Researchers link #AorticValveCalcification to #senescence and epigenetic dysregulation in human VICs, showing that restoring #HistoneAcetylation with SPV106 reverses senescent/calcific phenotypes and reduces calcification. @alfaisaluniversity
#STTT: doi.org/10.1038/s413...
Epigenetics Update - Complex-specific inhibitors for interrogating ATAC histone acetyltransferase complex go.nature.com/49ecEW2
#Epigenetics #ATAC #HistoneAcetylation
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Gain deeper insights into gene regulation; epigenometech.com
Epigenetics Update - Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture bit.ly/43T1JOp
Yohsuke T. Fukai/Kyogo Kawaguchi in Sci Adv
#Epigenetics #Chromatin #HistoneAcetylation
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High-resolution insights without cell sorting; epigenometech.com
Epigenetics Update - Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation bit.ly/490cQIU
Sofia-Iris Bibli in Cell Metab
#Epigenetics #Metabolsim #HistoneAcetylation
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Perfect for cancer, immunology, and aging; epigenometech.com
Epigenetics Update - SOX2 drives esophageal squamous carcinoma by reprogramming lipid metabolism and histone acetylation landscape go.nature.com/3HP7swZ
#Epigenetics #Cancer #HistoneAcetylation #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
Epigenetics Update - Androgens drive SLC1A5-dependent metabolic reprogramming in polycystic ovary syndrome go.nature.com/4oBA0ub
#Epigenetics #PCOS #HistoneAcetylation #HDAC5
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Perfect for cancer, immunology, and aging research; epigenometech.com
Epigenetics Update - RNA polymerase II coordinates histone deacetylation at active promoters bit.ly/4hCExIU
Jackson A. Hoffman and Trevor K. Archer (NIH) writing in Science Advances
#Epigenetics #HistoneAcetylation
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Empower your research with high-res epigenetic insights at epigenome.us
Other great Reviews:
๐ explore the relationship between #histoneacetylation and metabolism
๐ discuss cross-a amyloids
๐ highlight how #DNAnanostructures can be used to install specific PTMs
๐ how #EphReceptors form signaling complexes
And more!