🔥 #Lactate used to be thought of as a metabolic “waste product”
But new research shows it can:
📉 reduces #heat-driven metabolic activity
⚡ boosts #mitochondrial function
🛡️ lowers heat-induced #cell death
👉 A role in cellular #protection
https://ow.ly/LiOy50YHJB8
Posts by Biochemistry and Cell Biology
Robert Kiss recognized as Outstanding Reviewer 2025 by Biochemistry and Cell Biology, affiliated with McGill University, Canada.
BCB proudly recognizes Robert Kiss from McGill University as a 2025 Outstanding Reviewer for quality, timeliness, and volume of reviews. Congrats, Robert!
Learn more about our Outstanding Reviewers ⭐▶️ https://ow.ly/aw7u50YLiV7
#OutstandingReviewer
🌿 #Enzymes that build #health-related molecules found in balloon #flower
⚙️ convert basic #sugars into building blocks
🔬 work as predicted when tested in #bacteria
👉 Helping us understand how therapeutic compounds are made
https://ow.ly/qFMF50YHJH1
🦴 Healing #bone isn’t just about #stem cells—it’s about what’s blocking them!
Under #inflammation, bone-forming cells slow down
New research shows miR-20b-5p can:
⬇️ Reduce cellular stress
⬆️ Restore bone-building activity
https://ow.ly/3W4R50YHJws
🐝 Protecting #bees means thinking bigger
New #research highlights that bee health is shaped by:
🧬 3genetics + 🦠 #microbiomes + 🤝 social behavior + 🌍 #environment
A more holistic view could be key to supporting pollinators under environmental #stress
https://ow.ly/WUUi50YHJvU
🧬 Pseudogene-derived variant (UbKEKS) looks like #ubiquitin—but behaves differently
🔄 binds different set of targets
🧠 shifts protein interactions due to structural changes
🚫 can’t signal proteasomal degradation
👉 Tiny sequence change = major rewiring
https://ow.ly/6UPR50YHJFN
SOX2 enhancers are like switches in the #brain 🧬—but each study calls them something different! New #review maps them all out & proposes a universal naming system. #Science just got a little less confusing #Neurobiology #Genomics
https://ow.ly/Oms450YqsHv
Red background with bold white text announcing a new agreement between Canadian Science Publishing and the University of Oslo.
NEW! Our Read and Publish agreement with #UIO has been extended through 2028, giving affiliated authors, including those at Oslo University Hospital, read access and publishing open access options at no cost.
Learn more ▶️ https://ow.ly/hrQ050YtwBo
#uio Universitetet i Oslo #AcademicPublishing
🧬 New work revisits an old favorite: hydrochloric acid-based #histone extraction! Simple, reliable, and compatible with SDS, 2D gels, and mass spec—making histone prep easier for downstream #analyses. #Epigenetics #HistoneResearch #MolecularBiology
https://ow.ly/vAp550Yh28O
From low-coverage reads to near-complete #genomes! 🔬 Researchers show ONT reads corrected with NGS rival more expensive hybrid sequencing for #genome #assembly 🧬#GenomeResearch #ONT #NGS #GenomicsInnovation
https://ow.ly/4Xt250Yh1RZ
Close-up of a vibrant blue and orange poison dart frog on an orange flower, with text announcing a Peer Review Coordinator job opening at Canadian Science Publishing.
Canadian Science Publishing is #hiring a Peer Review Coordinator to manage peer review, support authors, reviewers, and editors, ensuring quality and timeliness. Learn more and apply: https://ow.ly/RpUF50YqbyY
#PeerReview #SciencePublishing #AcademicJobs
Close-up of a green leaf background with text announcing a Sales Operations & Customer Support Specialist job opening at Canadian Science Publishing.
Canadian Science Publishing is #hiring a Sales Operations & Customer Support Specialist to support subscribers and authors with journals, products, and services.
Learn more and apply before Mar. 26: https://ow.ly/gqiu50YpU6i
#SalesOperations #CustomerSupport #JobOpening
Red background with bold white text announcing a new agreement between Canadian Science Publishing and ETH Zürich logos.
#NewAgreement! ETH Zurich corresponding authors can continue to read and publish open access at no cost under the renewed agreement with Canadian Science Publishing, now extended through 2028. Learn more ▶️
https://ow.ly/87kL50YtASO
#AcademicPublishing
🍔➡️🧬 High-fat, high-sugar diets can wreak havoc on the #liver—but NEDD4L overexpression flips the switch, reducing #ferroptosis and preventing MAFLD-related liver #damage. Targeting this pathway could inspire new therapies! #MetabolicHealth
https://ow.ly/Q6VS50Yh223
#Pseudogenes aren’t always silent 🧬 RPS27AP5, once considered non-functional, produces a #ubiquitin variant (UbP5) and #ribosomal #protein variant (S27aP5) that alters #mRNA association, adding evidence for ribosome diversity 👏
https://ow.ly/hsNn50Yh11e
🧠 SOX2 is a key #transcription factor for brain development & neural #stem cells—but its enhancers have been all over the map! New review untangles years of data and offers a unified roadmap for understanding SOX2 regulation across species #Neuroscience
https://ow.ly/shyk50YqsEP
💊 Combining old and new: Actinomycin D + resveratrol shows enhanced #cancer cell killing in vitro via p53 activation—but in vivo, the combo doesn’t outperform the single agents. #CancerResearch #p53 #DrugSynergy
https://ow.ly/4zxx50Yh2co
ERα drives most #breastcancers — but context matters 🧫 Cofactor partnerships and genomic binding differences may explain why ovarian & uterine #cancers respond differently to therapy 👩🏾🔬 #InternationalWomensDay
https://ow.ly/sF5M50Yh1jm
Close-up of dandelion seeds with overlay text announcing a job opening for a Digital Publishing Specialist at Canadian Science Publishing.
Canadian Science Publishing seeks a Digital Publishing Specialist to manage metadata, support our journal platform, and improve workflows. Apply before Mar. 26 ▶️ https://ow.ly/lkKa50Yq9ux
#DigitalPublishing #PublishingJobs #MetadataManagement
A #ubiquitin variant hiding in a #pseudogene? UbKEKS (from UBBP4) looks like canonical ubiquitin — but NMR reveals structural & dynamic shifts that prevent K48-linked proteasomal degradation and reshape its substrate profile 🧫
https://ow.ly/ugo950Yh0MI
Proper #brain development depends on SRCAP-driven H2A.Z deposition 🧠 Disrupting SRCAP alters #chromatin dynamics and neurodevelopmental #gene expression — advancing our understanding of developmental #disorders 🧬 #DevelopmentalDiseasesDay
https://ow.ly/oo4s50Yh0Gw
Rare #disease research reveals fundamental #biology 🧬 Disruption of KAT3A (CREBBP) & KAT3B (EP300) underlies Rubinstein-Taybi syndrome and informs mechanisms in #Alzheimer's disease and #Huntington's disease 🧠 #RareDiseaseDay
https://ow.ly/B6kU50Yh0hI
Cervical cancer cells can become resistant to cisplatin (cDDP), a key chemotherapy drug 😟. New research shows that the tumor suppressor TRIM3 helps fight this resistance by targeting a stress-related protein, GRP78. #CancerResearch #CervicalCancer
https://ow.ly/q0y350XW85B
#Diarrhea from E. coli is a major health problem in humans and animals 🦠💊 New research shows that combining bovine lactoferrin (bLf) with an antimicrobial peptide (N6) can help protect the gut and reduce inflammation #GutHealth #InfectiousDisease
https://ow.ly/nIZ950XW7ZH
Why do #anti-estrogen therapies work so well in #breast #cancer but not in ovarian or uterine cancers, even when they all express ERα? 🤔 New research suggests it may depend on which cofactors ERα teams up with! #CancerResearch #BreastCancer
https://ow.ly/bY1950XW7Ll
Canadian Science Publishing seeks Interim Editorial Director for Biological and Environmental Journals, with a green plant background.
#Hiring!
We are looking for an Interim Editorial Director to oversee our biological and environmental science journals. If you have a background in academic publishing and a drive to support research, this could be the perfect opportunity to make an impact.
Apply now ▶️ https://ow.ly/tCa550Y9sUN
Cover of Biochemistry and Cell Biology journal featuring a detailed illustration of a green cell with filamentous structures on a blue background.
Our most read article of 2025 explores opportunities, challenges, and ethics of AI in academia. Read it now ▶️ https://ow.ly/HYmb50XVzfj
👥: Joshua Molligan, Edel Pérez-López 🇨🇦
#BestofCSP Université Laval
🔖 During #mitosis, most #gene expression shuts down—but mitotic bookmarking keeps key regulatory proteins & lncRNAs on chromatin, guiding the next generation of cells.
Aberrant bookmarking can disrupt #tumor suppressors & proto-oncogenes 🧬
#Epigenetics #CancerResearch
Person in outdoor gear taking a selfie in a forest with trees and sunlight filtering through promoting new Canadian Science Publishing Blog post
What can forestry teach us about impact, patience, and perspective? Read our new conversation piece with Dr. Nelson Thiffault, Co-Editor-in-Chief of the Canadian Journal of Forest Research, on the #CSPBlog 💡▶️ https://ow.ly/Ob8y50XMykP
#ForestScience #ResearchImpact #ScholarlyPublishing
It’s the perfect time of year to grow your #network!
This networking guide is packed with #practicaltips to help you navigate networking in the new year.💡Read now on the #CSPblog ▶️ https://ow.ly/YMeU50XFZE3