#MarieCurieActions #MSCA #DoctoralNetworks #HorizonEurope #H2020 #ResearchImpactEU #IntegratedStressResponse #Autoimmunediseases #Dendriticcells

This research letter provides a proof of concept that the pharmacological or genetic inhibition of mTOR sensitizes T-cell acute lymphoblastic leukemia cells to #Venetoclax via the sustained activation of #IntegratedStressResponse. #medsky

#OpenAccess: doi.org/10.1038/s413...

Have you ever wondered what are the mediators and effects of mitohormesis in organisms? In our review, we explore the unexpected path of mitochondrial stress to systemic benefits. 🔥 #mitochondria #mitohormesis #integratedstressresponse @ucberkeleyofficial.bsky.social

Online today: Convergent activation of the #IntegratedStressResponse and ER–mitochondria uncoupling in VAPB-associated #AmyotrophicLateralSclerosis

By C. Landry, H. Miranda & colleagues at Case Western Reserve University

➡️ doi.org/10.1038/s443...

#IntegratedStressResponse #UnfoldedProteinResponse #DendriticCells #Interferon #ISR #UPR #DCs #IFN @ciml.bsky.social @cnrs.fr @cnrsbiologie.bsky.social @univ-amu.fr

#HappyResearcher #Immunology #IntegratedStressResponse #DendriticCells #SLE #SAVI #ISR #MarieCurieActions #MSCA #DoctoralNetworks #HorizonEurope (7/7)

Honored to be working on the Characterization of rare gene variants affecting the Integrated Stress Response in dendritic cells and interferonopathies at @ciml.bsky.social in P. Pierre’s lab.
And grateful to be part of the @immerge.bsky.social program!

#ISR #IntegratedStressResponse #SAVI #SLE

#Neurodegeneration
#Alzheimer’s #Microglia
#DarkMicroglia
#IntegratedStressResponse #ISR #SRIInhibition
#Research #Neuroscience

🙋 Are you studying the Unfolded Protein Response (UPR) and/or the Integrated Stress Response (ISR)?

👇🏻 Let’s all gather here!

Thank you @profmarciniak.bsky.social!

#UPR #ISR #UnfoldedProteinResponse #IntegratedStressResponse