Individual lipid alterations at the origin of neuronal Ceramide Synthase defects Authors summary The brain is the most lipid-enriched organ of our body. At the same time, it is highly susceptible to disturbances in lipid metabolism. In this context, ceramide metabolism deserves sp...

Individual lipid alterations at the origin of neuronal Ceramide Synthase defects #CerS. #PLoSGenet @unibonn.bsky.social #ThieleLab; #BauerLab; #SobaLab; #brain; #lipid #metabolism; shorturl.at/O6LBn

Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner Maternal obesity is a growing health concern that predisposes offspring to metabolic dysfunction, immune system alterations, and neurodegenerative dis…

Developmental #programming by #maternal #obesity alters offspring #lifespan and immune responses in a diet- and sex-specific manner. #Cells&Development @masslab.bsky.social #HasenauerLab #ThieleLab #BauerLab @unibonn.bsky.social #Hemocytes; #Macrophages; #Metabolism; #Plasmatocytes. rb.gy/pe6d15

Phosphatidylcholine synthesis and remodeling in brain endothelial cells Mammalian cells synthesize hundreds of different variants of their prominent membrane lipid phosphatidylcholine (PC), all differing in the side chain …

Phosphatidylcholine synthesis and remodeling in #brain #endothelial #cells #JLipidRes #ThieleLab @unibonn.bsky.social #alkyne #tracer; #lipidomics; #lysophosphatdiylcholine; #phospholipase shorturl.at/NGLyE