My continued biomedical education

Cholesterol crystals in the pathogenesis of #Atherosclerosis\

Lysosomal dysfunction/rupture
NLRP3 #Inflammasome
CC Emboli

Imaged on section with polarized light

You can find CC even in placenta #Preeclampsia 😬

#NatRevCardiol 2024
www.nature.com/articles/s41...

My continued biomedical education

Long non-coding RNAs in #CardiacHypertrophy & #HeartFailure: functions, mechanisms & clinical prospects

Da-Zhi Wang lab #NatRevCardiol 2024
www.nature.com/articles/s41...

My continued biomedical education

Atherosclerotic plaque stabilization & regression
A review of clinical evidence

Imaging modalities
Druggable targets
Trials->Residual risk reduction after max LDL-C reduction

Ashish Sarraju & Steven Nissen #NatRevCardiol 2024
www.nature.com/articles/s41...

My continued biomedical education

Specialized Pro-resolving Mediators in #VascularInflammation & #AtheroscleroticCardiovascularDisease

Resolvin
Protectin
Maresin

#EndothelialCell + #Neutrophil in SPM synthesis

⏫Mφ #efferocytosis #MERTK #FAO

#NatRevCardiol 2024
www.nature.com/articles/s41...