How to enjoy Easter chocolate without wrecking your sleep If you love a late-night chocolate egg, you may struggle to sleep. A sleep expert explains why.

"Eating #chocolate in the evening may cause #AcidReflux because ingredients such as caffeine & theobromine relax the muscles that keep #stomach acid in place. Chocolate also has a high #fat content, which can slow digestion.": buff.ly/etOI3QF

via @theconversation.com
#sugar #gastric #ChronicPain

Join us April 3 at 1-2 PM ET for the Addiction Toxicology Case Conference on “#Gastric Bypass and the Effect on Addiction and SUD." This FREE webinar is available to everyone! Register: https://bit.ly/4deVQRk

Non‐Pulmonary Mechanisms of Action of Ambroxol in In Vivo Experimental Models: a Systematic Review Background Repositioning offers a cost-effective approach to discovering new therapeutic applications for existing medications. Ambroxol, primarily used as a mucolytic for respiratory diseases, has ...

Now available in OA:
Non-Pulmonary Mechanisms of Action of Ambroxol in In Vivo Experimental Models: a Systematic Review
#clinical #pharmacology #ambroxol #analgesic #antioxidant #antinociceptive #inflammation #SFPT #gastric #skin @wileyhealth.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...

Long-Term Proton Pump Inhibitor Use Not Linked to Gastric Adenocarcinoma There was no association observed between long-term proton pump inhibitor use and gastric adenocarcinoma.

Long-term #PPI use seems not to be associated with an increased risk for #gastric #adenocarcinoma.

Read More: https://bit.ly/4c7NxpC

Key Points • We employed Atmo Capsules to measure the frequency and amplitude of stomach contractions using a method called accelerometry which detects changes in capsule orientation and acceleration. • Stomach contractions occurring at a frequency of 3 cycles per minute were found which were lower in amplitude in patients with delayed gastric emptying compared to healthy controls and individuals with normal gastric emptying. • This technical assessment provides support for the Atmo Capsule accelerometer to characterize normal and abnormal stomach contractile profiles in patients with suspected motility disorders.

🆕🔥Accelerometric assessment of #Gastric Contractility using #Atmo Wireless Motility Capsule‼️
🎯Atmo Capsule enables precise quantification of gastric contraction profiles, permitting differentiation of normal from pathological motor patterns👏
👉 onlinelibrary.wiley.com/doi/10.1111/...
#NGM #ANMS #ESNM

🎓️ EDITOR'S CHOICE 🎓️

Chou et al. show that cough depends on the proton content of #gastric contents and is mediated by acid-sensing ion channels on vagal afferents. This work has relevance for the prevention of aspiration #pneumonia 🫁

📜 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...

Positive #controls: bacteria spike-in, and importantly, GI tumors with well established bacteria: e.g. #Helicobacter #pylori in #gastric cancer, #Fusobacterium in #colorectal cancer. 5/

✔️ Evidence-aligned, clinician-reviewed
✔️ Ideal for exam preparation & refreshers
✔️ See how you rank on the global leaderboard

#Gastric #GastricCancer #Oncology #OncoIQ #MedicalEducation #GIOnc

Stop Wasting Your Nutrients: How to Increase Protein Absorption In today's episode we're exploring why eating protein isn't the same as absorbing it, distinguishing simple consumption from actual cellular utilization. We dive into the science of bioavailability to ensure you aren't wasting your nutrients through poor digestion or common dietary mistakes. You will learn how to optimize stomach acid with apple cider vinegar, leverage proteolytic enzymes from tropical fruits, and neutralize anti-nutrients in plant proteins. We also debunk the 30g protein myth and explain why leucine and Vitamin B6 are critical for muscle synthesis. Stop flushing your gains away and start maximizing your results today. References:https://foodnourish.net/how-to-increase-protein-absorption/ Support Foodnourish Deep Dives Become a supporter for just 2€ per month. This removes any advertisements and help us continue bringing more interesting topics and confronting mainstream narrative on health. Link to support: https://www.spreaker.com/podcast/foodnourish-deep-dives--6602003/support

📣 New Podcast! "Stop Wasting Your Nutrients: How to Increase Protein Absorption" on @Spreaker #absorption #anabolism #bioavailability #bromelain #digestion #enzymes #fitness #gastric #health #leucine #metabolism #muscle #nutrition #papain #peptides #probiotics #protein #supplements #synthesis

Michael Camilleri writes this #TopicalReview examining #incretin impact on #gastric function in obesity through physiology, and pharmacological, surgical and endoscopic treatments🥼 🔃

🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Can AI-Assisted Endoscopy Improve Optical Diagnosis of Gastric Neoplasia? Computer-aided diagnosis does not improve the optical diagnosis of gastric neoplasia in nonexpert endoscopists.

#AI may not improve the optical diagnosis of #gastric malignancies.

Read More: https://bit.ly/3JZyin5

Tislelizumab + Chemotherapy in Gastric Cancer: Long-Term RATIONALE-305 Randomized Trial Follow-up - Advances in Therapy Introduction Tislelizumab + chemotherapy has shown promising results as first-line treatment for advanced gastric/gastroesophageal junction adenocarcinoma (GC/GEJC). We present long-term safety and ef...

Tislelizumab + Chemotherapy in #Gastric #Cancer: Long-Term RATIONALE-305 Randomized Trial Follow-up link.springer.com/article/10.1... #hvhebron #onco [Text complet]

Top: Experimental set up. Single pulses of TMS were applied to the hand area of the right primary motor cortex with an inter-pulse interval randomized between 6 and 10 s. Simultaneously, the neuronavigated coil position (yellow), electrocardiogram (red), respiratory signal (blue), electrogastrogram (green), and electromyography from the left hand (gray) were recorded. The figure shows traces of a 20-s time segment from one participant of the cardiac (raw), respiratory (filtered), gastric (filtered), and EMG (raw) signals. The experimental measure was the Motor Evoked Potential amplitude measured on a hand muscle (first dorsal interosseous), analyzed against the phase of the cardiac, respiratory, and gastric rhythms. Note that the three rhythms have very different periods (~1 s for the heart, ~ 5 s for respiration, and ~20 s for the gastric rhythm). Bottom: Artwork illustrating how rhythms of the internal organs interact with the moment-to-moment fluctuations observed in corticospinal motor excitability. Image depicts an outline of a brain with representations of the three rhythmic organs influencing the motor system: the heart, lungs, and stomach. Image credit: Tahnée Engelen.

How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT

Top: Experimental set up. Single pulses of TMS were applied to the hand area of the right primary motor cortex with an inter-pulse interval randomized between 6 and 10 s. Simultaneously, the neuronavigated coil position (yellow), electrocardiogram (red), respiratory signal (blue), electrogastrogram (green), and electromyography from the left hand (gray) were recorded. The figure shows traces of a 20-s time segment from one participant of the cardiac (raw), respiratory (filtered), gastric (filtered), and EMG (raw) signals. The experimental measure was the Motor Evoked Potential amplitude measured on a hand muscle (first dorsal interosseous), analyzed against the phase of the cardiac, respiratory, and gastric rhythms. Note that the three rhythms have very different periods (~1 s for the heart, ~ 5 s for respiration, and ~20 s for the gastric rhythm). Bottom: Artwork illustrating how rhythms of the internal organs interact with the moment-to-moment fluctuations observed in corticospinal motor excitability. Image depicts an outline of a brain with representations of the three rhythmic organs influencing the motor system: the heart, lungs, and stomach. Image credit: Tahnée Engelen.

How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT

Top: Experimental set up. Single pulses of TMS were applied to the hand area of the right primary motor cortex with an inter-pulse interval randomized between 6 and 10 s. Simultaneously, the neuronavigated coil position (yellow), electrocardiogram (red), respiratory signal (blue), electrogastrogram (green), and electromyography from the left hand (gray) were recorded. The figure shows traces of a 20-s time segment from one participant of the cardiac (raw), respiratory (filtered), gastric (filtered), and EMG (raw) signals. The experimental measure was the Motor Evoked Potential amplitude measured on a hand muscle (first dorsal interosseous), analyzed against the phase of the cardiac, respiratory, and gastric rhythms. Note that the three rhythms have very different periods (~1 s for the heart, ~ 5 s for respiration, and ~20 s for the gastric rhythm). Bottom: Artwork illustrating how rhythms of the internal organs interact with the moment-to-moment fluctuations observed in corticospinal motor excitability. Image depicts an outline of a brain with representations of the three rhythmic organs influencing the motor system: the heart, lungs, and stomach. Image credit: Tahnée Engelen.

How do internal bodily rhythms influence #brain activity & motor function? @tahnee-engelen.bsky.social &co show that #cardiac, #respiratory & #gastric rhythms independently modulate motor excitability, revealing distinct #interoceptive profiles across individuals @plosbiology.org 🧪 plos.io/4nMtpLT

Researchers identified four potential drug targets for #Gastric #SignetRingCell #Carcinoma, and #MolecularDocking identified #Neratinib as a promising therapeutic option, providing new avenues for cancer therapy. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Perioperative Durvalumab in #Gastric #Cancer www.nejm.org/doi/10.1056/... #hvhebron #onco

#ESMO25: Phase III FORTITUDE-101 #ClinicalTrial reports improved short-term survival with first-in-class FGFR2b inhibitor bemarituzumab added to chemotherapy to treat FGFR2b-overexpressing #Gastric or #GEJCancer.
More in the #ESMODailyReporter ➡️ https://ow.ly/C2MU50Xf08l

Molecular roadmap links stomach infection to cancer risk Gastric cancer remains one of the world’s leading causes of cancer deaths, yet the molecular steps driving its onset remain elusive.

Molecular roadmap links #stomach #infection to #cancer risk ...

| #Gastric | #Helicobacter | #bacteria | #carcinogenesis | Via eurekalert .org

Examination of effects of Roux-en-Y #gastric #bypass surgery (an effective treatment option for #obesity) on #indole metabolite profile in the gut reports that
these metabolites do not support #metabolic benefits of RYGB, but may contribute to post-surgery #gut #inflammation
doi.org/10.14814/phy...

Inside Facts⁠
⁠
badgut.org/information-...
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#gastroparesis #GIcondition #awareness #gastric #gastroparesiswarrior #gastroparesissucks #gastroparesisfighter #gastroparesishope

Inside Facts
badgut.org/information-...

#gastroparesis #GIcondition #awareness #diabetes #gastric #gastroparesiswarrior #gastroparesissucks #gastroparesisfighter #gastroparesishope

Living with #oesophageal or #gastric cancer can feel confusing and isolating. #MyDiCECompanion is a free 📲 app designed to make things a little easier.

It helps you track your symptoms & your progress.

🔗https://mydicecompanion.eu/

@esge-news.bsky.social @esperity.bsky.social @eortc.org

NCCN released updated Genetic/Familial High-Risk Assessment: #Colorectal, #Endometrial, #Gastric #Cancer guidelines on June 13th, including updates to clinical diagnostic criteria for #PeutzJeghersSyndrome among many other important updates. Read more at www.nccn.org/professional...

Treating a common bacteria could reduce gastric cancer cases worldwide As many as 15.6 million people born between 2008 and 2017 globally are expected to develop gastric cancer sometime in their life, suggests a study published in Nature Medicine.

Treating a common #bacteria could reduce #gastric #cancer cases worldwide ...

| #Helicobacter | #microbe | #stomach | #infection | Via @sciencex.bsky.social

Watch an exciting presentation from the @NCCN 2025 Annual Conference to learn about genes related to #prostate, #endometrial, & #gastric #cancers as well as the expanded recommendations in the #NCCN Guidelines for Genetic/Familial High-Risk Assessment ⤵
education.nccn.org/node/97031

Dana-Farber Report Shows Alarming Rise in Many Gastrointestinal Cancers in Young People Dana-Farber Cancer Institute experts report findings from a literature review that rates of early onset gastrointestinal cancers are rising rapidly, with the youngest groups experiencing the highest rise in rates. These alarming rises apply not just to colorectal cancer, but also to pancreatic cancer, esophageal and stomach cancers, as well as rarer gastrointestinal cancers of the appendix, biliary cancer, and neuroendocrine tumors.

A new report from @danafarber.bsky.social highlights rising rates of GI cancers in young adults - not just #colorectal, but also #pancreatic, #esophageal, #gastric, #biliary & more.

Read more: bit.ly/40D0kd8

Controversies in upper GI oncology: the definition and management of oligometastatic gastroesophageal tumours In this Controversies in upper GI oncology podcast, Angelica Petrillo, gastrointestinal oncologist of Ospedale del Mare, Naples, Italy, presents a discussion between Professor Hanneke van Laarhoven,

Another fantastic @myesmo.bsky.social GI oncology podcast about #oligometastatic #gastric cancer is finally out!

Please take a moment to 🎧 and share it with your team:

soundcloud.com/esmo-podcast...