HARKing: Hypothesizing After the Results are Known - The Broken Science Initiative By Norbert L. Kerr Summary This paper by psychologist Norbert Kerr discusses the emerging practice in science of asserting a hypothesis after an experiment has [...]

🧪 A literary description of #HARKing #ReplicationCrisis #ResearchWaste
Hypothesising after the results are known

Nice blog here with the original paper by psychologist Norbert Kerr brokenscience.org/harking-hypo...

NEW PREPRINT: “A critical review of clinical prediction models in oncology: is this SEERious research?”

--> doi.org/10.31222/osf...

#ClinicalPredictionModels #ResearchIntegrity #ResearchWaste #metascience #metaresearch

Dichotomization is only one of the issues leading to the vicious circle of #ResearchWaste. Many reasons, one I'm finding deeply troubling, being the suboptimal (oh, I'm polite), suboptimal (quantity & quality) education in biostats & research methods in med schools. #MedEd has serious catch up to do

INSPECT-SR is a tool to address risks posed by untrustworthy randomized controlled trials:
www.cochrane.org/about-us/new...

The focus is on use in #SysReviews, but I think it may offer opportunities for training in #RCT methods.

I'll find out - just registered 👇

#ResearchWaste #ResearchIntegrity

5th Evidence-Based Research Conference

Check out final program for the Evidence-Based Research Conference.

Join us (virtual is option, though not as much fun!)!

#evidencebasedresearch #researchintegrity #researchwaste

www.hvl.no/en/research/...

Mike Clarke: How can we avoid research waste during the covid-19 pandemic and plan for the future? - The BMJ Around the world and across disciplines, researchers have turned their attention to covid-19, but we need to ensure this effort is a help rather than a hindrance, says Mike Clarke [...]More...

#CochraneDaily #PubMed has reached 11,000 records for systematic reviews relevant to #COVID-19 13 months after reaching 10,000. How many of these are needed? How much research waste do they represent, 5 years on from this opinion piece: blogs.bmj.com/bmj/2020/04/...
#ResearchWaste
#EvidenceSynthesis

just read a #stats paper which advised that if your #neuroscience data are skewed you should discard the top & bottom 10% & compute 'trimmed means' which are 'more robust' (transformation was dismissed as an alternative)

i'm sorry if you read that advice & deleted 20% of your data 🫣

#ResearchWaste

Isn’t this a role for #preprints? Widely disseminated, findable, citable reports on what doesn’t work - my sister is a computational organic chemist - I have always wondered why they don’t report reactions that don’t work - and save everyone else time and money #ResearchWaste

Some tags
#Metascience #NewPI #Drosophila #Celegans #Zebrafish #Danio #Genetics #ReproSci #ResearchIntegrity #ScientificPublishing #SciPub #AcademicSky #Immunity #InnateImmunity #NewPI #PhDchat #Science #Replicability #Reproducibility #Science #OpenScience #ResearchWaste #OpenAccess

Is there a reproducibility crisis in science? - Matt Anticole View full lesson: http://ed.ted.com/lessons/is-there-a-reproducibility-crisis-in-science-matt-anticolePublished scientific studies can motivate research, ins...

Why does reproducibility matter? Matt Anticole’s video explained the reproducibility crisis and remaining challenges eight years ago (buff.ly/2DkbSBE). Many of them are still unsolved. Join us at researchagora.com to help strengthen science for everyone.

#Reproducibility #OpenScience #ResearchWaste

I enjoyed reading this. It's important to question if research is needed. And, if so, by whom and in what direction? Many scholars and practitioners are encouraged to DO research rather than USE research. #ResearchWaste is a problem. As is lack of synthesising and implementing evidence.

New NIOO publication: Supporting study registration to reduce research waste, by @antica_c and others.
#preregistration #registeredreports #ecology #researchwaste #researchprocess #openscience
https://doi.org/10.1038/s41559-024-02433-5

The most important question before supporting any #OpenScience initiative is how exactly it helps build a usable and reliable scientific knowledge base.

Few do.

#ResearchWaste

Exploring trial publication and research waste in COVID-19 randomised trials of hydroxychloroquine, ... Background The global research response to the COVID-19 pandemic was impressive, but also led to an infodemic and considerable research waste. Registered, but unpublished trials added to this noise. W...

Looking at COVID-related #RCTs registered btw [01 Nov 19 - 31 Dec 21] available via WHO #ICTRP, authors find that less than a third made their results public and registry entries were frequently not updated:
bmcmedresmethodol.biomedcentral.com/articles/10....

#ResearchWaste #SysReview

Looking for something to continue the #ISOQOL buzz?

How about reading "Reducing research wastage by starting off on the right foot" from QLR's special issue on #ResearchWaste?


Editorial introducing the articles:


#HRQL
@ISOQOL

Preparing for our workshop at #ISOQOL23?

Have a look at this paper about starting off on the right foot by framing a good research question


From our special section on #ResearchWaste in #HRQL research


@ISOQOL @claudia_ruthers

Is my study useless? Why researchers need methodological ... Making researchers account for their methods before data ...

Excellent summary of great ideas to prevent #ResearchWaste due to poor #StudyMethods. Strong plea to only embark on research that can answer its questions. https://go.nature.com/3Gfr7RP
@WCRIFoundation @lakens @OSFramework @openscience @RetractionWatch

Statistical code for clinical research paper...

Vickers
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705117/

#MedMastodon
#OpenScience
#ResearchWaste
#doi:10.7326/M17-2863
https://mastodon.social/@JessButler/109420776361520929 (3/3)

1/10 The QLR-@ISOQOL conference issue in Oct will contain the special section (w @claudia_ruthers):

"Reducing #ResearchWaste in (health-related) quality of life research"


#PrePrint

#HRQL #HealthEconomics
@SpringerPBH

From @ISOQOL's QualityTALK 👇

The paper shows ANZCTR-registered trials increasingly include patient-reported outcomes and asks, how many of them do/will report their results?

Our forthcoming editorial on #ResearchWaste:

🔥📢 #PrePrint of our (w @claudia_ruthers) editorial for a special section that focuses on a topic that has so far received limited attention in our research & practice community:
#ResearchWaste


Articles:
👉

@ISOQOL @SpringerPBH

In an update of earlier work, @Nancy2Mayo & team suggest better framing of #HRQoL #QoL research questions for our special section on reducing #ResearchWaste in (Health-Related) Quality of Life Research:


#PhDChat

A contribution to our section on "Reducing #ResearchWaste in (Health-Related) Quality of Life Research" describes the development of a process for improving the translation of research into practice and aligning it with knowledge gaps:


#HRQoL
@ISOQOL

For our section on #ResearchWaste in (Health-Related) Quality of Life Research this paper discusses opportunities in & barriers to #HRQOL research using data linkages, based on a case example & legislation in Australia:


#DataSharing #HealthPolicy
@ISOQOL

A case study in our forthcoming special section on #ResearchWaste in (Health-Related) Quality of Life Research illustrates how poor reporting of #HRQOL instruments impacts on time and completeness of #SysReviews:


#HealthEconomics
@ISOQOL

Most of the papers for the special section "Reducing #ResearchWaste in (Health-Related) Quality of Life Research" have been accepted now.

1st paper published deals w
"Power(ful) myths: misconceptions regarding sample size in #QoL research"


#HRQoL @ISOQOL

Great graphics in this paper (https://bit.ly/2QdbYKq on the importance of #OpenScience practices and removing perverse incentives that hamper #ResearchIntegrity and lead to #ResearchWaste.
@WCRIFoundation @NRIN_Integrity @EmbassySci @sops4ri