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Posts by Jennifer Vandooren

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PhD-positie – Onderzoek naar intracellulaire metalloproteasen bij macrofaag-gemedieerde ontsteking Ben jij gefascineerd door het immuunsysteem? Wil je je verdiepen in de wereld van immuuncelproteasen en hun rol bij inflammatie? Wij zoeken een sterk gemotiveerde persoon om ons onderzoeksteam te vers...

πŸ“’ We're hiring! πŸ”¬

Fascinated by the immune system? Eager to study immune cell proteases and their role in inflammation? We're looking for a highly motivated researcher to join our team!

πŸ”—https://www.kuleuven.be/personeel/jobsite/jobs/60494943

#Immunology #Immunosky #AcademicJobs #PhDjobs

9 months ago 9 6 0 0
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🌟 Proud supervisor 🌟- Two days ago, I had the pleasure of attending the Belgian MS Research Day in Leuven with my PhD researchers, Eline and Febe, who gave impressive presentations and truly shone.

#MSResearch #PhDLife #ProudSupervisor #ScienceCommunication

9 months ago 10 0 0 0

We just published one of our #research protocols as a STAR protocol 🌟.

Check out our protocol if you are interested in #macrophage #proteases! πŸ”¬βœ¨

#AcademicTwitter #OpenScience #researchmethods #immunosky

10 months ago 4 1 0 0
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Protocol to generate human monocyte-derived macrophages in the absence of exogenous proteases and protease inhibitors to study proteolysis Investigating proteases and protease inhibitors produced and secreted by primary cells is complicated by the presence of exogenous ones in cell culture medium containing fetal bovine serum. With this protocol, we generate human monocyte-derived macrophages in the absence of exogenous proteases and protease inhibitors by using a serum replacement for the final 24 h of macrophage culture. We describe steps for seeding and differentiating monocytes into macrophages. We then detail procedures for ma...

Protocol to generate human monocyte-derived macrophages in the absence of exogenous proteases and protease inhibitors to study proteolysis #protocol #starprotocols #cellpress

11 months ago 2 1 0 1
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The 13th General Meeting of the International Proteolysis Society will be held in BΓΊsios, Brazil Oct 26-30, 2025. Training workshops will be held at the Instituto Oswaldo Cruz Oct 23-23. Register now! Links below.

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11 months ago 7 8 1 1

Not long after I started my lab, a prominent scientist told me it was β€œimpossible” to be a successful PI and a mother

Don’t ever let the naysayers tell you it can’t be done - of course it can!

#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids πŸ₯°

11 months ago 266 44 5 5
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Great day at the #yBIS meeting today!

⭐️ Presenting as a keynote speaker

⭐️ Witnessing Febe and Eline presenting at the poster session #proudPI

⭐️ Febe’s first conference and poster presentation

⭐️ Meeting inspiring young immunologists, a great atmosphere and superb organization

#AcademicLife

11 months ago 1 1 0 0
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The final program for the #yBIS2025 meeting is here:

Check out what #Belgian #ECR #Immunologists have to present.

We are looking forward to next Friday

11 months ago 1 3 1 0
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We’re thrilled to welcome @jennvandooren.bsky.social (KULAK, BE) as keynote #speaker at the yBIS 2025 Annual Meeting!

Her research dives into how #leukocyte proteases shape #immunity, with a special focus on #neutrophils and #macrophages

#yBIS2025 #ImmunoSky #EarlyResearchers

11 months ago 2 1 0 0
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#Updated program

Unfortunately, John McKendrick from UGent cannot present at #yBIS2025.
Jennifer Vandooren ( @kuleuvenuniversity.bsky.social) will share her research on the 9th of May on leukocyte proteases as immune mediators.

1 year ago 2 1 0 0
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I'm super happy that our story is now published!
πŸ“– www.science.org/doi/10.1126/...
But what changed compared to the original preprint?

Also, I feel i should post Movie 1 πŸŽ₯, that inspired the cover. Back when I did the original bluesky thread, movies were not available.

1 year ago 215 68 7 9
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Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression @cp-immunity.bsky.social
www.cell.com/immunity/ful...

1 year ago 21 9 1 0
microscope image of a postnatal mouse brain showing the entry point of blood vessel into the brain - fibroblasts (yellow: S100a6) form a layer at the brain's edge (meninges) and surround the blood vessel. Astrocyte endfeet (magenta, GFAP) form a layer at the brain's edge, apposed to the fibroblasts. Image also shows macrophages (cyan; CD206) and cell nuclei (DAPI, blue)

microscope image of a postnatal mouse brain showing the entry point of blood vessel into the brain - fibroblasts (yellow: S100a6) form a layer at the brain's edge (meninges) and surround the blood vessel. Astrocyte endfeet (magenta, GFAP) form a layer at the brain's edge, apposed to the fibroblasts. Image also shows macrophages (cyan; CD206) and cell nuclei (DAPI, blue)

I was imaging this weekend, took this image because it was beautiful to me, the blood vessels, fibroblasts, astrocytes, & macrophages as steadfast guardians at the brain's edges. Cheers to the 'guardians' of all that is important. ❀️

1 year ago 100 7 2 0
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Honoured to receive funding from the Charcot Foundation for our research on #proteolysis by myelin-challenged #macrophages in #MultipleSclerosis!

πŸ‘‰ www.fondation-charcot.org/en/winners/2...

Excited to advance our #Research and looking forward to the discoveries ahead! πŸ”¬πŸ€©

#WomenInSTEM #ImmunoSky

1 year ago 13 1 1 0

#PreprintClub is now on Bluesky!

Who are we and what are we doing? We are a group of enthusiastic scientists that gather together once a week to discuss fresh preprints in the field of #immunology. 🦠🧬

1 year ago 54 22 1 1
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GFAP expressing #astrocytes in orange, IBA1 positive microglia in blue. Images from unsectioned rat hemisphere. #lightsheet #microscopy at #Vanderbilt

1 year ago 75 15 4 0
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Interested in a PhD or MS in Neuroscience?

PhD applications are due Dec 1st!
No GREs
We value and welcome diversity!

Apply to @AlbanyMed! πŸ‘‡

#NeuroPhD #phdlife #NeurosciencePHD

1 year ago 5 5 1 0
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If you are looking for an exciting PhD in the fields of #ChemicalBiology, #ChemBio, #Proteomics and #Immunology, in a dynamic group with an inspiring PI, Madeline Kavanagh has an open position for a PhD project involving synthesis, chemical proteomics and immunology. drive.google.com/file/d/11Mhm...

1 year ago 11 8 0 0
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The antibodies don’t work! The race to rid labs of molecules that ruin experiments Poorly performing antibodies have plagued biomedical sciences for decades. Several fresh initiatives hope to change this.

"The antibodies don’t work!"

We, like many labs, have faced issues with bad antibodies cell.com/cell-stem-ce...

Great to see that some are tackling this problem head-on!

Read more about their solutions:
www.nature.com/articles/d41...

#ImmunoSky #Metaresearch #Openscience

1 year ago 53 17 3 4

Great community! Can you add me? My lab 🫢🏻 proteolysis in the ECM!

1 year ago 2 0 1 0

Welcome to BlueSky @jexpmed.bsky.social!

Looking forward to authors being able to provide their πŸ¦‹ contact details when submitting manuscripts.

1 year ago 19 8 1 1
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Human monocyte-derived macrophages shift subcellular metalloprotease activity depending on their activation state Natural sciences; Biological sciences; Immunology; Immune response

Check out our latest research πŸ‘‡πŸ§ͺπŸ”¬πŸ‘©πŸ»β€πŸ”¬! We studied how protease activity changes in human macrophages upon their activation. We uncovered that IL-4 results in the uptake of matrix metalloprotease-9 (MMP-9) and its nuclear localization. #Macrophages #Immunology #AcademicSky

www.cell.com/iscience/ful...

1 year ago 3 0 0 0
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Some nice neurons: Khc[8], Rtnl1::YFP, stained for tubulin and with mitoTracker. Happy weekend!

1 year ago 29 6 0 1
IT support broken laptop bricked

IT support broken laptop bricked

Your IT support and a user brings in their laptop for repair… first thoughts?

1 year ago 2 1 1 0

😲 how?

1 year ago 0 0 0 0
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1 year ago 331 190 39 23
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