a gynecologic oncologist before starting treatment & offering somatic & germline testing for #BRCA & other ovarian cancer genes.
ascopubs.org/doi/10.1200/...
@tpalmd.bsky.social
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Woo! No more #peritoneal #dialysis fluid boxes in the basement! I finally managed to empty the remaining... 30-40 boxes and drain the bags!
He's been on #hemo dialysis for 2 years now? And ofc we had just gotten a month's supply when he had to switch to hemo (got an infection).
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Hi @bsky.app #peritoneal #dialysis aficionados : what is your first diagnosis ? 😉
Nephrology zebra released today in the Journal of Nephrology
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The PDTAP Study on #Haemoglobin Cut-Offs in #Peritoneal #Dialysis
The PDTAP study examines Hb thresholds and their impact on outcomes in incident peritoneal PD patients.
What Hb levels should clinicians target to minimize risks?
#Nephrology #PeritonealDialysis
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study design - identified datasets, and retained datasets after QC filtering
Together with undergraduate #OliviaWhite, we asked whether we could observe #sexdimorphic gene expression in mouse #macrophages from different niches. We curated publicly available RNA-seq datasets, as well as generated some new in-house RNA-seq datasets on #peritoneal macrophages and #BMDMs. 2/7
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Method of prevention of post-operative peritoneal adhesions #peritoneal #adhesions #some4pedsurg #sminaev #some4surgery #SurgSky #MedSky pubmed.ncbi.nlm.nih.gov/36910438/
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#Peritoneal -#Dialysis: CAPD vs. APD – A Choice That Matters
A perspective paper explores the decision-making process between CAPD and APD emphasizing that this choice should be guided by individual preferences and lifestyle, rather than automated assumptions.
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I am so looking forward to attending #Peritoneal Summit 15–17 JAN 2025 in beautiful Pontresina, coörganized by @zindellab.bsky.social & @ingekherrmann.bsky.social! It should be a great meeting on the burgeoning field of body cavity #immunity!
Come join us! The abstract deadline is 30 NOV!
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