We have been granted a key #patent for our CRISPR-BMC genome-editing technology. This patent opens significant potential for the further commercial application of the patented nucleases. Press release: t1p.de/pbgn7 #enzyme #protein #smallmolecules #CRISPR
💊 Biologics and small molecules for psoriasis: current and future progress
Potestio et al.
@drugsincontext.bsky.social #dermatology #psoriasis #biologics #smallmolecules #pharmacology #MedSky #PharmSky
@medsky.social @me.pharmsky.app
www.drugsincontext.com/biologics-an...
Come and speak to us about all things #peptides #smallmolecules and #medicinalchemistry at the EFMC-ASMC x International Symposium on advances in synthetic and medicinal chemistry.
#medchem #ASMC #EFMCASMC2025 #EFMC
💓 Researchers in the @josesilvalab.bsky.social used #SmallMolecules to convert mouse ESCs into embryo founder cells, which generated a complete embryo model!
Article: bit.ly/4orpbLb
Episode with discussion: bit.ly/4oTURt2
A new postdoc position in our group will open early next year — looking for candidates with a proven track record & relevant experience.
If #CRISPRscreens, #syntheticlethality, #smallmolecules & #celldeath excite you, let’s talk! DMs welcome.
pls share 🙏
Gate enters into a collab & license agreement w #Lilly to discover/develop molecular gate medicines > #smallmolecules that can eliminate disease-causing proteins modulating the secretory translocon
Undisclosed upfront & equity investment, total deal up to $856m
www.businesswire.com/news/home/20...
A picture of Baltimore with a call to meet us at ASMS 2025 at Baltimore Convention Center in Maryland on 01.-05. June 2025 at Booth 208. The Bright Giant logo and the hashtag SIRIUSEvents.
🚨 Join us at #ASMS2025! 🚨
Catch us at Booth 208 to see SIRIUS in action — our all-in-one software for #AI -driven #StructureElucidation of #SmallMolecules.
Let’s connect, talk science, and push the boundaries of small molecule analysis.
More updates soon 👀
#SIRIUSEvents #MassSpectrometry
Online now - the Review "Decoding human #ChemicalReprogramming: mechanisms and principles" from Hongkui Deng and colleagues.
#SmallMolecules #Plasticity #Pluripotency #Regeneration
authors.elsevier.com/a/1ks7s3S6Gf...
Want to learn about Ometa Flow but only have 49 seconds?
Here you go!
youtu.be/U2aAHK8ysvU?...
#discovery #smallmolecules #metabolomics
A database for large-scale docking and experimental results #modeling #protein #ligand #interaction #prediction #smallmolecules #vhts #gigascale #docking
The impact of Library Size and Scale of Testing on Virtual Screening #modeling #protein #ligand #interaction #prediction #smallmolecules #vhts #gigascale #docking
An Aggregation Advisor for Ligand Discovery #modeling #protein #ligand #interaction #prediction #smallmolecules #vhts #gigascale #docking
Virtual screening. Validated. #modeling #protein #ligand #interaction #prediction #smallmolecules #vhts #gigascale #docking
Have protein-ligand co-folding methods moved beyond memorisation? #drugdesign #folding #protein #ligand #smallmolecules #structure #prediction #deeplearning #benchmark #docking #runsposes #alphafold3 #protenix
Curious about Ometa but not sure where to begin? We've got you covered!
youtu.be/bv46lZJMZgY?...
#metabolomics #massspectrometry #dataanalysis #smallmolecules
Promotional graphic for a blog post showing a graphic representation of the split between small molecules, proteins and oligonucleotides plus the 3D structure of CSD refcode POHPEL.
💡The #FDA approved 50 new drugs in 2024, 64% of which were #SmallMolecules.
Find out more about the novel drug approval trends from the past 5 years and discover the structures of the small molecule drugs that are in the CSD 👉🔗 ccdc-info.com/3WIJWWz
#Pharmaceuticals #ChemSky #BlueskyBiotech
🌟 Join Us at the Agilent Forum Analytik 🌟
Don’t miss Martin Hoffmann’s talk on #SmallMoleculeIdentification with #SIRIUSSoftware.
🗓 12 Feb, 9:40 AM
📍 BOKU Vienna
🎟️ Free attendance—register by 31 Jan!
See you in Vienna!
#AgilentForum #MassSpectrometry #SmallMolecules #SIRIUSEvents
High-quality datasets are key for reliable #MachineLearning in #AnalyticalChemistry!
We explain:
✨ Why diverse datasets matter for SIRIUS
✨ The Importance of representing all #SmallMolecules
✨ Which tools help assessing #DataQuality
bright-giant.com/2025/01/20/m...
#SIRIUSBackground #AI
Just 2 days left of #CSDWrapped!
Did you publish structures in the CSD this year? If so, don't miss out on getting your own personalized graphic showing your top stats for the year! #MoveOverSpotify
#ChemSky #CompChemSky #CrystalStructures #StructuralChemistry #SmallMolecules #Cheminformatics 🧪 🥽
📢Want your own personalized graphic with a summary of the structures you published in the CSD this year (Oct23-Oct24)?
Just reply with "What's my #CSDWrapped?" and tell us your publishing name.
This week only!👀
#ChemSky #CompChemSky #Crystallography #StructuralChemistry #ChemData #SmallMolecules
Novartis acquires the rights to PTC518, a splicing modifier targeting Huntington’s disease, in a $2.9B deal with PTC Thx. Early studies show it reduces mutant huntingtin protein levels effectively. pubmed.ncbi.nlm.nih.gov/39155237/
#HuntingtonsDisease #PharmaNews #DrugDevelopment
#SmallMolecules
Our CSO Jennifer Petter shares her expertise today as facilitator on “RNA as a Drug Target: Breakthroughs and Challenges in Small Molecule Approaches” at the 2024 Medicinal Chemistry Strategy Meeting.
#MedicinalChemistry #SmallMolecules #ExpeditionRNA #BioSky
www.linkedin.com/posts/medici...
