Silencing YAP/TAZ lowers SOX2 in #Mammospheres, reducing sphere formation and viability, modulating #RedoxHomeostasis, regulating mitochondria, and via DRP1 impairing #OXPHOS to eliminate #chemoresistant #brCSCs.

#STTT #OpenAccess: doi.org/10.1038/s413...

Online now - the Feature Review "Regulating #Nrf2 activity: #ubiquitin ligases and signaling molecules in #RedoxHomeostasis" from Albena Dinkova-Kostova and colleagues.

#RedoxSwitch #Keap1 #SQSTM1

Read it here 👉 authors.elsevier.com/sd/article/S...