Recent #outbreaks highlight the risks of #bacterial #meningitis ...
| #infections | #MicroSky | #publichealth | #vaccine | #Neisseria | Via @theconversation.com
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Hashtag
#neisseria
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New research article
Microbiological analysis and whole-genome sequencing of #Neisseria gonorrhoeae from the microbiological failures in the … #zoliflodacin … trial for treatment of uncomplicated urogenital #gonorrhoea
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #STI #AMR #OpenAccess #OA
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New research article
Antimicrobial resistance in bacterial #meningitis caused by #Streptococcus pneumoniae, #Neisseria meningitidis, or #Haemophilus influenzae (2010–24): a systematic review and meta-analysis
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #AMR #OpenAccess #OA
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December cover of The Lancet Microbe
Our December issue is now online:
www.thelancet.com/journals/lan...
Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #Bordetela #pertussis #scabies #Neisseria #Chlamydia #HIV #TB #AMR #phage #Mycoplasma #Ebola
#IDSky #ClinMicro #OA
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First new kind of #drug to target #gonorrhea in decades approved ...
| #infection | #STI | #antibioticresistance | #Neisseria | #bacteria | By @helenbranswell.bsky.social via @statnews.com
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🔬Vaccine innovation against #AMR
BactiVac's funded 115 projects targeting key AMR-relevant pathogens: #Klebsiella #Ecoli #Salmonella #Shigella #Neisseria, #Pseudomonas #Pneumococcus #Staphylococcus & #Streptococcus
#WAAW @wellcometrust.bsky.social @britsocimm.bsky.social @microbiologysociety.org
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Cover of the November issue of The Lancet Microbe
Our November issue is now online:
www.thelancet.com/journals/lan...
Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #HTLV-1 #AMR #Lassa #Neisseria #gonorrhoea #tuberculosis #TB #influenza
#IDSky #ClinMicro #OA
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New research article
Effect of decreasing the frequency of screening for #Neisseria gonorrhoeae and #Chlamydia trachomatis on the incidence of these infections and antimicrobial use among men who have sex with men using #HIV #PrEP in Belgium
www.thelancet.com/journals/lan...
#AMR #OpenAccess #OA
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Scary complications of #gonorrhea ...
| #infection | #Neisseria | #bacteria | #pathogen | #STI | Via @usatoday.com
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New research article
Determining targets for #ceftriaxone resistance detection in #Neisseria gonorrhoeae based on genotype–phenotype data: an observational study
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #AMR #gonorrhoea #gonorrhea #OpenAccess #OA
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#AI producing #antibiotics is promising – but we should NOT get too excited yet ...
| #bacteria | #antibioticresistance | #superbug | #Neisseria | #Staphylococcus | Via @theconversation.com
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#Condoms, #PrEP and #vaccines .. expanding #STI prevention ...
| #gonorrhoea | #STD | #UnitedKingdom | #Neisseria | #bacteria | #infections | Via @theconversation.com
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New research article
Selecting candidate #Neisseria gonorrhoeae strains for oropharyngeal #gonorrhoea human challenge: a genomics-based analysis of clinical isolates
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #MicroSky #CHIM #OpenAccess #OA
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Alaskan Woman’s death from #gonorrhea sparks fears of a new strain ...
| #bacteria | #STI | #Neisseria | #infection | By @edcara.bsky.social via @gizmodo.com
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New incidences of #meningococcal #disease have been detected ...
| #bacteria | #Neisseria | #vaccination | #infection | Via @theconversation.com
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Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by #Neisseria gonorrhoeae via effects on sialic acid metabolism.
Ng exploits type I IFNs to sialylate LOS and evade immunity; blocking IFNs aids bacterial clearance.
www.cell.com/cell-host-mi... #MicroSky
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Cover of The Lancet Microbe's April issue with a "Coloured transmission electron micrograph of Neisseria lactamica undergoing mitotic division".
Our April issue is now online:
www.thelancet.com/journals/lan...
Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #SARS-CoV-2 #COVID-19 #chikungunya #Neisseria #CHIM #mpox #BSI #Ecoli #Klebsiella #Mycoplasma
#IDSky #ClinMicro #OA
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SciTech Chronicles. . . . . . . . .Mar 17th, 2025
bit.ly/stc031725
#dementia #nitrate #Porphyromonas #Neisseria #Lookup #Registration #IETF #gTLD #MIMO #FPA #MRA #SQP #wildfires #mesh #Kinéis #Silvanet #cortical #amygdala #neurobiology #ESR1
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Some very impressive work on #Neisseria #gonorrhoeae
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New research article
Controlled human infection model of #Neisseria lactamica in late pregnancy investigating mother-to-infant transmission in the UK: a single-arm pilot trial
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #OpenAccess #OA
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Top: Organisation of the nap island in Neisseria gonorrhoeae FA1090. Grey arrows, flanking genes (NEIS0808, pseudouridine synthase; NEIS0794, histidyl-tRNA synthase); blue arrows, genes coding for GG-containing peptides; orange arrows, genes predicted to be involved in peptide processing and secretion; green arrow, gene of unknown function; pink boxes, Correia elements. Bottom: Transmission electron microscopy images from bacteria in HEPES (T = 75 min). Some wild-type bacteria appear normal (indicated with arrow numbered 1), with many others having a dense (arrow 2) or very dense (arrow 3) cytoplasm, periplasmic expansions (arrow 4), or appearing as ghost cells (arrow 5). Extracellular vesicles (arrow 6) and released cellular content (arrow 7) are also visible. Periplasmic expansions are not observable in the ΔltgA or ΔnapRABC strains. Cytoplasm condensation appears more homogenous in the ΔltgA mutant.
Programmed cell death distinguishes N. gonorrhoeae & N. meningitidis from other #Neisseria species. @katyponcin.bsky.social &co identify a horizontally acquired genetic island encoding peptides that drive #autolysis & human cell lysis, aiding colonization & disease 🧪 @plosbiology.org plos.io/4aP2om9
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Top: Organisation of the nap island in Neisseria gonorrhoeae FA1090. Grey arrows, flanking genes (NEIS0808, pseudouridine synthase; NEIS0794, histidyl-tRNA synthase); blue arrows, genes coding for GG-containing peptides; orange arrows, genes predicted to be involved in peptide processing and secretion; green arrow, gene of unknown function; pink boxes, Correia elements. Bottom: Transmission electron microscopy images from bacteria in HEPES (T = 75 min). Some wild-type bacteria appear normal (indicated with arrow numbered 1), with many others having a dense (arrow 2) or very dense (arrow 3) cytoplasm, periplasmic expansions (arrow 4), or appearing as ghost cells (arrow 5). Extracellular vesicles (arrow 6) and released cellular content (arrow 7) are also visible. Periplasmic expansions are not observable in the ΔltgA or ΔnapRABC strains. Cytoplasm condensation appears more homogenous in the ΔltgA mutant.
Programmed cell death distinguishes N. gonorrhoeae & N. meningitidis from other #Neisseria species. @katyponcin.bsky.social &co identify a horizontally acquired genetic island encoding peptides that drive #autolysis & human cell lysis, aiding colonization & disease 🧪 @plosbiology.org plos.io/4aP2om9
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Top: Organisation of the nap island in Neisseria gonorrhoeae FA1090. Grey arrows, flanking genes (NEIS0808, pseudouridine synthase; NEIS0794, histidyl-tRNA synthase); blue arrows, genes coding for GG-containing peptides; orange arrows, genes predicted to be involved in peptide processing and secretion; green arrow, gene of unknown function; pink boxes, Correia elements. Bottom: Transmission electron microscopy images from bacteria in HEPES (T = 75 min). Some wild-type bacteria appear normal (indicated with arrow numbered 1), with many others having a dense (arrow 2) or very dense (arrow 3) cytoplasm, periplasmic expansions (arrow 4), or appearing as ghost cells (arrow 5). Extracellular vesicles (arrow 6) and released cellular content (arrow 7) are also visible. Periplasmic expansions are not observable in the ΔltgA or ΔnapRABC strains. Cytoplasm condensation appears more homogenous in the ΔltgA mutant.
Programmed cell death distinguishes N. gonorrhoeae & N. meningitidis from other #Neisseria species. @katyponcin.bsky.social &co identify a horizontally acquired genetic island encoding peptides that drive #autolysis & human cell lysis, aiding colonization & disease 🧪 @plosbiology.org plos.io/4aP2om9
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Pilin variants segregated in mixed microcolonies. wt*red (Ng170) were mixed at a 1:1 ratio with (in rows 1-5) wtpilE24 green (Ng309), wtpilE17 green (Ng308), wtpilE32 green (Ng310), ΔpilEgreen (Ng081), wt*green (Ng105). Scale bar: 10 μm.
#Neisseria gonorrhoeae evades immunity by altering its surface structures. @maierlab.bsky.social &co show that this process also modulates bacterial interactions, driving microcolony diversification, aggregation, colony morphology & #antibiotic tolerance 🧪 @plosbiology.org plos.io/4aN1zdO
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Pilin variants segregated in mixed microcolonies. wt*red (Ng170) were mixed at a 1:1 ratio with (in rows 1-5) wtpilE24 green (Ng309), wtpilE17 green (Ng308), wtpilE32 green (Ng310), ΔpilEgreen (Ng081), wt*green (Ng105). Scale bar: 10 μm.
#Neisseria gonorrhoeae evades immunity by altering its surface structures. @maierlab.bsky.social &co show that this process also modulates bacterial interactions, driving microcolony diversification, aggregation, colony morphology & #antibiotic tolerance 🧪 @plosbiology.org plos.io/4aN1zdO
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Pilin variants segregated in mixed microcolonies. wt*red (Ng170) were mixed at a 1:1 ratio with (in rows 1-5) wtpilE24 green (Ng309), wtpilE17 green (Ng308), wtpilE32 green (Ng310), ΔpilEgreen (Ng081), wt*green (Ng105). Scale bar: 10 μm.
#Neisseria gonorrhoeae evades immunity by altering its surface structures. @maierlab.bsky.social &co show that this process also modulates bacterial interactions, driving microcolony diversification, aggregation, colony morphology & #antibiotic tolerance 🧪 @plosbiology.org plos.io/4aN1zdO
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Oral #microbiome: #Neisseria → supports #cognitive functions. Porphyromonas predicts decline. Nitrate-rich #diet →beneficial oral bacteria →↑ cognitive outcomes. Prevotella assoc. w #APOE4 allele. [open access] bit.ly/4aBIQll bit.ly/3Ebg0Mj
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New research article in The Lancet Microbe
Antimicrobial-resistant #Neisseria gonorrhoeae in Europe in 2020 compared with in 2013 and 2018: a retrospective genomic surveillance study
www.thelancet.com/journals/lan...
#gonorrhoea #gonorrhea #STI #AMR #MicroSky #IDSky #OpenAccess #OA
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