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2019 Feb.🌱 #Cannabinoids in #cancertreatment: #Therapeuticpotential and #legislation ➡️ learn more: https://pmc.ncbi.nlm.nih.gov/articles/PMC6387667/

#Wissenschaft #science #Studie #Demokratie #Medizin #Politik #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei #Reiche #Huber #Kulturkampf […]

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This review outlines current knowledge on #Tregs, highlighting their role in #ImmuneHomeostasis & self-tolerance, and explores their #TherapeuticPotential across diseases, addressing challenges in tissue-specific targeting. @fudan-university.bsky.social

#STTT: doi.org/10.1038/s413...

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Cannabinoids in cancer treatment: Therapeutic potential and legislation
Barbara Dariš 1,*, Mojca Tancer Verboten 2, Željko Knez 1,3, Polonca Ferk 4
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PMCID: PMC6387667  PMID: 30172249
Abstract
The plant Cannabis sativa L. has been used as an herbal remedy for centuries and is the most important source of phytocannabinoids. The endocannabinoid system (ECS) consists of receptors, endogenous ligands (endocannabinoids) and metabolizing enzymes, and plays an important role in different physiological and pathological processes. Phytocannabinoids and synthetic cannabinoids can interact with the components of ECS or other cellular pathways and thus affect the development/progression of diseases, including cancer. In cancer patients, cannabinoids have primarily been used as a part of palliative care to alleviate pain, relieve nausea and stimulate appetite. In addition, numerous cell culture and animal studies showed antitumor effects of cannabinoids in various cancer types. 

https://pmc.ncbi.nlm.nih.gov/articles/PMC6387667/

Cannabinoids in cancer treatment: Therapeutic potential and legislation Barbara Dariš 1,*, Mojca Tancer Verboten 2, Željko Knez 1,3, Polonca Ferk 4 Author information Article notes Copyright and License information PMCID: PMC6387667 PMID: 30172249 Abstract The plant Cannabis sativa L. has been used as an herbal remedy for centuries and is the most important source of phytocannabinoids. The endocannabinoid system (ECS) consists of receptors, endogenous ligands (endocannabinoids) and metabolizing enzymes, and plays an important role in different physiological and pathological processes. Phytocannabinoids and synthetic cannabinoids can interact with the components of ECS or other cellular pathways and thus affect the development/progression of diseases, including cancer. In cancer patients, cannabinoids have primarily been used as a part of palliative care to alleviate pain, relieve nausea and stimulate appetite. In addition, numerous cell culture and animal studies showed antitumor effects of cannabinoids in various cancer types. https://pmc.ncbi.nlm.nih.gov/articles/PMC6387667/

2019 Feb.🌱 #Cannabinoids in #cancertreatment: #Therapeuticpotential and #legislation ➡️ learn more: https://pmc.ncbi.nlm.nih.gov/articles/PMC6387667/

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Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential This review systematically summarizes dendritic cells (DCs) originating from hematopoietic stem cells, their major subsets (cDC1s, cDC2s, pDCs, moDCs, LCs) and core functions (antigen capture/present...

#Review in #MedComm @wiley.com
Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential doi.org/10.1002/mco2...

#BiologicalFunction #Classification #development #DendriticCell #Origin #TherapeuticPotential

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MicroRNAs in Liver Fibrosis: Unraveling Intercellular Crosstalk and the Regulatory Functions of MicroRNA-223 Announcing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix accumulation, which in turn is driven by activation of hepatic stellate cel...

This commentary summarizes the mechanistic functions of microRNA-223 (#miR223) in #HepaticStellateCell activation and #fibrosis, discusses its #therapeuticpotential and highlights it as a complex but intriguing target for #antifibrotic treatment.

#OpenAccess: bio-integration.org/micrornas-li...

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Therapeutic strategies targeting SREBP transcription factors Mechanism of action underlying SREBP in different diseases and its targeted inhibition for disease prevention and treatment.

This review summarizes the recent findings of #SREBPs mainly in terms of physiologic activation processes, regulatory processes, related diseases, and publicly available #SmallMoleculeInhibitors with #therapeuticpotential.

#OpenAccess: amm-journal.org/index.php/20...

#medsky #medicalresearch

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Vagus nerve stimulation changes brain chemistry, hinting at therapeutic potential A recent study published in Psychophysiology provides new insights into how stimulating the vagus nerve through the ear might influence brain function. Researchers found that a single 30-minute session...

Vagus nerve stimulation changes brain chemistry, hinting at therapeutic potential #Science #HealthandMedicine #Neurology #VagusNerveStimulation #BrainChemistry #TherapeuticPotential

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MOBE: A Breakthrough in Gene Editing MOBE offers the ability to make multiple specific point mutations at once, reducing crosstalk and increasing efficiency.

MOBE: A Breakthrough in Gene Editing

www.rockymountainatheists.ca/post/mobe-a-...

#RockyMountainAtheists #rma #WesternCanadaReason #wecanreason #freedomfromreligion #criticalthinking #skeptics #science
#MOBE #GeneEditing #GeneticResearch #TherapeuticPotential #CRISPR

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