Advertisement · 728 × 90
#
Hashtag
#Spombe
Advertisement · 728 × 90
Imagine standing at a cliff with an ocean view. The ocean is colored orange/yellow hues, and the scruffy grass on the cliff is white. Over the ocean is black text about the Yeast Genetics Meeting June 13-17, 2026 in Pacific Grove CA with #Yeast26. And below the black text is green text yelling "I'm Attending!"

Imagine standing at a cliff with an ocean view. The ocean is colored orange/yellow hues, and the scruffy grass on the cliff is white. Over the ocean is black text about the Yeast Genetics Meeting June 13-17, 2026 in Pacific Grove CA with #Yeast26. And below the black text is green text yelling "I'm Attending!"

Happy to share about #Spombe and #Soctosporus at the #Yeast26 conference in June!!

0 1 0 0
Mating fission yeast cells expressing Myo52-GFP (green), Cdc42-mCherrySW (Magenta) and mTagBFP2 expressed in P-cells (cyan). The cells fail to fuse, as shown by the cyan fusion marker confined to one of cell compartment. Image credit: Sajjita Saha.

Mating fission yeast cells expressing Myo52-GFP (green), Cdc42-mCherrySW (Magenta) and mTagBFP2 expressed in P-cells (cyan). The cells fail to fuse, as shown by the cyan fusion marker confined to one of cell compartment. Image credit: Sajjita Saha.

Polarized growth in #Spombe needs Cdc42, but what role does it play in cell fusion? @sajjitasaha.bsky.social @sophiemartinlab.bsky.social &co show that mitotic polarized growth responds linearly to Cdc42 levels, but mating involves a sharp switch-like response @plosbiology.org 🧪 plos.io/4bvGIhb

3 2 0 0
Mating fission yeast cells expressing Myo52-GFP (green), Cdc42-mCherrySW (Magenta) and mTagBFP2 expressed in P-cells (cyan). The cells fail to fuse, as shown by the cyan fusion marker confined to one of cell compartment. Image credit: Sajjita Saha.

Mating fission yeast cells expressing Myo52-GFP (green), Cdc42-mCherrySW (Magenta) and mTagBFP2 expressed in P-cells (cyan). The cells fail to fuse, as shown by the cyan fusion marker confined to one of cell compartment. Image credit: Sajjita Saha.

Polarized growth in #Spombe needs Cdc42, but what role does it play in cell fusion? @sajjitasaha.bsky.social @sophiemartinlab.bsky.social &co show that mitotic polarized growth responds linearly to Cdc42 levels, but mating involves a sharp switch-like response @plosbiology.org 🧪 plos.io/4bvGIhb

13 2 0 1
Mating fission yeast cells expressing Myo52-GFP (green), Cdc42-mCherrySW (Magenta) and mTagBFP2 expressed in P-cells (cyan). The cells fail to fuse, as shown by the cyan fusion marker confined to one of cell compartment. Image credit: Sajjita Saha.

Mating fission yeast cells expressing Myo52-GFP (green), Cdc42-mCherrySW (Magenta) and mTagBFP2 expressed in P-cells (cyan). The cells fail to fuse, as shown by the cyan fusion marker confined to one of cell compartment. Image credit: Sajjita Saha.

Polarized growth in #Spombe needs Cdc42, but what role does it play in cell fusion? @sajjitasaha.bsky.social @sophiemartinlab.bsky.social &co show that mitotic polarized growth responds linearly to Cdc42 levels, but mating involves a sharp switch-like response @plosbiology.org 🧪 plos.io/4bvGIhb

16 4 0 1
Figure 1

Figure 1

Identification and characterization of Schizosaccharomyces pombe splicing mutants #micropublication #biology #data #caltechlibrary #Spombe #GeneticScreens #PhenotypeData #NewFinding #MaterialsAndReage micropublication.org/journals/biology/micropu...

2 0 0 0
Post image

High resolution mapping of the #actin fusion focus reveals #myosin V-dependent formin transport for aster formation. New study from Valentine Thomas (@valthomas.bsky.social), Sophie Martin (@sophiemartinlab.bsky.social) et al: rupress.org/jcb/article/...

#Cytoskeleton #Microbiology #Spombe #Yeast

4 1 0 0

We set out to understand how subtelomeric #heterochromatin is organized in #Spombe. Subtelomeres are repetitive, variable, and poorly mapped, yet play essential roles in protecting chromosome ends and regulating genome function. (1/n)

1 0 1 0

Excited to share that our work on “Uridylation regulates transcript levels in quiescent yeast cells” was selected for an oral presentation at #yeast2025 in Paris!
Looking forward to sharing our results and discussing RNA regulation in quiescence #quiescence #Spombe #RNAbiology

1 0 0 0

#Telomerase #RNA #Structure #Spombe #FissionYeast

S. pombe telomerase RNA: secondary structure and flexible-scaffold function

Karen McMurdie, Allison N. Peeney, Melissa A. Mefford, Peter Baumann, David C. Zappulla

www.biorxiv.org/content/10.1...

2 0 0 0
Preview
RNase III cleavage signals spread across splice junctions enforce sequential processing of co-hosted snoRNAs Small nucleolar RNAs (snoRNAs) are a class of non-coding RNA molecules whose precursor transcripts are capped and polyadenylated. However, these end modifications are detrimental to snoRNA function an...

#RNaseIII #snoRNA #Spombe

www.biorxiv.org/content/10.1...

1 1 0 0

Excellent stuff! Cheers!
#Yeast #Tools #OpenAI #AI #Scerevisiae #Spombe

3 0 1 0
Preview
A census of RNA-dependent proteins in yeast Understanding the roles of RNA-associated protein complexes is essential to uncovering the mechanisms driving RNA metabolism and its impact on cellular function. Here, we present a comprehensive datas...

Cool!
#RNA #Protein #Scerevisiae #Spombe #Yeast
www.biorxiv.org/content/10.1...

5 0 0 0

We assessed all major heterochromatin domains in #Spombe, performing multiple #genome-wide screens with different #reporter insertions, quantitative readouts, and extensive data normalization. @pombase.bsky.social
(2/n)

2 1 1 0