If you're interested in the factors that enable the regular structure of CNS #myelin sheaths by #oligodendrocytes, check this out. Featuring a #CDC42 - effector proteins - #septin axis. Congrats to 1st author Sophie, and a big thank you to all who contributed
onlinelibrary.wiley.com/doi/10.1002/...
Very excited to share the latest work from our lab in @insight.jci.org, highlighting a role for the #septin #cytoskeleton in protecting against "leaky gut", by recruiting non-muscle myosin II and stabilizing the tight junction.
Credit to @dominikrobak.bsky.social for the stunning cover image!
Bni5 regulates and coordinates #septin architecture and #myosin-II functions at the #CellDivision site, say Hiroki Okada, Erfei Bi and colleagues @upenn.edu: rupress.org/jcb/article/...
#Cytoskeleton #CellCycle #Biochemistry #Genetics #Cytokinesis
#Lipid packing and local geometry influence #septin curvature sensing, say Brandy Curtis, Amy Gladfelter @gladfelterlab.bsky.social and colleagues @duke-university.bsky.social: rupress.org/jcb/article/...
#Biochemistry #Cytoskeleton
In @jcb.org, Okada, Bi et al. @upenn.edu show that Bni5 interacts with #septin filaments, septin-associated kinase, and #myosin-II to regulate septin hourglass architecture and remodeling, retrograde #actin flow, and #cytokinesis. rupress.org/jcb/article/...
#CellDivision #Cytoskeleton #Genetics
Okada, Bi et al. @upenn.edu show that Bni5 interacts with #septin filaments, septin-associated kinase, and #myosin-II to regulate septin hourglass architecture and remodeling, retrograde #actin flow, and #cytokinesis rupress.org/jcb/article/...
#Biochemistry #CellDivision #Cytoskeleton #Genetics
Localization of the #septin #cytoskeleton is controlled by regulatory factors, membrane curvature, & charge. In this study, @gladfelterlab.bsky.social finds changes to #lipid composition that modulate lipid packing defects to impact septin assemblies in vitro & in cells. rupress.org/jcb/article/...
Localization of the #septin #cytoskeleton is controlled by regulatory factors, membrane curvature, & charge. In @jcb.org, @gladfelterlab.bsky.social finds changes to #lipid composition that modulate lipid packing defects to impact septin assemblies in vitro & in cells. rupress.org/jcb/article/...
Attention #Septin Fans! Serge Mostowy's lab @sergemostowylab.bsky.social published a wonderful #openacces short report in #CYTOSKELETON.Comparative Analysis of Septin Modifiers, Forchlorfenuron and UR214-9, on Mitochondrial Fragmentation and Lytic Cell Death. onlinelibrary.wiley.com/doi/full/10....
New study @jcb.org from Shannon, Trimble and colleagues @sickkidsto.bsky.social: Exploring the #septin #cytoskeleton at an organelle interface informs on mitochondrial fission and concerted actions between members of the cytoskeleton. rupress.org/jcb/article/...
#Mitochondria
New study from Shannon, Trimble and colleagues @sickkidsto.bsky.social: Exploring the #septin #cytoskeleton at an organelle interface informs on mitochondrial fission and concerted actions between members of the cytoskeleton. rupress.org/jcb/article/...
#Mitochondria
Sorry for interrupting the regularly scheduled doom and gloom...
REGISTER NOW for
FASEB #SEPTIN MEETING in
Niagara Falls, NY (June 15-19)
First US septin meeting in 15 years!
Lots new and exciting science.
Get outta of your gloom &
find your septin boom!
events.faseb.org/event/septin...
#Septin starter pack is here!
Join it, if you must, and help it grow by reposting it.
go.bsky.app/RohumAf
