All #pediatric #cancers are #rarecancers and there are MANY of them, per @seattlechildrens.org pathologist Dr. Christopher Sande, who focuses on soft tissue #sarcomas. And MANY of these cancers have subtypes. #rarecancersymposium @fredhutch.org #CanSky

Some undifferentiated #sarcomas appear to be responsive to #immunotherapy but reliable #biomarkers are needed. @pawelsobczuk.bsky.social
explains more in his Opinion piece in the #ESMODailyReporter ➡️https://ow.ly/Gr0t50YtqJj

#ESMORareCancers26

Breakthrough in Sarcoma Treatment Immunotherapy improves cancer-free survival by 15%, offering new hope for sarcoma patients.

(2/4) Researchers at @pmresearch-uhn.bsky.social are studying an innovative immunotherapy treatment that may improve outcomes for patients with soft tissue #sarcomas.

🔗: www.uhnresearch.ca/news/breakth...

Las carencias en el abordaje de los sarcomas: “Dar voz a los pacientes es clave para corregir errores estructurales” Los sarcomas siguen siendo poco visibles. Esta realidad dificulta el diagnóstico, incrementa las desigualdades territoriales y limita la investigación

#Pacientes | 👉 Los #sarcomas representan apenas el 1% de todos los #cánceres, pero tienen un gran impacto clínico

¿Cómo nanoimanes queman el tumor y rehacen hueso a la vez? Nanoimanes de óxido de hierro y vidrio bioactivo: calor contra tumor y superficie que impulsa la regeneración ósea, según Magnetic Medicine. Un equipo de investigación con base en Brasil y colaboració...

¿Cómo nanoimanes queman el tumor y rehacen hueso a la vez? #nanoimanes #cancerderehueso #osteosarcoma #sarcomas #biomateriales #vidriobioactivo #regeneracionosea #hipertermia #nanotecnologia #medicina #ciencia #salud #investigacion #6deenero #felizmartes donporque.com/nanoimanes-a...

Neoadjuvant Radiotherapy in Soft Tissue Sarcomas - OncoDaily Neoadjuvant Radiotherapy in Soft Tissue Sarcomas / cancer, OncoDaily, Oncology, radiation oncology, radiotherapy, soft tissue sarcoma radiotherapy, soft

Neoadjuvant Radiotherapy in Soft Tissue Sarcomas

oncodaily.com/oncolibrary/...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #Radiotherapy #Sarcomas

Histopathological Response After Neoadjuvant Chemotherapy in Soft-Tissue Sarcomas This secondary analysis of a randomized clinical trial evaluates the histopathological features associated with risk of recurrence that can be used to estimate outcomes in patients with high-risk soft...

Histopathological Response After Neoadjuvant #Chemotherapy for High-Risk Soft-Tissue #Sarcomas: A Secondary Analysis of a Randomized Clinical Trial jamanetwork.com/journals/jam... #hvhebron #ap [Text complet] @jamanetworkopen.com

In case you missed it, the first webinar of our pediatric sarcoma series is now available on YouTube! Hear from Dr. Damon R. Reed, Dr. Katherine A. Janeway, and Care Partner and Advocate Jenny Sage as they discuss what makes pediatric #sarcomas unique. Link in bio.

#curesarcoma #pediatricsarcoma

Join us for our first Pediatric Sarcoma Webinar, happening Sept. 24 from 5–6 PM EST! Hear from top experts and Care Partner and Advocate, Jenny Sage, on treatment, care, and what makes pediatric #sarcomas unique. Save your spot through the link in bio!

#curesarcoma #pediatricsarcoma

Patient-derived tumoroids from CIC::DUX4 rearranged sarcoma identify MCL1 as a therapeutic target - Nature Communications Despite their differences, the rarer sarcoma CIC::DUX4 sarcoma (CDS) is typically treated with therapies developed for Ewing Sarcoma (EwS) with limited success. Here, the authors develop a co-clinical...

Great back-to-back papers in @natcomms.nature.com
tinyurl.com/3dp98bke
tinyurl.com/wy9ychb2
on MCL1 as a novel therapeutic target in CIC::DUX #sarcomas

These cancers remain challenging (tinyurl.com/kz4h8rws) but these studies spark hope! Glad that our division @dkfz.bsky.social could contribute!

Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas - Nature Communications Sarcomas are a group of mesenchymal malignancies which are molecularly heterogeneous. Here, the authors develop an in vivo muscle electroporation system for gene delivery to generate distinct subtypes...

Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk #sarcomas

www.nature.com/articles/s41...

🔬UPO, @unisevilla.bsky.social y @hospitaluvrocio.bsky.social trabajan en una ambiciosa investigación para detectar #biomarcadores clave en #sarcomas, un tipo de cáncer poco frecuente y complejo.

Alianza que abre la puerta a una medicina + precisa, rápida y esperanzadora.

www.upo.es/diario/cienc...

#PublicEducation on #sarcomas can be fun! 😃 #facialkexpressions #CannotHideHit #HappyMonday #CUHKSarcoma

youtu.be/XesQlcQPMOY?...

#Sarcomas are rare cancers with 100+ subtypes, and the initial symptoms can surprise you. Join us thru July for a journey through the sarcoma experience, and learn about the global sarcoma community that is working together, making a difference!

#SarcomaAwarenessMonth2025
2/2

Thanks @liferaftgroup.bsky.social for opportunity to share some key #GIST updates from #ASCO25 w/ wider patients' community 🌎 through this webinar last week.

@srothschild @cuhkmedicine.bsky.social @GISTNetwork @ctosociety #DrugDevelopment #sarcomas #CUHKSarcoma

youtu.be/uoZULT8YlPU?...

Nanopore whole-genome sequencing of human sarcomas - EGA European Genome-Phenome Archive We performed single and multi-region nanopore whole-genome sequencing on human sarcoma samples from adult and paediatric patients.

So, first, we generated matched illumina (~120x) and @nanoporetech.com (~50x) for 99 tumours with complex rearrangement profiles: 57 diverse soft tissue #sarcomas, 28 #osteosarcomas and 14 #glioblastomas. All long-read data are accessible via the EGA:
ega-archive.org/studies/EGAS...

(2/2) Their projects advance research on #stress and the brain, healthy #aging, fall prevention, rare #sarcomas, and #BreastCancer treatment resistance.

💉🔬Oncología de Son Espases ha participado en la Guía SEOM-GEIS de 2024 para el manejo de los sarcomas de partes blandas www.infosalut.com/es/investigacio/estudis-... https://doi.org/10.1007/s12094-024-03842-5

#GuiaSEOMGEIS2024 #oncología #sarcomasdepartesblandas #sarcomas

April Issue: Challenges, Treatment Strategies, and Surgical Techniques in the Management of Spermatic Cord #Sarcomas
rdcu.be/ehe13

Evalúan una nueva formulación gel de cisplatino para el tratamiento de sarcomas caninos Los sarcomas de tejidos blandos son un grupo de tumores cutáneos propensos a la recurrencia local si no se extirpan quirúrgicamente de forma adecuada ...

Los #sarcomas de tejidos blandos son un grupo heterogéneo de #tumores mesenquimales que suelen aparecer en la #piel o el tejido subcutáneo de los #perros

Evalúan una nueva formulación gel de cisplatino para el tratamiento de sarcomas caninos Los sarcomas de tejidos blandos son un grupo de tumores cutáneos propensos a la recurrencia local si no se extirpan quirúrgicamente de forma adecuada ...

Los #sarcomas de tejidos blandos son un grupo de #tumores cutáneos propensos a la recurrencia local si no se extirpan quirúrgicamente de forma adecuada

Evalúan una nueva formulación gel de cisplatino para el tratamiento de sarcomas caninos Los sarcomas de tejidos blandos son un grupo de tumores cutáneos propensos a la recurrencia local si no se extirpan quirúrgicamente de forma adecuada ...

Evalúan una nueva formulación gel de #cisplatino para el tratamiento de #sarcomas #caninos

We are kicking off @myesmo.bsky.social #ESMORareCancers25 in Lugano 🇨🇭 this morning! Looking forward to 3 days of interactions with experts in #sarcomas and other #rarediseases from around the 🌎. #CUHKSarcoma #CTOSTweeTOS

Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

🥳 Excited to share our new paper on #pediatric #sarcomas! Restoring p53 tumor suppressor activity offers a promising approach to target aggressive, cancer stem-like cells in these childhood tumors:

rdcu.be/d2ufo

@MUNI @FNUSA-ICRC @agentura_azvcr (not yet here)

🧵1/n👇

Interesting data from India by Jyoti Bajpai and colleagues on #AYA with bone #sarcomas emphasizing the role of treatment according to existing protocols and timely referrals for fertility preservation before starting the intensive chemotherapy trajectories.

pubmed.ncbi.nlm.nih.gov/39297373/