Assembly and phospho-regulatory mechanisms of the budding yeast outer #kinetochore KMN complex. New study from Noah N. Turner (@noahnturner.bsky.social), David Barford and colleagues @mrclmb.ac.uk:
rupress.org/jcb/article/...
#CellDivision #StructuralBiology #kinetochores #centromeres #cryoEM
Posts by Stephen McLaughlin
Three-year funded postdoctoral fellowship for scientists returning after a 12-month career break, deadline May 17, 2026.
The LMB is proud to launch the Career Returner Fellowship, a three-year, fully funded postdoc placement for scientists who have had a career break of over 1 year.
Applications are open now!
More details: mrclmb.ac.uk/careers-and-...
Please share this post with anyone who may be interested!
Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍.
www.science.org/doi/10.1126/...
www.youtube.com/watch?v=gFE4...
📣 Physicists and engineers: apply your experimental skills to biology! Join the group of Katerina Naydenova @imprs-lm.bsky.social for a #PhD to develop new technologies that enable answering fundamental biological questions. Apply NOW!
🔍 Want to uncover how proteolytic enzymes in the ubiquitin system work—and exploit those insights for novel therapeutic approaches? Apply to the Gersch Lab @maltegersch.bsky.social at @imprs-lm.bsky.social.
#proteolysis #ubiquitin #biochemistry #proteinchemistry
3D molecular model showing a complex protein structure with blue, green, pink, and gray regions bound to a twisted blue DNA strand.
📣 Fully funded PhD position available!
Join @suyangzhang.bsky.social’s group to uncover how human cells coordinate RNA transcription and splicing. You’ll use biochemical, structural & cellular approaches, including #cryoEM.
Apply by 14th April.
More details: mrclmb.ac.uk/careers-and-...
#PhDposition
We are RECRUITING for maternity cover for our NMR facility at the UCL School of Pharmacy - expected from April until February. Come and join us! Details below, feel free to reach out to me informally for more information. Closing date *9 March*.
We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social
Please get in touch if you have any questions.
www.nature.com/naturecareer...
Our latest preprint: Together with the team of Jan Löwe, @danieltamarit.bsky.social and many others we discovered and characterized several Asgard tubulin genes and propose that microtubule architecture and dynamics evolved in Asgard archaea prior to eukaryogenesis
www.biorxiv.org/content/10.6...
Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳
mrc.tal.net/vx/mobile-0/...
How did life arise from simple chemical building blocks?
New #LMBResearch led by @edogia.bsky.social in @philholliger.bsky.social group has identified a small self-replicating ribozyme that could be the answer.
Read more: mrclmb.ac.uk/news-events/...
Suyang Zhang smiles in front of a blurred laboratory background
Exciting opportunity for a #postdoc to join @suyangzhang.bsky.social’s group in the LMB Structural Studies Division to investigate co-transcriptional splicing using cryo-EM and biochemistry.
Read more: www.nature.com/naturecareer...
Apply by 11 FEB
#PostdocJobs #ScienceJobs
Are you interested in finding out how biological questions can be investigated with a range of molecular techniques? Find out how the MRC-LMB facilities tackle problems here:
www.youtube.com/playlist?lis...
Excited to share our latest work on dissecting the mechanism of processive telomeric DNA synthesis by telomerase. Led by amazing PhD student Sebastian Balch in collaboration with lab members,@automnenine.bsky.social @rachael-kretsch.bsky.social,@rdaslab.bsky.social.
www.nature.com/articles/s41...
🚨Postdoc opportunity🚨Our lab at MRC-LMB Cambridge is recruting a postdoc to study transcription-coupled splicing using cryoEM and endogenous isolation! 🔬 🧬
Please feel free to get in touch directly #postdoc #cryoEM #biochemistry #splicing
Apply here by 11 Feb
www.nature.com/naturecareer...
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025
Want to join the LMB as a PhD student in October 2026?
You’ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.
Thanks to the speakers and all who attended our Next Generation Biophysics Symposium. We now looking forward to the 10th Symposium on 16th September 2026. Here is a link to catch up on what happened in this year's
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Excellent #postdoc opportunity available in @sjorsscheres.bsky.social’ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software.
www.nature.com/naturecareer...
Apply by 25 NOV
#PostdocJobs #ScienceJobs
Our lab @mrclmb.bsky.social in Cambridge is seeking a passionate PhD student to explore transcription-coupled splicing! Join our team for an exciting project to understand human gene regulation 🧬 Feel free to get in touch directly #PhD #cryoEM #biochemistry
www2.mrc-lmb.cam.ac.uk/students/int...
I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...
Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025
Considering a PhD in molecular biology?
Make sure to check out the projects on offer at the LMB!
www2.mrc-lmb.cam.ac.uk/students/int...
General applications by 2nd DEC.
US Gates Scholarship applications by 15th OCT.
#PhD
Is that a pointer, looks more like a jedi sword!
Excited that we are only two weeks away for our Next Generation Biophysics Symposium 2025. We have a fantastic line-up of speakers. Registration is closing soon. Come in person or view on-line
#Biophysics #SingleMolecule #CryoEM #nmr #proteindynamics
Carol Robinson on Desert Island Discs - have a listen friends: www.bbc.co.uk/sounds/play/...
An inspirational scientist & friend. An example of combining scientific excellence, courage, hard work and really importantly; kindness. (Yes I’m biased, but it’s true nevertheless)
@kavlioxford.bsky.social
Sofia Lövestam's vault structure is now online in Structure @cellpress.bsky.social. 🥳
How beautifully explorative is #cryoEM! We never planned to do this. The vaults just came down with #amyloids from human brain tissue, and Sofia decided to have a closer look.
www.cell.com/structure/fu...
We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).