Advertisement · 728 × 90

Posts by Gaia Trincucci

Our view of new (and old but re-formulated) determinants of myeloid biology in tumors is out in @jem.org! Amazing work from #marianogales #mariolamunarriz, #teresaaceña, & a fantastic editing process (thanks @gaiajexpmed.bsky.social). Hope you like it! #cancerimmunitylab @cniostopcancer.bsky.social

1 month ago 13 5 0 0
Post image

Sticky memories of an activated #macrophage. Luca Frosio and Renato Ostuni @ostunilab.bsky.social @unisr.bsky.social discuss new findings by Gorin et al. (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/...

#InnateImmunity #inflammation

1 month ago 3 2 0 0

Welcome to @jem.org!

3 months ago 6 3 0 0

Welcome to @jem.org!

3 months ago 6 3 0 0
Preview
Neutrophils preserve energy storage in sympathetically activated adipocytes - Nature Neutrophil-derived IL-1β has a role in preserving lipid stores during metabolic stress.

Today’s #JEMjc @jem.org highlights the work of Alan Saltiel & colleagues @nature.com reporting the role of neutrophil-derived IL-1β in preserving lipid stores during metabolic stress.

www.nature.com/articles/s41...

4 months ago 11 4 0 0
Site-specific regulation of Th2 differentiation within lymph node microenvironments | Journal of Experimental Medicine | Rockefeller University Press The authors show that early Th2 cell differentiation is driven via prolonged T–DC macro-clustering in lymph nodes and occurs in a skin site-specific manner

Today's #JEMSpotlight @jem.org highlights the work of Michael Gerner & colleagues investigating early Th2 differentiation in lymph nodes after cutaneous allergen administration with quantitative imaging 📸

rupress.org/jem/article/...

4 months ago 3 1 0 0
Preview
SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS 1. Sera from individuals acutely ill with lobar pneumonia possess the capacity to precipitate in high titre a non-protein somatic fraction derived from pne

#JEMLegacy @jem.org goes back to 1930 with the first description by William Tillett and Thomas Francis Jr. of C-reactive protein (CRP) in the sera of patients during the acute phase of pneumococcal pneumonia.

@RockUPress @RockefellerUniv

rupress.org/jem/article/...

4 months ago 7 4 0 0
Post image

This #JEMLegacy tweet highlights two papers from 1965 by Drs. Phil Gold and Samuel O. Freedman @mcgill.ca on the discovery of the Carcinoembryonic Antigen (CEA), the basis for the widely used CEA blood test.
rupress.org/jem/article/...
rupress.org/jem/article/...

#cancer #biomarker #CEA

6 months ago 4 3 1 0
Post image

A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

6 months ago 154 72 2 12
Advertisement

Wonderful symposium & location!
Happy to chat! 🙋‍♀️

6 months ago 5 0 0 0
Post image Post image Post image Post image

What a fantastic day to start the Immunobiology of #PRRs Symposium in beautiful Lausanne! Much looking forward to being part of an amazing line up of speakers, & to presenting a brand new story on a 100-year old protein whose function remains poorly understood! 😉

6 months ago 8 1 1 0

Excited to be part of this Women in STEM Viepoint 🌟 Huge thanks to @jem.org for the invite - what an inspiring lineup!

7 months ago 10 3 1 0

Another wonderful lineup of #WomeninSTEM for this @jem.org Viewpoint series!

7 months ago 8 1 0 0

Thank you @jem.org for the invite to participate in this Viewpoint alongside such inspiring scientists 🤩🤩

7 months ago 11 4 2 0

📣 Journal Editors at EMDS2025:Scotland Edition

@gaiajexpmed.bsky.social, Deputy Editor @jem.org, will be in Edinburgh at #EMDS2025 next week. Reach out to her to discuss your work. Also, check out the Special Collection @jem.org on #macrophage & #dendriticcells

@efis-immunology.bsky.social

7 months ago 5 4 0 0
Post image

Attending #EMDS2025 (@emds2025.bsky.social) in Edinburgh and want to learn about publishing with JEM? 🔬 ✏️ 📄 Meet our Deputy Editor Gaia Trincucci (@gaiajexpmed.bsky.social) who will be there and chat about your research!
📨 Connect with Gaia via email: rupress.org/jem/pages/ed...

7 months ago 4 2 0 0

New insights from @quintanalabhms.bsky.social @jem.org

7 months ago 4 2 0 0

Happy to get to contribute to this perspective in JEM!

8 months ago 31 7 0 0

I had fun thinking about this and reading the advice from other women that I really respect! Thank you @jem.org for the opportunity.

Find your people and do science with your friends

8 months ago 6 3 0 0
Advertisement
Post image

Scripps Research Assistant Professor Alejandra Mendoza (@thepenkpanther.bsky.social) was recently featured in @jem.org’s ‘Women in STEM’ series alongside other scientists to share her journey and advice on fostering an environment where great science can thrive.

Read more: ow.ly/rFeI50WEbC7

8 months ago 9 3 0 0
Post image

New review from Venkatesh and Fong @fredhutch.bsky.social describes how tumor-reactive CD4 T cells are functionally impaired in #cancer, including similarities/differences with CD8 T cells, and how immunotherapies can help overcome this. rupress.org/jem/article/...

#CancerFocus #Immunotherapy

8 months ago 4 3 0 0
Post image

Early and opposing #neutrophil and CD4 T cell responses shape pulmonary #tuberculosis pathology, say Benjamin Gern @bengern.bsky.social, Michael Gerner, Kevin Urdahl et al. rupress.org/jem/article/...

#TB

8 months ago 4 2 0 0

Attending #Cytokines2025? Are you a grad student or an early career postdoc? Don't miss the opportunity to apply to the @jem.org Early Career Travel Award!

More here👉 hubs.la/Q03yQFLq0

8 months ago 6 4 0 0

Quite proud of this labor of love!
Humans are exposed to fungi, inhaling hundred/thousands of spores daily. Immunocompromised patients (chemo, transplant) are at risk for certain fungal infections. But, what about people who don't have these risk factors? This enigma has peppered the literature...

10 months ago 18 3 2 0

Looking forward attending EACR2025! Happy to chat! 🙋‍♀️

10 months ago 3 1 0 0
IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints
IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints Original paper: https://rupress.org/jem/article/222/7/e20231882/277976/IRF7-controls-spontaneous-autoimmune-germinalVideo summary by Adam Fike (Pennsylvania ...

🎥 New video summary of the study "IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints" from Adam Fike, Ziaur Rahman @spt-gc.bsky.social‬ and colleagues (rupress.org/jem/article/...) 👇

youtu.be/h_ADv6ncups

10 months ago 3 2 0 0
Post image

New review from Reglero Real, Rolas, and Nourshargh explores how #aging alters the microvasculature and surrounding stromal cells, disrupting immune cell trafficking and promoting chronic #inflammation. rupress.org/jem/article/...

10 months ago 5 2 0 0
Post image

Attending @keystonesymposia.bsky.social‬''s on #Neuroimmunology and #Neurodegeneration? Meet our Sr. Scientific Editor Lucie Van Emmenis! @lucie-jexpmed.bsky.social will be participating in Meet the Editors session 🗓️ Tues. June 10, 3:30pm – 4:30pm!

See our collection 👉 rupress.org/jem/collecti...

10 months ago 7 4 1 1
Advertisement
DNGR-1 regulates proliferation and migration of bone marrow dendritic cell progenitors | Journal of Experimental Medicine | Rockefeller University Press Cardoso et al. show that DNGR-1–deficient pre-cDCs display cell-intrinsic alterations in their ability to colonize peripheral organs. Their findings highli

#WeekendRead #LocationLocationLocation#MoreThanCrossPresentation! @reisesousalab.bsky.social, Cardoso &co show @jexmed.bsky.social that DNGR1 other than enabling crosspresentation by cDC1s limits seeding of pre-DCs in peripheral tissues, but determines their proper localization in the periphery!

10 months ago 8 2 0 0
“What’s in a name?” Clarifying the identity of RORγt+ antigen-presenting cells | Journal of Experimental Medicine | Rockefeller University Press Sun et al. highlight eTACs as a key component in the group of RORγt+ antigen-presenting cells acting in the induction of RORγt+ pTregs specific to food ant

Great piece in @jem.org by Ken Murphy's group on RORγt APCs in peripheral Treg induction #Immunology

10 months ago 8 3 0 0