Scales, feathers, or both? Evidence points to mostly scaly adult T. rex, with possible fuzzy juveniles—and color hints preserved in melanosomes. What do you picture? #DinosaurColor #Dinosaurs #Feathers #Melanosomes #TRex
#WeekendRead! #SmartTumor #EveryCellIsAnImmuneCell! Levy & (many) friends show @cp-cell.bsky.social that melanoma tumors release large extracellular vesicles #melanosomes decorated with MHC-I & high affinity tumor associated antigens which subvert cytotoxic T cells! www.cell.com/cell/fulltex...
📰New & Featured | A study in #Cell discovered that secretion of #melanosomes can be blocked to enhance tumor #immunity
🔹Presence of melanosomes➡️poor prognosis + reduced T cell cytotoxicity + less responsive to immunotherapy
🔹Melanosome carry #TAAs and #neoantigens
#Melanoma
Image credit: Valentina Rossi
But on a microstructural level, the story is different. Using #SEM imaging, we identified #melanosomes (melanin-bearing cells) and analysed their shape @ucc.ie. They turned out to be most similar to feathers among skin tissue types in amniotes.
🎨 Scientists just reconstructed the color of a 15-million-year-old fish for the first time using fossilized pigment cells!
Ferruaspis brocksi had a striped body, pale belly & dark back—thanks to well-preserved #melanosomes in iron-rich #goethite rock. #Miocene
www.smithsonianmag.com/smart-news/p...
#adaptation
#melanosomes
#biochemistry
Sunday just so story
How mammals of the Mesozoic with uniform dark brown and nocturnal habits to better avoid being noticed by giant dinosaurs, acquired many coloured striped and spotted furs after the giants became extinct.