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She's off to her 2nd round of chemo today! #dogs #pupper #cancersucks #osteosarcoma

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OsteoBites | Targeting EPHA2 with Dual Armored CAR T Cells for Osteosarcoma
OsteoBites | Targeting EPHA2 with Dual Armored CAR T Cells for Osteosarcoma YouTube video by Osteosarcoma: MIB Agents Osteosarcoma Alliance

Thursday, we were joined by vAli Cihan, PhD on OsteoBites to discuss, "Targeting EPHA2 with dual-armored CAR T cells for immunotherapy in pediatric osteosarcoma".

Watch the full episode here: youtube.com/watch?v=1MBS...

#MIBAgents #MakeItBetter #osteosarcoma #OseoBites #podcast

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Donate to Help Róisín Complete Her Cancer Treatment, organized by Heather Sinnott Hello, my name is Heather and I live in Erie, PA. I am the proud owner of Ró… Heather Sinnott needs your support for Help Róisín Complete Her Cancer Treatment

help Roisin!

#dog #cancer #osteosarcoma

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How 3D and Mixed Reality Can Transform Bone Cancer Surgery In the world of musculoskeletal oncology, a specialized orthopedic surgeon acts as both an architect and a demolition expert. When a patient is diagnosed with

New technology is transforming #bonecancer surgery. Yale surgeons are using 3D modeling and #mixedreality to better visualize tumors, plan complex procedures, and improve precision in the operating room.
medicine.yale.edu/cancer/news-...
#osteosarcoma

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OsteoBites | Barcoding metastatic osteosarcoma to identify chemoresistance mechanisms.
OsteoBites | Barcoding metastatic osteosarcoma to identify chemoresistance mechanisms. YouTube video by Osteosarcoma: MIB Agents Osteosarcoma Alliance

Thursday, we were joined by Aafrin Pettiwala, PhD on OsteoBites to discuss, "Identifying mechanisms of chemoresistance in metastatic osteosarcoma using molecular barcoding".

Watch the full episode here: www.youtube.com/watch?v=O3dc...

#MIBAgents #MakeItBetter #osteosarcoma #OsteoBites

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This review shows #glycometabolic reprogramming fuels #Osteosarcoma progression via #glycolysis, mitochondrial dysfunction & immune suppression, highlighting metabolic targeting as a promising strategy to overcome therapy resistance.

#OpenAccess: doi.org/10.1016/j.ge...

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OsteoBites | New insights into shared molecular and genomic features between humans and dogs with OS
OsteoBites | New insights into shared molecular and genomic features between humans and dogs with OS YouTube video by Osteosarcoma: MIB Agents Osteosarcoma Alliance

Thursday, we were joined by Amy LeBlanc, DVM on OsteoBites to discuss, "New insights into shared molecular and genomic features between humans and dogs with OS".

Watch the full episode here: www.youtube.com/watch?v=J_iA...

#MIBAgents #MakeItBetter #osteosarcoma #OsteoBites #podcast

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OsteoBites | Implementing personalized, adaptive therapies in osteosarcoma
OsteoBites | Implementing personalized, adaptive therapies in osteosarcoma YouTube video by Osteosarcoma: MIB Agents Osteosarcoma Alliance

Thursday, we were joined by Corey Weistuch, PhD on OsteoBites to discuss, “Implementing personalized, adaptive therapies in osteosarcoma”.

Watch the full episode here: youtu.be/Tz4qO1LP6lA?...

#MIBAgents #MakeItBetter #osteosarcoma #OsteoBites #podcast

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Bilal Awad: Case Report on Osteosarcoma Recurrence Complicated by Empyema - OncoDaily Bilal Awad: Case Report on Osteosarcoma Recurrence Complicated by Empyema / Bilal Awad, cancer, case report, OncoDaily, Oncology, osteosarcoma

Case Report on Osteosarcoma Recurrence Complicated by Empyema - Bilal Awad

@bilalawad83.bsky.social

oncodaily.com/voices/bilal...

#OncoDaily #Oncology #Cancer #Health #Osteosarcoma #Medicine #MedX #MedTwitter

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Reviewing the role of Nrf2 as a critical mediator of #Chemoradiotherapy resistance in #Osteosarcoma, the mechanisms underlying #OxidativeStress-mediated treatment evasion, and its potential as a #TherapeuticTarget in #BoneCancer treatment.

#OpenAccess: doi.org/10.1016/j.ge...

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Luis Cobos dirige en Las Rozas un concierto solidario contra el osteosarcoma infantil www.giglon.com/todos?idEven... soymadrid.org/madrid/luis-... #LuisCobos #ConciertoSolidario #Osteosarcoma #Madrid

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Alterations in Serum Lipids and Lipoproteins Induced by Neoadjuvant Chemotherapy in Patients with Osteosarcoma around the Knee Joint: A Retrospective Analysis

Alterations in Serum Lipids and Lipoproteins Induced by Neoadjuvant Chemotherapy in Patients with Osteosarcoma around the Knee Joint: A Retrospective Analysis

#NeoadjuvantChemotherapy in #Osteosarcoma elevates #SerumLipids (TC, TG, ApoB, LDL-C, ApoE); pretreatment levels show no prognostic value, but rising Lp(a) correlates with Ki-67, hinting at a potential #biomarker for outcomes.

Read: doi.org/10.1007/s115...

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Iterion Therapeutics Begins Clinical Trial for Innovative Osteosarcoma Treatment Using Tegavivint Iterion Therapeutics has commenced a clinical trial to assess tegavivint, a pioneering drug aimed at treating relapsed osteosarcoma, promising innovative advancements in cancer therapy.

Iterion Therapeutics Begins Clinical Trial for Innovative Osteosarcoma Treatment Using Tegavivint #Houston #US #Osteosarcoma #Iterion_Therapeutics #Tegavivint

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OsteoBites | High throughput characterization of pathobiological responses in OS tumors treated
OsteoBites | High throughput characterization of pathobiological responses in OS tumors treated YouTube video by Osteosarcoma: MIB Agents Osteosarcoma Alliance

Thursday, we were joined on OsteoBites by David Ulmert, MD, PhD.

www.youtube.com/watch?v=8GJK...

#MIBAgents #MakeItBetter #Osteosarcoma #OsteoBites #podcast

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GTSE1+ osteoblasts, enriched in #Metastatic #Osteosarcoma (OS), cross-talk with CD8+ T cells to evade #ImmuneSurveillance via the MIF-(CD74-CXCR4) axis, highlighting GTSE1 as a potential #Biomarker & #TherapeuticTarget.

#OpenAccess: doi.org/10.1016/j.ge...

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Un nuevo modelo predictivo que incluye parámetros nutricionales podria mejorar el tratamiento del osteosarcoma Expertos buscaron construir y validar un modelo de predicción de supervivencia individualizado para pacientes con osteosarcoma  ...

Expertos buscaron construir y validar un modelo de predicción de supervivencia individualizado para pacientes con #osteosarcoma

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Exciting Times in Cancer Research!

Join CURE ID and contribute your report now: cure.ncats.io 

#MIBAgents #MakeItBetter #osteosarcoma #CUREID #research

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"Barnard organization is dedicated to ‘making it better’ for those battling osteosarcoma"

Read Ann Graham's full article with The Vermont Standard here: thevermontstandard.com/barnard-orga...

Thank you, Ann and The Vermont Standard, for Making It Better!

#MIBAgents #MakeItBetter #osteosarcoma

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Next generation dual CAR gamma delta T cells for the treatment of pediatric osteosarcoma
Next generation dual CAR gamma delta T cells for the treatment of pediatric osteosarcoma YouTube video by Osteosarcoma: MIB Agents Osteosarcoma Alliance

Thursday, we were joined by Joseph Skeate, PhD, on OsteoBites to discuss, “Next generation dual-CAR gamma delta T cells for the treatment of pediatric osteosarcoma”.

Watch the full episode here: youtu.be/wiR88fM3Row?...

#MIBAgents #MakeItBetter #osteosarcoma #OsteoBites #podcast

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Scientists identify PKMYT1 as a regulator of #cisplatin sensitivity in #osteosarcoma, showing that PKMYT1‑induced NPM1 S260 phosphorylation enhances #DNARepair and drives #chemoresistance, while combining cisplatin with RP6306 overcomes resistance.

#STTT: doi.org/10.1038/s413...

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Histotricia como técnica de ablación tumoral con conservación ósea en perros con osteosarcoma La histotricia preserva la integridad mecánica tanto del hueso tumoral como del hueso sano y puede ser muy interesante en casos de perros con osteosarcoma ...

Histotricia como técnica de ablación tumoral con conservación ósea en #perros con #osteosarcoma

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Video by @johanstrongcancer Watch on Omni Video

Pain in every step. But we keep moving forward. #cancerfight #chemotherapy #osteosarcoma #cancerjourney #stillfighting

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Very grateful to the German Cancer Aid for granting a new project (PI: team-leader Dr. Jing Li) in our division @dkfz.bsky.social to explore the role(s) of BCAT1 in #osteosarcoma as a prognostic/predictive biomarker and therapeutic target!

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¿Cómo nanoimanes queman el tumor y rehacen hueso a la vez? Nanoimanes de óxido de hierro y vidrio bioactivo: calor contra tumor y superficie que impulsa la regeneración ósea, según Magnetic Medicine. Un equipo de investigación con base en Brasil y colaboració...

¿Cómo nanoimanes queman el tumor y rehacen hueso a la vez? #nanoimanes #cancerderehueso #osteosarcoma #sarcomas #biomateriales #vidriobioactivo #regeneracionosea #hipertermia #nanotecnologia #medicina #ciencia #salud #investigacion #6deenero #felizmartes donporque.com/nanoimanes-a...

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Extraskeletal osteosarcoma harboring ETV6::NTRK3 fusion treated successfully with larotrectinib: a case study - Communications Medicine Skok, Ochsenhofer et al. present the first reported instance of extraskeletal osteosarcoma with an NTRK fusion. The rapid and sustained response to larotrectinib highlights the potential of precision medicine in managing rare and aggressive tumors, emphasizing the importance of molecular profiling to identify actionable targets.

🚨 NEW RESEARCH! ⚕️ 🩺

Skok, Ochsenhofer et al. present a case study of an individual with extraskeletal osteosarcoma harboring a NTRK fusion who was treated successfully with larotrectinib.

https://www.nature.c

@kristijanskok.bsky.social
#Osteosarcoma

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The osteosarcoma tumor microenvironment—immune cells, stromal interactions, inflammatory signals—drives tumor progression and shapes therapy response. New insights highlight emerging clinical strategies.
#Osteosarcoma #TME #Inflammation #OncologyResearch
www.sciencedirect.com/science/arti...

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This review describes various animal models currently used in #Osteosarcoma (OS) research, their characteristics, and advantages & disadvantages, which may help elucidate the mechanisms underlying OS progression.

#OpenAccess: doi.org/10.1016/j.ge...

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Un avance veterinario abre nuevas vías de esperanza para pacientes humanos con osteosarcoma Nuevos análisis de sangre basados en microARN ofrecen esperanza para detectar antes el osteosarcoma, un agresivo cáncer de hueso que afecta a humanos y perros ...

Expertos en medicina veterinaria y humana se han unido para crear análisis de sangre más tempranos y precisos para el cáncer de hueso agresivo conocido como #osteosarcoma

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URGENT!

Find your senators: www.senate.gov/senators/sen...

Every call. Every email. Every voice matters. Let’s give kids a fighting chance.

#MIBAgents #MakeItBetter #osteosarcoma #GiveKidsAChance #ChildhoodCancerAwareness #AdvocateForKids #PassTheBill

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OsteoBites: Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution
OsteoBites: Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution YouTube video by Osteosarcoma: MIB Agents Osteosarcoma Alliance

Thursday, we were joined by Isidro Cortés-Ciriano, PhD, on OsteoBites to discuss, "Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution".

Watch the full episode here: www.youtube.com/watch?v=H1kV...

#MIBAgents #MakeItBetter #osteosarcoma #OsteoBites #podcast

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