MCS Ultrastructural Analyses Using Electron Microscopy
@contactctc.bsky.social
@journals.sagepub.com
journals.sagepub.com/doi/10.1177/...
#endosome #mitochondria #membranecontactsites #biology #openaccess
Zang, DeSantis et al @umich.edu reveal CCSer2 as a Ndel1 binding protein that regulates #dynein activity at the cell periphery. Loss of CCSer2 disrupts #centrosome positioning & early #endosome trafficking, causing migration defects in developing #zebrafish & cell culture rupress.org/jcb/article/...
Zang, DeSantis et al @umich.edu reveal CCSer2 as a Ndel1 binding protein that regulates #dynein activity at the cell periphery. Loss of CCSer2 disrupts #centrosome positioning & early #endosome trafficking, causing migration defects in developing #zebrafish & cell culture rupress.org/jcb/article/...
Read our latest blog on the Commander complex, an assembly coordinating endosomal protein sorting, and its role in diseases.
📖 5 min read: ow.ly/k4Yz50VvHQN
Try a FREE Nano-Trap® sample: ow.ly/Wyos50VvHQK
#CellBiology #Endosome #CommanderComplex
Lipid juggling: Any1 scrambles membranes for #endosome biogenesis.
Sinead Iduna Schwabl, Konstantin Adrian Siegmann, and David Teis (@teislab.bsky.social) discuss new work by Gao et al. from the Ungermann Lab (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...
Any1 is a phospholipid scramblase involved in #endosome biogenesis, say Jieqiong Gao, Christian Ungermann and colleagues (Osnabrück University): rupress.org/jcb/article/...
#Membrane #lipid #Organelles #Biochemistry
Coordination between #ESCRT function and Rab conversion during #endosome maturation
Anne Spang and colleagues @biozentrum.unibas.ch show that early ESCRT complexes shepherd cargoes towards sites of intraluminal vesicle formation in a key step of endosome maturation
www.embopress.org/doi/full/10....
Interested how events are coordinated during #endosome maturation? Check out our latest paper! Congrats Daniel, Samit and Jachen!
www.embopress.org/doi/full/10....
