Novel Mechanism Regulates Essential Enzyme Production in Kidneys  - News Center Scientists have discovered previously unknown cellular mechanisms that regulate the production of renin, an essential enzyme in the kidney, findings that could improve the understanding of how the kidney regulates its function and how chronic kidney disease develops, according to a recent study published in Cell.

Scientists have discovered cellular mechanisms that regulate #renin production, an essential enzyme in the #kidney, findings that could improve our understanding of #kidney function and chronic #KidneyDisease, per @cp-cell.bsky.social. spr.ly/63321hdsov

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#GAMA #RENIN
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📰New & Featured | #PIEZO2 is a regulator of juxtaglomerular granular cell calcium dynamics and #renin
🔸PIEZOs loss ablates mechanically activated currents in vitro
🔸PIEZO2 suppresses renin in hypervolemia/normovolemia and is a brake on the hormonal response to hypovolemia

Post-treatment renin status and cardiovascular, renal, and mortality outcomes in medically treated primary aldosteronism: a systematic review and meta-analysis The association between unsuppressed renin following medical therapy for primary aldosteronism and reduced risk of cardiovascular events and all-cause mortality suggests that renin normalisation might...

The association between unsuppressed #renin following medical therapy for primary #aldosteronism and reduced risk of #cardiovascular events and all-cause mortality suggests that renin normalisation might serve as a therapeutic target thelancet.com/journals/lan...
#CVD

#MedSky #EndoSky #CardioSky

Primary aldosteronism and plasma renin targets Over the past two decades there have been tremendous advancements in the understanding of both the prevalence and the clinical significance of primary aldosteronism. Where previously only the most ext...

Linked Comment by Kevin S Fay & Debbie L Cohen:
Primary #aldosteronism and plasma #renin targets www.thelancet.com/journals/lan...

#MedSky #EndoSky #CardioSky

The association between unsuppressed #renin following medical therapy for primary #aldosteronism and reduced risk of cardiovascular events and all-cause mortality suggests that renin normalisation might serve as a therapeutic target www.thelancet.com/journals/lan...
#primary #aldosteronism

#EndoSky

Our findings reinforce the clinical importance of post-treatment #renin as a biomarker to assess the efficacy of medical treatment for #primary #aldosteronism, particularly for #cardiovascular protection thelancet.com/journals/lan...
#secondary #hypertension #CVD

#MedSky #EndoSky #CardioSky

Primary aldosteronism and plasma renin targets Over the past two decades there have been tremendous advancements in the understanding of both the prevalence and the clinical significance of primary aldosteronism. Where previously only the most ext...

Linked Comment by Kevin S Fay & Debbie L Cohen:
Primary #aldosteronism and plasma #renin targets www.thelancet.com/journals/lan...

#MedSky #EndoSky #CardioSky

Post-treatment renin status and cardiovascular, renal, and mortality outcomes in medically treated primary aldosteronism: a systematic review and meta-analysis The association between unsuppressed renin following medical therapy for primary aldosteronism and reduced risk of cardiovascular events and all-cause mortality suggests that renin normalisation might...

The association between unsuppressed #renin following medical therapy for primary #aldosteronism and reduced risk of #cardiovascular events and all-cause #mortality suggests that renin normalisation might serve as a therapeutic target www.thelancet.com/journals/lan...

#MedSky #EndpoSky #CardioSky

Definition of renin Explore the definition of the word "renin" with example sentences, synonyms, and related terms to improve your English skills.

renin
- A proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure

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#definition #renin #meaning #english #ielts

●膽固醇及荷爾蒙

研究顯示，血液中
總膽固醇的濃度
在冬天會來到高峰，
而膽固醇會減損
#內皮細胞 的功能，
進而造成血管硬化。

有研究指出，
一些和血管活性相關而引起血壓高的荷爾蒙，

例如： #醛固酮
（ #Aldosterone ），

正腎上腺素

（ #Norepinephrine ），
及 #腎素（ #Renin ），

在冬天會比夏天分別上升59%、19%，以及17%。

5種人需特別注意血壓變化

The renin–angiotensin–aldosterone-system in sepsis and its clinical modulation with exogenous angiotensin II - Critical Care Dysregulation of the renin–angiotensin–aldosterone-system (RAAS) in sepsis is a complex and early phenomenon with a likely significant contribution to organ failure and patient outcomes. A better unde...

'A better understanding of the pathophysiology and intricacies of the RAAS in septic vasodilatory shock has led to using exogenous angiotensin II as a new drug to treat sepsis. The use of angiotensin II may improve outcomes' #critcaresky #emimcc #RAAS #renin
ccforum.biomedcentral.com/articles/10....