This review explores the #mTORpathway structure and its molecular regulation, highlighting the therapeutic potential of targeting mTOR in #ClinicalTrials and its critical interplay with mitochondrial function. @univparissaclay.bsky.social
#STTT #OpenAccess: doi.org/10.1038/s413...
This review outlines recent progress in treating #DiabeticNephropathy via drugs and molecules targeting the #mTORpathway, offering insights for improved prevention and therapy. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
Our findings suggest that everolimus is a promising precision therapy for NPRL2- and NPRL3-related epilepsy, with the potential to reduce seizure frequency, thereby improving patient quality of life.
doi.org/10.1111/epi....
#epilepsy #Epilepsia #ILAE #everolimus #GATOR1complex #mTORpathway
Key point: Analysis of cortical samples from HMG patients reveals abnormal development of Pvalb interneurons, which acquire cytomegalic features.
doi.org/10.1111/epi....
#epilepsy #ILAE #corticaldevelopmentaldisorders #interneurons #mTORpathway #neocortex
mTOR pathway: A key player in diabetic nephropathy progression and therapeutic targets
This bibliometric analysis discusses mTOR signaling-associated pathological mechanisms in various renal cell types within a #diabetic environment & highlights the therapeutic implications of targeting the #mTORpathway in #DiabeticNephropathy. #medsky
#OpenAccess: www.sciencedirect.co...
Scientists decode ovarian aging with groundbreaking molecular atlas 🌟🧬📊 www.news-medical.net/news/2024112... #Ovaries #Aging #Fertility #mTORPathway #GeneExpression #Biology #Epigenomics #HealthInnovation #CellularAging #ReproductiveHealth #OvarianScience
