#PolyamineMetabolism #SkeletalMuscle #Aging
Depletion of S-adenosylmethionine (SAM, methyl donor) ➡️loss of #Heterochromatin➡️#MuscleStemCell #Aging
⏫SAM or⏬#SpermidineSynthase by MCHA▶️
⏫#SkeletalMuscle regeneration
#NatMetab 2024
www.nature.com/articles/s42...
pmc.ncbi.nlm.nih.gov/articles/PMC...
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