A virus hiding inside bacteria may help explain colorectal cancer The gut bacterium Bacteroides fragilis has long presented researchers with a paradox. It has been associated with colorectal cancer, yet it also lives quite happily in most healthy people. A study by…

#Virus hiding inside #bacteria may help explain #colorectal #cancer ...

| #Bacteroides | #microbiome | #bacteriophages | #phage | Via @sciencex.bsky.social

Metronidazole is the best treatment for infections caused by bacteroides #metronidazole #bacteroides
... Continue to: youtube.com/shorts/ogtD5...

A virus hiding inside bacteria may help explain colorectal cancer Scientists found an unexpected viral hitchhiker lurking inside a common gut bacterium – and it was twice as prevalent in people with colorectal cancer.

#Virus inside #bacteria may help explain #colorectal #cancer ...

| #Bacteroides | #microbiome | #MicroSky | #infections | #phage | Via @theconversation.com

Metronidazole is the best treatment for infections caused by bacteroides #metronidazole #bacteroides
... Continue to: youtube.com/shorts/ogtD5...

Newly discovered virus linked to colorectal cancer Colorectal cancer is one of the most common types of cancer in the Western world and a leading cause of cancer-related deaths. Age, diet and lifestyle are known risk factors. However, in most cases…

Newly discovered #virus linked to #colorectal #cancer ...

| #gut | #bacteria | #Bacteroides | #bacteriophage | Via @sciencex.bsky.social

U01.03.005 Anaerobes Anaerobes are bacteria that thrive in environments lacking oxygen. They are part of normal flora but can cause disease when introduced into sterile sites. Key anaerobes include Clostridium, Bacteroides, Fusobacterium, and Actinomyces, known for producing foul-smelling infections and gas formation.

Master anaerobic bacteria, their features, and major infections caused by Clostridium, Bacteroides, and others. #Anaerobes #Microbiology #Clostridium #Bacteroides #Fusobacterium #Actinomyces #MedicalEducation #USMLE #Pathology #BacterialMetabolism #ClinicalMicrobiology

Here you can see a crystal structure of the BtuJ2 protein from Bacteroides thetaiotaomicron in complex with cyanocobalamin (PDB code: 9I2L)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #betasheet #bacteroides #xray

A #Bacteroides fragilis protease activates host PAR2 to induce intestinal #pain and #inflammation

www.cell.com/cell-host-mi... #microbiology #immunology #MicroSky #ImmunoSky #IDSky

A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammation Lakemeyer and colleagues analyze the secretome of gut bacteria to identify factors that target host PAR2. They find that the Bacteroides fragilis protease Bfp1 cleaves and activates PAR2, disrupting…

#Bacteroides fragilis was hyped for 15 years as a Treg inducer and anti-inflammatory so much so that biotech companies were founded on it to capitalize on the early data . Now? Oops.

#immunology
#science
#gut
#inflammation

Bacteroides expand the functional versatility of a conserved transcription factor and transcribed DNA to program capsule diversity - Nature Communications Bacteroides strains have multiple operons for biosynthesis of diverse capsular polysaccharides, but most cells express only one operon at a time due to tight regulation of transcription elongation by ...

Jason Saba, Sternberg Awardee: #Bacteroides fragilis varies its cell surface with 8 capsular polysaccharide operons but only expresses 1 polysaccharide at a time using the combination of invertible promoters and a UpxY-UpxZ hierarchical regulatory program
#phages2025 🦠
www.nature.com/articles/s41...

A new perspective on gut microbiota diversity: Study reveals link between cell shape and metabolic function Despite being genetically identical, bacteria can vary considerably in shape and size. Whether these variations affect bacterial function has remained an open question. Researchers at the Helmholtz…

Link between #cell shape and #metabolic function revealed ...

| #gut | #microbiota | #microbes | #Bacteroides | #bacteria | By @helmholtz.de‬ via @sciencex.bsky.social‬

Gut #bacteria and #acetate team up to #cut #fat in mice #without #muscle #loss

Researchers have found a way to #reduce #obesity via #acetate supplement which reduces fat and liver mass in both normal and obese mice, as long as #Bacteroides are present scitechupdates.com/g...

Well done to Cortés Martin et al
#phage #gut #Bacteroides #CrAss
link: www.tandfonline.com/doi/full/10....
@uccresearch.bsky.social

Researchers discover gut bacteria 'weapon' and redirect it toward cancer University of Oklahoma researchers have discovered that some bacteria in the gut have their own unique "weapon system" to compete against other bacteria for dominance. Importantly, there is promising...

Researchers discover #gut #bacteria 'weapon' and redirect it toward #cancer ...

| #microbes | #Bacteroides | #intestines | #toxins | By @ou.edu‬ via @sciencex.bsky.social‬

Hierarchical glycolytic pathways control the carbohydrate utilization regulator in human gut Bacteroides - Nature Communications In this study, Kabonick et. al. reveal how high sugar diets disrupt Bacteroides intestinal fitness via a glycolytic pathway that is hierarchically governed to rapidly alter transcription by controllin...

New microbiome study out! 🦠🍬 The Townsend Lab @getxlab.bsky.social shows how glucose & fructose inhibit Cur, a key regulator in gut Bacteroides.

High-sugar diets = disrupted gut fitness & altered microbe-host dynamics.

Read it 👉 www.nature.com/articles/s41...
#Microbiome #GutHealth #Bacteroides

Novel enzyme breaks down and synthesizes previously unexplored glycans with prebiotic potential Carbohydrate chains, or glycans, are complex sugar-like compounds that play important roles in various biological processes and structures in our bodies. Galactosides are a type of glycan found in pla...

Novel #enzyme breaks down and synthesizes previously unexplored #glycans with prebiotic potential.

#mighymicrobes #Bacteroides #β-galactosidase #Bxy_22780 #α-GalF

phys.org/news/2025-03...

Redirecting

🚀 New Research Alert! 🧠🦠
Our latest study highlights Bacteroides and their extracellular vesicles (EVs) as next-generation psychobiotics, with exciting potential for mental health applications.

🔬 Read more: doi.org/10.1016/j.cr...

#GutBrainAxis #Psychobiotics #Microbiome #Bacteroides

Multi-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by #Bacteroides and Their Extracellular Vesicles

www.sciencedirect.com/science/arti... #MicroSky #microbiota

Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages Background Bacteriophages (phages) and bacteria within the gut microbiome persist in long-term stable coexistence. These interactions are driven by eco-evolutionary dynamics, where bacteria employ a v...

Our recent preprint examining mechanisms that enable Bacteroides phages to persist with their host in the human gut #bacteroides #phage #gut www.biorxiv.org/content/10.1...

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ens aporta evidències sobre una serie de interaccions i comunicacions moleculars en les que participa la vitD amb complicitat amb el microbioma, concretament unes interaccions que depenen del conreu del #Bacteroides #fragilis,

Enrichment and characterization of human associated mucin degrading microbial consortia by sequential passage Abstract. Mucin is a glycoprotein secreted throughout the mammalian gastrointestinal tract that can support endogenous microorganisms in the absence of com

Enrichment and characterization of human associated mucin degrading microbial consortia by sequential passage

-in #FEMS Microbiol Ecol

#Desulfovibrio #Akkermansia #Bacteroides

academic.oup.com/femsec/advan...