AI helps researchers find antimicrobial peptides in Earth’s harshest habitat Researchers built the Extreme Environment Microbiome Catalog from 78,213 genomes across global extreme habitats, revealing major taxonomic and biosynthetic novelty, including 32,715 representative spe...

AI is unlocking thousands of new antimicrobial peptides from Earth's most extreme environments 🌊🦠 Discover the hidden microbial goldmine: www.news-medical.net/news/2026040... #AntibioticDiscovery #Microbiome @natcomms.nature.com

Identification of Natural-Product Inhibitors of the 2C-Methyl-d-erythritol 4-Phosphate Pathway To tackle the emerging resistance against existing antibiotics, we screened natural-product (NP) libraries against two underexploited target enzymes from the 2C-methyl-d-erythritol 4-phosphate (MEP) p...

Identification of Natural-Product Inhibitors of the 2C-Methyl-d-erythritol 4-Phosphate Pathway

pubs.acs.org/doi/10.1021/... @pubs.acs.org

#ACSMedChemLett #NaturalProducts #AntibioticDiscovery #DrugDiscovery #MedicinalChemistry #MEPPathway #AntimicrobialResistance #InfectiousDiseases #GlobalHealth

Maltose-Conjugated Thiosemicarbazones from Substituted Benzaldehydes: Synthesis and Inhibitory Activity against Gram-(+) and Gram-(−) Bacteria The increasing prevalence of multidrug-resistant bacteria necessitates the development of new antibacterial scaffolds with improved efficacy and safety. Thiosemicarbazones are known for their diverse ...

Maltose-Conjugated Thiosemicarbazones from Substituted Benzaldehydes: Synthesis and Inhibitory Activity against Gram-(+) and Gram-(−) Bacteria
pubs.acs.org/doi/10.1021/...

#KellyChibale #MedicinalChemistry #AntimicrobialResistance #AntibioticDiscovery #InfectiousDiseases #ChemicalBiology

🖥️ How is artificial intelligence being applied to microbiological research?

As part of the Microbial Primers series, @delafuentelab.bsky.social publish a guide on the developments in machine learning (ML) and their applications🦠

#Microbiology #ArtificialIntelligence #AntibioticDiscovery

💊 A new SOIL bacteria antibiotic can KILL superbugs! The arms race against resistance just got a mind-blowing upgrade—are pharma companies listening? #Superbugs #AntibioticDiscovery #NatureJournal #HealthRevolution

A team of scientists from the University of Warwick and Monash University has discovered a powerful new antibiotic hidden inside a bacterium that researchers have studied for more than 70 years.

#AntibioticDiscovery #Superbugs #MedicalResearch #UniversityOfWarwick #MonashUniversity

Infectious Disease 2026: From Emerging Threats to Transformative Solutions Keystone Symposia's Infectious Disease conference series explores emerging infectious disease threats, to endemic and unsolved challenges and innovative vaccine and antibiotic strategies to solve the ...

Journey with us from discovery to #globalhealth solutions in our #InfectiousDisease conference series! Explore emerging breakthroughs in #viralthreats #vaccinology #HIVvaccines #AMR #antibioticdiscovery #tuberculosis & more. +Livestream
keypoint.keystonesymposia.org/home/infecti...

Beneath our boots, a microbial revolution brews: scientists just uncovered hundreds of new soil bacteria—and two potential antibiotics. The dirt isn’t just alive, it’s a pharmacy-in-waiting. #SoilMicrobes #AntibioticDiscovery #MicrobialGoldmine

But even with these limitations, AI could usher in a "second golden age" in antibiotic discovery. And this is critically important — because superbugs aren't waiting for anyone. #AI #AntibioticDiscovery #Superbugs #HealthCrisis #Innovation

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From rare earth mine to petri dish: Amycolatopsis sp. YIM10 gifts us a new GPA antibiotic.

🌐 #Bioprospecting #AntibioticDiscovery #Actinomycetes @ewingt-phd.bsky.social @myribw.bsky.social @oleksandrkashuba.bsky.social @nicksevillaz.bsky.social @manjeet786.bsky.social

A key insight: the discovery of mandimycin & lariocidin. These novel antimicrobial compounds were found by exploring microbial chemical diversity beyond traditional screening methods. #AntibioticDiscovery 2/6

New antibiotic found in soil has potential to fight superbugs Lariocidin is a newly discovered antibiotic from soil bacteria. It targets the bacterial ribosome, defeating resistant infections.

New antibiotic found in soil has potential to fight superbugs: Lariocidin is a newly discovered antibiotic from soil bacteria. It targets the bacterial ribosome, defeating resistant infections.

#AntibioticDiscovery #Lariocidin #SuperbugSolution #SoilMicrobes #EarthDotCom #EarthSnap #Earth

Excited to be in Liverpool at the meeting @biologists.bsky.social celebrating 100 years. Very diverse audience and a great #AMR session organized by @kateduncan.bsky.social! Great first talk from Roger Linington integrating high throughput screening and computational tools for #antibioticDiscovery

Ice Cores as a Source for Antimicrobials: From Bioprospecting to Biodesign | BioDesign Research The golden age has passed for antibiotic discovery, and while some antibiotics are currently in various phases of clinical trials in the United States, many pharmaceutical companies have abandoned ant...

Ice cores: novel antibiotics via synthetic biology. #AntibioticDiscovery
Details: spj.science.org/doi/10.34133/bdr.0024

Discovery of a structural class of antibiotics with explainable deep learning - Nature An explainable deep learning model using a chemical substructure-based approach for the exploration of chemical compound libraries identified structural classes of compounds with antibiotic activity a...

Discovery of a structural class of antibiotics with explainable deep learning #ScientificDiscovery #DeepLearning #AntibioticDiscovery

www.nature.com/articles/s41...

First day of the Duncan lab at @nubiosciences @UniofNewcastle - I think our lab members and actinomycetes are going to be very happy here #antibioticdiscovery #AMR #microbiology #antimicrobialresistance #metabolomics