…Dinah Lange of the #TheobaldLab at #UniversityHospitalCologne & @unicologne.bsky.social for her talk on intracellular signaling cascades and cell death mechanisms of #DendriticCells induced by #Mycobacterium tuberculosis infection. Congrats 🎉@dgfi-org.bsky.social @dgfi-yi.bsky.social #DGHM

Novel role of Hippo effector YAP1 as a rheostat controlling inflammation in dendritic cells YAP1 regulates inflammatory responses in human dendritic cells under hypoxic conditions by controlling oxidative stress, signaling pathway activation, and

Sara Monaci and colleagues identify a "Novel role of Hippo effector #YAP1 as a rheostat controlling #Inflammation in #DendriticCells"

Delve into recent JEM studies in the fields of #hematopoiesis and #myeloid lineages, incl. the role of neutrophils in myocardial & vascular injury, the characterization of intrarenal myeloid cells, a deeper understanding of the origin & function of #DendriticCells & more: rupress.org/jem/collecti...

New research sheds light on why eczema so often begins in childhood – BioNews Central Researchers discovered that certain immune cells in early-life skin are more reactive than in adults, which may explain why eczema often begins in childhood. ...

Researchers discovered that certain #ImmuneCells in early-life #skin are more reactive than in adults, which may explain why #eczema often begins in #childhood. 
#AtopicDermatitis #DendriticCells #AllergicInflammation

Thymic myeloid cells are heterogenous and include a novel population of transitional #DendriticCells. From Matouš Vobořil, Kristin Hogquist and colleagues: rupress.org/jem/article/...

📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...

#KSMyeloid26 #KSHemato26

#Radiotherapy induces YTHDF2 in #DendriticCells impairing cross-presentation and T cell function, from Dapeng Chen, Chuan He, Hua Laura Liang, Ralph Weichselbaum et al: rupress.org/jem/article/...

📘 In #Hematopoiesis & #Myeloid Cells collection: rupress.org/jem/collecti...

#KSMyeloid26 #KSHemato26

Are you obsessed with #DendriticCells? Curious? Running into them in your experiments?

Then ✳️ #DC2026 is your meeting!

Registration & abstracts are OPEN.
Top-tier speakers and more to come.

⭐️ Come for the science. Stay for the community. @maxkrummel.bsky.social @zunigalab.bsky.social

Dendritic cell maturation in cancer - Nature Reviews Cancer Dendritic cells (DCs) shape the adaptive immune response to peripheral tissue antigens and, as such, are crucial for mounting an effective antitumour immune response in cancer. This Review outlines the molecular basis of DC maturation, highlights the mechanisms through which cancer impairs DC maturation and considers the potential for DC-focused cancer immunotherapeutics.

🥳 Our 6th most downloaded #REVIEW in 2025:

Dendritic cell maturation in cancer

#dendriticcells #TME @NatResCancer
#NRCtop10of2025

Another pre-print now out from the Everts' Group! For those interested in #immunometabolism #DendriticCells #Type2Immunity. Post-translational O-GlcNAcylation is a process required selectively for Th2 priming by DC.
www.biorxiv.org/content/10.6...

Finally, my PhD project is published! 🎉

I am thankful to all the collaborators who made this possible!

www.nature.com/articles/s41...

@natcomms.nature.com
#dendriticcells #immunesynapse #centrosome

Classic Lasker: Ralph Steinman - Lasker Foundation What was life like for Lasker Laureates while they were doing their Award-winning work? Listen in as Award Winners share their personal stories. You will hear about starting off in research during a World War, learn how Laureates navigated family and career, and find out how

#LaskerLaureate Ralph Steinman was born #OTD. He won a #LaskerAward for the discovery of #DendriticCells . 🧪
📖: https://ow.ly/uoMN50XWoRC
🎧: https://ow.ly/P1aY50XWoRB

#immunology The Rockefeller University

#Claudin 1-mediated positioning of DC1 to mTECs is essential for maintenance of central #tolerance. New study from Jiří Březina, Dominik Filipp and colleagues @imgprague.bsky.social @czechacademy.bsky.social: rupress.org/jem/article/...

#Autoimmunity #DendriticCells

In @jem.org, Březina, Filipp et al. @czechacademy.bsky.social show that #Claudin 1 enables thymic type 1 #DendriticCells to localize in close proximity to medullary thymic epithelial cells, supporting the maturation & tolerogenic function of type 1 dendritic cells rupress.org/jem/article/...

Březina et al. @czechacademy.bsky.social show that #Claudin 1 enables thymic type 1 #DendriticCells to localize in close proximity to medullary thymic epithelial cells, supporting the maturation & tolerogenic function of type 1 dendritic cells rupress.org/jem/article/...

#Tolerance #Autoimmunity

Children w/ #bronchiolitis exhibit a unique immunophenotype. Hickey, @bogunoviclab.bsky.social et al identify a significant difference in plasmacytoid #DendriticCells & #eosinophils in hospitalized patients, plus differences in cytokines involved in airway #inflammation rupress.org/jhi/article/...

In @jhumimmunity.org, Hickey, @bogunoviclab.bsky.social et al identify a significant difference in plasmacytoid #DendriticCells & #eosinophils in hospitalized patients, plus differences in cytokines involved in airway #inflammation rupress.org/jhi/article/...

Trms rapidly establish antiviral states in barrier tissues during reinfection, but the mechanisms remain unclear. Hernández-García, Iborra et al reveal that #Trm recruit plasmacytoid #DendriticCells, which promote antiviral immunity through type I IFNs rupress.org/jem/article/...
#MucosalImmunology

New study by Tam et al. (rupress.org/jem/article/...) reveals that GPR34, a lysophosphatidylserine receptor, promotes apoptotic cell uptake and cross-presentation by type 1 #DendriticCells (cDC1s). Insights from Bosteels, Stainier, and @reisesousalab.bsky.social: rupress.org/jem/article/...

Chen, Weichselbaum et al. @ludwigcancer.bsky.social discover that YTHDF2 in #DendriticCells negatively regulates antitumor immunity of #radiotherapy (RT), providing a clinically actionable strategy to overcome RT resistance and #metastasis. rupress.org/jem/article/...

#TumorImmunology #SolidTumors

AC/DC: Highway to Cell. Victor Bosteels (@victor-bosteels.bsky.social), William Stainier, and Caetano Reis e Sousa (@reisesousalab.bsky.social) @crick.ac.uk discuss work by Tam et al. (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/...

#InnateImmunity #DendriticCells

Scientists decipher #PDAC immune evolution at single-cell resolution, revealing direct tumor-induced #dendriticcells #apoptosis via the ANXA1-FPR1/3 axis and illuminating #ImmuneEvasion mechanisms and therapeutic targets. #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

Insights @jem.org: Bosteels, Stainier, and @reisesousalab.bsky.social highlight work by Tam et al. (rupress.org/jem/article/...) revealing that GPR34, a lysophosphatidylserine receptor, promotes apoptotic cell uptake and cross-presentation by type 1 #DendriticCells. rupress.org/jem/article/...

Insights: Bosteels, Stainier, and @reisesousalab.bsky.social highlight work by Tam et al. (rupress.org/jem/article/...) revealing that GPR34, a lysophosphatidylserine receptor, promotes apoptotic cell uptake and cross-presentation by type 1 #DendriticCells. rupress.org/jem/article/...

#Radiotherapy induces YTHDF2 in #DendriticCells impairing cross-presentation and T cell function, say Dapeng Chen, Chuan He, Hua Laura Liang, Ralph Weichselbaum @ludwigcancer.bsky.social and colleagues: rupress.org/jem/article/...

#TumorImmunology #SolidTumors

Chen, Weichselbaum et al. @ludwigcancer.bsky.social discover that YTHDF2 in #DendriticCells negatively regulates antitumor immunity of #radiotherapy. The SPI1–YTHDF2–Notch signaling–MHC-I axis orchestrates the antigen cross-presentation function of dendritic cells. rupress.org/jem/article/...

In @jem.org, Chen, Weichselbaum et al. discover that YTHDF2 in #DendriticCells negatively regulates antitumor immunity of #radiotherapy. The SPI1–YTHDF2–Notch signaling–MHC-I axis orchestrates the antigen cross-presentation function of dendritic cells. rupress.org/jem/article/...

We are happy to welcome Jonas Loosen! ✨
As part of his Master’s in Biomedical Sciences, Jonas is conducting his project work in the lab of @luberod.bsky.social and in close collaboration with the IMMH.
His project focuses on how short-chain fatty acids influence #DendriticCells #Metabolism.

Thymic myeloid cells are heterogenous and include a novel population of transitional #DendriticCells, say Matouš Vobořil, Kristin A. Hogquist @cfi-umn.bsky.social and colleagues: rupress.org/jem/article/...

#Hematopoiesis #Tolerance #LymphocyteBiology

#MarieCurieActions #MSCA #DoctoralNetworks #HorizonEurope #H2020 #ResearchImpactEU #IntegratedStressResponse #Autoimmunediseases #Dendriticcells

ICYMI: Our new collection highlights recent advances in our understanding of #macrophages and #dendriticcells, and their roles in #infection, #allergy, #cancer, #neuroinflammation, and #neurodegeneration. Explore new research 👉 rupress.org/jem/collecti...