Figure 1 shows brain atrophy & cognitive performance across serum Klotho concentration tertiles. Subplots display Global cognition, Executive function, Delayed recall, & Immediate learning scores vs. (log)VBR. Klotho tertiles: Low (orange), Medium (blue), High (green).
Higher circulating serum #klotho concentrations moderated the adverse association between brain atrophy and cognition in older adults at risk for #AlzheimerDisease but not in younger individuals. ja.ma/4lmyNWs