Slide from a talk showing big science projects from physics: James Webb ($10B), CERN ($5B), Perseverance Mars lander ($2.7B), Hubble ($10B), Expanded Very Large Array ($2B). Below:,Life Science: Human Genome Project ($2.7B), Protein Data Bank ($10B). (Note that PDB is not a coordinated centralized funding mechanism, but an organic effort, collecting $10B worth of work)
Great talk by @erika-alden.bsky.social at #Scverse2025 on what's the next PDB? What is PDB? It's the protein database that underlies the recent protein folding Nobel Prize and billions in recent biotech investments. Unlike other big science, PDB was an organic effort of $10B of separate grants.