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⭐Confirmed: Emilia Mellado as a #PYFF9 speaker!
A microbiologist at the Instituto de Salud Carlos III leading research on #fungal #pathogens like Aspergillus and #antifungal #resistance, work with major impact on infectious disease science.
Don’t miss her talk at #PYFF9 #Valencia2026

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New review article

WHO assessment of the preclinical #antifungal pipeline: evaluating innovation and preparedness in the face of emerging fungal threats

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #MycoSky #OpenAccess #OA

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UK Antimicrobial Registry logo, plus info about new drugs.
www.abdn.ac.uk/ukar

UK Antimicrobial Registry logo, plus info about new drugs. www.abdn.ac.uk/ukar

Our UK Antimicrobial Registry is expanding its focus.
From April, eligible study drugs include #antifungal agents, as well as #antibiotics.
See www.abdn.ac.uk/ukar for information how to get involved.

@uoaepi.bsky.social

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#SIF
Geldanamycin shows strong antifungal action against drug-resistant Aspergillus terreus by disrupting heat shock proteins. A potential dual therapy for infection & cancer.
Details: www.maxapress.com/article/doi/10.48130/sif...
#Aspergillus #Antifungal

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Hydrophobicity, UV resistance, and antioxidant properties of carnauba wax-reinforced CG bio-polymer film

Hydrophobicity, UV resistance, and antioxidant properties of carnauba wax-reinforced CG bio-polymer film

This Open Chemistry study investigated the phytochemistry, #Antioxidant & #Antifungal efficacy of three essential oils, highlighting them as bio-based alternatives to #SyntheticFungicides against postharvest apple pathogens.
#OpenAccess: doi.org/10.1515/chem...

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Green-synthesized silver nanoparticles of Cinnamomum zeylanicum and their biological activities

Green-synthesized silver nanoparticles of Cinnamomum zeylanicum and their biological activities

This Open Chemistry study reports the synthesis and characterization of #SilverNanoparticles (#AgNPs) of Cinnamomum zeylanicum bark extract and demonstrates their potential #AntiBacterial, #AntiFungal, and #AntiLeishmanial efficacy.
#OpenAccess: doi.org/10.1515/chem...

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Top: FK506-resistant strains isolated from the Mucor circinelloides complex. Phenotypic analysis of FK506-resistant isolates in Mucor janssenii CBS185.68 (PS1), Mucor bainieri CBS293.63 (PS3), and Mucor atramentarius CBS202.28 (PS6). WT, wild-type; M, mendelian mutant; E, epimutant. Bottom: Schematic overview of epigenetic silencing contributing to antifungal resistance in Mucor species. fkbA expression enables FKBP12 production and FK506 sensitivity (yeast-like morphology). Epigenetic silencing of fkbA via RNAi and/or heterochromatin leads to FK506 resistance and hyphal growth. Generated with BioRender.com.

Top: FK506-resistant strains isolated from the Mucor circinelloides complex. Phenotypic analysis of FK506-resistant isolates in Mucor janssenii CBS185.68 (PS1), Mucor bainieri CBS293.63 (PS3), and Mucor atramentarius CBS202.28 (PS6). WT, wild-type; M, mendelian mutant; E, epimutant. Bottom: Schematic overview of epigenetic silencing contributing to antifungal resistance in Mucor species. fkbA expression enables FKBP12 production and FK506 sensitivity (yeast-like morphology). Epigenetic silencing of fkbA via RNAi and/or heterochromatin leads to FK506 resistance and hyphal growth. Generated with BioRender.com.

#Antifungal resistance is a global threat, but epigenetic mechanisms drive rapid, reversible adaptation in fungi. This study shows that #RNAi or #heterochromatin driven #epimutations transiently silence the gene fkbA to confer FK506 #tacrolimus resistance in #Mucor @plosbiology.org 🧪 plos.io/4qdttWc

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Top: FK506-resistant strains isolated from the Mucor circinelloides complex. Phenotypic analysis of FK506-resistant isolates in Mucor janssenii CBS185.68 (PS1), Mucor bainieri CBS293.63 (PS3), and Mucor atramentarius CBS202.28 (PS6). WT, wild-type; M, mendelian mutant; E, epimutant. Bottom: Schematic overview of epigenetic silencing contributing to antifungal resistance in Mucor species. fkbA expression enables FKBP12 production and FK506 sensitivity (yeast-like morphology). Epigenetic silencing of fkbA via RNAi and/or heterochromatin leads to FK506 resistance and hyphal growth. Generated with BioRender.com.

Top: FK506-resistant strains isolated from the Mucor circinelloides complex. Phenotypic analysis of FK506-resistant isolates in Mucor janssenii CBS185.68 (PS1), Mucor bainieri CBS293.63 (PS3), and Mucor atramentarius CBS202.28 (PS6). WT, wild-type; M, mendelian mutant; E, epimutant. Bottom: Schematic overview of epigenetic silencing contributing to antifungal resistance in Mucor species. fkbA expression enables FKBP12 production and FK506 sensitivity (yeast-like morphology). Epigenetic silencing of fkbA via RNAi and/or heterochromatin leads to FK506 resistance and hyphal growth. Generated with BioRender.com.

#Antifungal resistance is a global threat, but epigenetic mechanisms drive rapid, reversible adaptation in fungi. This study shows that #RNAi or #heterochromatin driven #epimutations transiently silence the gene fkbA to confer FK506 #tacrolimus resistance in #Mucor @plosbiology.org 🧪 plos.io/4qdttWc

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Top: FK506-resistant strains isolated from the Mucor circinelloides complex. Phenotypic analysis of FK506-resistant isolates in Mucor janssenii CBS185.68 (PS1), Mucor bainieri CBS293.63 (PS3), and Mucor atramentarius CBS202.28 (PS6). WT, wild-type; M, mendelian mutant; E, epimutant. Bottom: Schematic overview of epigenetic silencing contributing to antifungal resistance in Mucor species. fkbA expression enables FKBP12 production and FK506 sensitivity (yeast-like morphology). Epigenetic silencing of fkbA via RNAi and/or heterochromatin leads to FK506 resistance and hyphal growth. Generated with BioRender.com.

Top: FK506-resistant strains isolated from the Mucor circinelloides complex. Phenotypic analysis of FK506-resistant isolates in Mucor janssenii CBS185.68 (PS1), Mucor bainieri CBS293.63 (PS3), and Mucor atramentarius CBS202.28 (PS6). WT, wild-type; M, mendelian mutant; E, epimutant. Bottom: Schematic overview of epigenetic silencing contributing to antifungal resistance in Mucor species. fkbA expression enables FKBP12 production and FK506 sensitivity (yeast-like morphology). Epigenetic silencing of fkbA via RNAi and/or heterochromatin leads to FK506 resistance and hyphal growth. Generated with BioRender.com.

#Antifungal resistance is a global threat, but epigenetic mechanisms drive rapid, reversible adaptation in fungi. This study shows that #RNAi or #heterochromatin driven #epimutations transiently silence the gene fkbA to confer FK506 #tacrolimus resistance in #Mucor @plosbiology.org 🧪 plos.io/4qdttWc

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Discover the sub-collection of #antifungal resistant strains @BCCM/IHEM:

• >80 well-characterized strains from yeasts, dermatophytes & Aspergillus species
• Documented resistance to azole drugs, echinocandins, terbinafine & amphotericin B
• Validated with EUCAST reference method

bccm.belspo.be

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Dissecting the biosynthesis, regulation, and metabolic engineering of steroidal glycoalkaloids in tomato This mini-review synthesizes recent advances in the biosynthesis and regulation of tomato steroidal glycoalkaloids and discusses the potential applications of metabolic engineering for targeted modul...

🍅 It's #TomatoTuesday on Thursday!
🍅This time,🍅we join🍅Chen et al. as they investigate the #biosynthesis, regulation, and metabolic #engineering of #antifungal, #antibacterial,🍅and #anticancer compounds in #tomato.🍅
🍅 doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantSci #SynBio #Pharming

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Prokaryotics and Basilea Team Up to Combat Severe Fungal Infections with Innovative Antifungals Prokaryotics and Basilea join forces to address the urgent need for a new broad-spectrum antifungal agent to tackle severe invasive infections caused by drug-resistant pathogens.

Prokaryotics and Basilea Team Up to Combat Severe Fungal Infections with Innovative Antifungals #United_States #Prokaryotics #Basilea #Antifungal #Union,_NJ

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Anyone here have experience with topical #butenafine (Lotrimin Ultra) on #dogs, especially if the dog is going to lick off a bunch of it? My wife was using an #antifungal wipe. Then we tried #Lamisil#terbinafine & the wipes. Then I added hydrocortisone, hoping to make him less likely to lick…

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Antifungal resistance is making thrush hard to treat – here’s why Infections are becoming harder to treat because the fungi are adapting to survive antifungal drugs – but this isn’t happening by chance.

#Antifungal resistance is making #thrush hard to treat ...

| #fungi | #infection | #Candida | #yeast | #drugs | Via @theconversation.com

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Epigenetics Update - Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance bit.ly/3XupYPn

Robin C. Allshire/Alison L. Pidoux (Uni. Edinburgh) in EMBO J

#Epigenetics #Chromatin #AntiFungal
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High-resolution insights without cell sorting; epigenometech.com

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Evaluation of the Antifungal Effect of Carvacrol-Rich Essential Oils: In Vitro Study on the Phytopathogenic Fungi Alternaria and Fusarium
www.mdpi.com/2673-9976/54...

By Vasileios Papantzikos et al.
From the IOCAG 2025 Conference

#Antifungal #PlantPathology

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Evaluation of the Antifungal Effect of Carvacrol-Rich Essential Oils: In Vitro Study on the Phytopathogenic Fungi Alternaria and Fusarium

#AntifungalEffect
#Fungi
#Alternaria
#Fusarium
#antifungal
#carvacrol
#postharvestdiseases

www.mdpi.com/2673-9976/54...

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#SIF
🔬Trichoderma metabolites show strong antifungal activity against postharvest pathogens! Promising biocontrol solution!
Details: maxapress.com/article/doi/10.48130/sif...
#Biocontrol #Postharvest #Antifungal #Trichoderma

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How Antifungal Medicines Work in Managing Fungal Diseases? Antifungal drugs fight infections caused by fungi. These infections show up in all sorts of ways sometimes as a mild rash, sometimes as something much more serious, affecting your lungs, blood oreven your organs. The drug you need depends on the kind of fungus and where it’s causing trouble. Some antifungals punch holes in the fungus’s cell membrane; others mess with how it grows or reproduces.Azoles are one of the main types of antifungal drugs. You’ve probably heard of names like fluconazole,

#Azoles are one of the main types of #antifungal drugs. You’ve probably heard of names like #fluconazole, #itraconazole #Zisavel 100mg Capsule, #ketoconazole #orvoriconazole. They work by stopping #fungi from making #ergosterol.

mrmedpharmacy.wixsite.com/blog/post/ho...

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A New Fungal Fighter A modified macrolide called mandimycin, uniquely targets fungal cell membranes, offering potent activity against multidrug-resistant fungal pathogens.

A New Fungal Fighter

A novel antifungal discovery could tip the scales in our fight against drug resistance! 🧫⚔️ Meet the next-generation compounds targeting tough fungal infections.

🔗 buff.ly/QbxXf6K

#WAAW2025 #Antifungal #AMR

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#Gquadruplexes can form within fungal pathogens and represent new #antifungal targets ➡️ doi.org/10.1038/s443...

By G. Middleton, F. Mahamud, I. Storer, Z. Waller, S. Bidula & colleagues at @ucl.ac.uk & @uniofeastanglia.bsky.social

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Multifunctional nitrogen and boron co-doped carbon dots: A fluorescent probe for Hg2+ and biothiol detection with bioimaging and antifungal applications

Multifunctional nitrogen and boron co-doped carbon dots: A fluorescent probe for Hg2+ and biothiol detection with bioimaging and antifungal applications

This Open Chemistry article demonstrates the synthesis of nitrogen & boron co-doped #CarbonDots, which enable the detection of mercury & #Biothiols, with potent applications in #Bioimaging and as #Antifungal agents.

#OpenAccess: doi.org/10.1515/chem...

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🦠 Meet the Speaker

👩‍🔬 Prof. Chowdhary is a leading expert in medical #mycology, researching #antifungal resistance and emerging fungal pathogens like Candida auris and Aspergillus fumigatus.
She is Secretary General of ISAC
tinyurl.com/3554edz2
📅 3 Nov 2025 | 11:00–12:30 CET
@souhakanj.bsky.social

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👑 The crown jewel of antifungal research has everyone talking. At the #museum of #biochemistry, all eyes are on the crown jewel of antifungal research: #Fluconazole (HY-B0101). A powerful #antifungal featured in 17 research publications.
🔗 www.medchemexpress.com/Fluconazole....

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Redirecting

Researchers at @pmresearch-uhn.bsky.social have discovered how a molecule called palmitoyl-CoA acts as an “off switch” for a key fungal enzyme that makes fatty acids.

This finding could inform the development of more effective #antifungal therapies.

🔗Read the full study: doi.org/10.1016/j.st...

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#GAMRIC2025 day 2 session in defining the challenges in #antifungal drug R&D: case numbers low but clinical need for better treatments is urgent! Thru PK/PD data combined w/ adapted study designs can accelerate journey to access.
#IDSky

@carb-x.bsky.social @lifearc.bsky.social @gardp.bsky.social

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Best Antifungal Medications | Antifungal Medications - Oddwayinternational

More Info - themediumblog.com/blog/best-an...

#Antifungal, #AntifungalMedication, #WholesaleMedicine, #OnlineMedicine, #GenericDrugs, #fungalinfection, #fungal, #skincare, #skininfection, #fungalnailtreatment

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In situ #ZnO, SiO2, and #TiO2 particle formation in #ScotsPine & Norway spruce wood enhances surface hydrophobicity and #UVResistance & strengthens #antifungal protection, enabling #ecofriendly #HybridWood development.

#OpenAccess in Nanotechnology Reviews: doi.org/10.1515/ntre...

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Best Antifungal Medications: A Guide to Effective OTC Antifungal Treatments
www.edocr.com/v/w7le02nq/o...

#Antifungal #AntifungalMedication #WholesaleMedicine #OnlineMedicine #GenericDrugs #fungalinfection #fungal #skincare #skininfection

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Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies This review highlights the integration of drug repurposing and nanotechnology-driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidi...

Now available in Open Access:
Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology-Driven Delivery Strategies

#pharmacology #SFPT #Wiley #clinical #fundamental #statin #antifungal #drug #candidiasis #nanotechnology #treatment

onlinelibrary.wiley.com/doi/10.1111/...

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