This #STTT review outlines the advanced engineering and combination strategies for #OncolyticViruses to enhance their ability to selectively lyse #MalignantCells and reprogram the #TumorMicroenvironment for #SystemicImmunity.
#OpenAccess: doi.org/10.1038/s413...
This review highlights #OncolyticViruses as emerging #tumor therapeutics and summarizes advances in combining OVs with #immunotherapy—from #CheckpointInhibitors to cellular therapies—showing promise for improved outcomes.
#OpenAccess: doi.org/10.1016/j.ge...
Check out our latest publication on how to deliver #oncolyticviruses to the #centralnervoussystem, by using cells that have a natural capability to move into the brain crossing the blood brain barrier 🧪
www.sciencedirect.com/science/arti...
🔥Hot Off the Press | #OncolyticViruses are gaining momentum: engineered to target tumors, stimulate antitumor immunity, and potentially synergize with immunotherapies. But #delivery, #immunity, and safety still pose big challenges.
🔗Read more: https://ow.ly/E94150X2HiO
#CancerResearch
Comprehensive review published in Cancer Control synthesizing #ClinicalTrials data on #OncolyticViruses (OVs) spanning 2013-2024. Provides an in-depth examination of OVs, highlighting their advancement from investigational modalities to clinical implementation. #ImmunoOncology #Virotherapy
This top-downloaded review summarizes recent progress on combining #OncolyticViruses with #Immunotherapy for #Tumor treatment, offering a powerful strategy to improve #CancerTherapy and patient outcomes. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
🔥Hot Off the Press | Oncolytic viruses (OVs) are gaining momentum: engineered to target tumors, stimulate antitumor immunity, and potentially synergize with immunotherapies. But delivery, immunity, and safety still pose big challenges.
www.thelancet.com/journals/lan...
#OncolyticViruses
Chao and colleagues show an image of glioblastoma (red) treated with CF17 oncolytic virus (green). Image credit: Jianfei Chao.
#MolecularTherapy Oncology's Sept 2025 issue covers new research on #Nanobodies, #OncolyticViruses, #BaseEditing, and #TherapeuticTargets in #Cancer. Check it out today: http://dlvr.it/TN8jsh
#ASGCT
#Medsky🧪 #IDsky #oncosky #pharmsky #Oncolyticviruses (OVs) have been shown to increase the efficacy of #chimericantigenreceptor (CAR) T cells in treating solid tumors. However, their combined effect has been limited by
Most read on OVs!
This review summarizes the latest progress of #OncolyticViruses (OVs) combined with #immunotherapy in #tumor treatment and highlights the future directions of the combination strategies, aiming to promote the clinical application of OVs.
#OpenAccess: buff.ly/jzwlttQ
In a recent episode of @trialstribspod.bsky.social, Professor Kevin Harrington spoke with hosts @prof-nick-james.bsky.social and Dr @hoda-aty.bsky.social to discuss how #OncolyticViruses are used to infect and destroy cancer cells, while also triggering powerful immune responses.
So many scientists are here on bluesky, so either you or someone you know could be interested in submitting a paper in this special issue of "Pharmaceutics" devoted to #oncolyticviruses as drug delivery platforms! (Where I serve as guest editor) 🧪 #medsky #sciencesky
www.mdpi.com/journal/phar...
Recent advances in oncolytic virus combined immunotherapy in tumor treatment
This systematic review summarizes the latest progress of #OncolyticViruses combined with #immunotherapy in #tumor treatment & highlights the future directions of the combination strategies, aiming to promote the clinical application of OVs in tumor therapy. #medsky
#OpenAccess: buff.ly/rJ01ora
Online today 👉 #OncolyticViruses expressing MATEs facilitate target-independent #Tcell activation in tumors
By M. Peter, F. Kühnel & colleagues at Hannover Medical School
🗞️https://doi.org/10.1038/s44321-024-00187-y
Just (re)sharing our latest work on #oncolyticviruses for #glioblastoma, in which we show a powerful immunogenic response to oncolytic HSV1 in an immunocompetent, orthotopic mouse model pubmed.ncbi.nlm.nih.gov/39334370/. Feel free to ask if you want to know more 🧪
Just a quick summary of my research activity.. if you've never heard about #oncolyticviruses (OVs for friends), they are viruses that can be used as anticancer drugs. How is that possible? Well, it turns out that among the many differences between malignant and normal cells/
Targeting cancer cells with modified viruses, OVs selectively destroy tumors & boost immune responses. Effective in melanoma, glioblastoma, & more. A future of hope in oncology! #CancerTreatment #OncolyticViruses #HealthcareInnovation
The cover of the book "Oncolytic Virotherapy: Analysis, Design, Models" by Darshak Bhatt features an illustration of a stylized virus in the center, depicted with complex geometric details. It is set against a background of interconnected cell-like shapes representing tumor tissue, creating a visual of biological intricacy. The background is primarily in dark blue and the design in white, with a yellow accent highlighting the genetic engineering of the virus.
Hello world! Thanks for the friendly connections so far!
Looking forward to explore & share science updates/stories. I share my thesis & cover on Oncolytic virotherapy for those interested in #Synbio #oncolyticviruses, virus-tumor-immune interactions & more.
Link: doi.org/10.33612/diss.859671389
