Our case study showcase #bioinformatic analyses we performed for NeoPhore, in relation to their proprietary small molecule PMS2 MMR protein inhibitor!

See what we found out! 👀
www.fiosgenomics.com/pharmacological-inhibiti...

#drugdevelopment

Virtual workshop on #genomics analysis for #RADSeq - spaces available Jan 13-16th! Live instruction by @noahreid.bsky.social Learn #NGS read QC, #variant detection, and data analysis via common #bioinformatic tools - #Stacks #Freebayes @uconnresearch.bsky.social @cbcuconn.bsky.social

This paper evaluates how multiple #largelanguagemodels generate end-to-end #bioinformatic pipelines for a metaviral workflow.

Tissue Kallikrein as a Mediator in Stroke Outcomes among Patients With Metabolic Syndrome: A Multicenter Study Integrating Big Data and Biomarkers Metabolic syndrome is associated with adverse stroke outcomes. KLK1 acts as a mediating factor linking metabolic syndrome and stroke prognosis. KLK1 could be a therapeutic target for stroke patients ...

#Article in #MedComm
Tissue Kallikrein as a Mediator in Stroke Outcomes among Patients With Metabolic Syndrome: A Multicenter Study Integrating Big Data and Biomarkers doi.org/10.1002/mco2...

#BigData #bioinformatic #KLK1 #MachineLearning #MetabolicSyndrome #stroke

Virtual workshop on #genomics analysis for #RadSeq - spaces available still for next week - Dec 16-18th! Live instruction by @noahreid.bsky.social Learn QC through data analysis using common #bioinformatic tools - #Stacks #Freebayes @uconnresearch.bsky.social @cbcuconn.bsky.social

Job offer: PostDoc in biotic and trophic interactions 90% (f/m/d) As part of the interdisciplinary PAPPUS project, which explores how plant communities and urban green space management support biodiversity and residents' quality of life, you will work with existing data. Your focus will be on analyzing biotic and trophic interactions between plants and arthropods, including predators, herbivores, pollinators, and detritivores. The data were collected from 60 public and private green spaces in Zurich. Your first task will be to analyse metabarcoding data from over 1200 invertebrate samples to generate a species lists. You will then examine the structure of mutualistic and antagonistic multitrophic networks, including food webs, and model their responses to urbanisation, management intensity, and plant preferences among residents. The position offers flexibility to develop your own research ideas within the scope of PAPPUS. You are expected to publish your findings in high-impact journals and present them at international conferences. Engagement with practitioners, especially through presentations and outreach in French, is also an important part of this PostDoc. You have a PhD degree in environmental science or in a related field. You have a good publication record as well as a background in ecological sciences and quantitative analyses. Proficiency in bioinformatic, metabarcoding, multitrophic ecology (food web), and ecological modelling is required, as is good knowledge of trait-based ecology. Practical and interdisciplinary experiences (e.g., with urban engineers) and knowledge of the principles and theories of urban ecology are helpful. You are ambitious, motivated and communicative. You are used to a high standard of independent, structured and you demonstrate a high level of team spirit. Proficiency in English and French, as well as good knowledge in German is required.

🌿 #PostDoc Alert! PhD in #EnvironmentalSciences? Proficient in #bioinformatic, #EcologicalModelling and good knowledge of trait-based #ecology🦋? Our #ConservationBiology group offers a PostDoc position in biotic and trophic interactions🐜: apply.refline.ch/273855/1769/... #UrbanEcology #ScienceJobs

Use your chance to join the #TERRA team @unituebingen.bsky.social: 7-year position waiting for sbd. to advance #bioinformatic analysis in the context of bio-geo-diversity relations. Tübingen itself is a convincing reason, but our amazing #cluster team even more. We look forward to your application!

Frontiers | CATS: a bioinformatic tool for automated Cas9 nucleases activity comparison in clinically relevant contexts IntroductionWith the growing number of Cas9 nucleases available to genetic engineers, selecting the most suitable one for a given application can be challeng...

Say hello to CATS, our new #bioinformatic tool that automates the comparison of #Cas9 nucleases and identification of #allele-specific #targets for mutations, making #CRISPR-Cas9 design faster and more precise!
GitHub: github.com/Physics4Medi...
Paper: www.frontiersin.org/journals/gen...

Tools and resources We develop a range of software and bioinformatic tools to support the life sciences across data management and analysis.

💻 Our scientists develop software and #bioinformatic tools to support the #lifesciences across data management and analysis, including:

🌱 Sharing of field trial #data
💾 #Metadata management
🧬 Amplicon sequencing analysis

What sorts of #bioinformatic tasks, tools, or processes do you wish were more user friendly or accessible to non-bioinformaticians? I'm looking to potentially build some tools (especially for the #fungal community) that can help biologists get the most out of their data and speed up their science!

AlphaGenome: AI for better understanding the genome Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API.

Google Deepmind: "AlphaGenome: #AI for better understanding the #genome"

#bioinformatic #science

deepmind.google/discover/blo...

💼 Meet the Finance Committee of #SCS2025!
They’re the team making sure everything adds up behind the scenes 💰

🙌 Huge thanks Estefanía, Muhammed & Souman Dey!

📍 Liverpool, 20 July 2025
#ISCB #CompBio #Bioinformatic

🎨 Meet the creative minds behind #SCS2025!
Our amazing Design Committee is bringing the 21st ISCB Student Council Symposium to life 💫

🙌 Huge thanks to Ece, Gizem, Divy, Vuslat, Isabella & Akifur!

📍 Liverpool, 20 July 2025
#ISCB #CompBio #Bioinformatic

Do you have an interesting benchmark experiment?

We wanna hear about it!

Special issue in Genome Biology live now: www.biomedcentral.com/collections/...

Submission Deadline: 28 January 2026

#bioinformatic #genetic #genomics
please share with your peers!

SeroBA(v2.0) and SeroBAnk: a robust genome-based serotyping scheme and comprehensive atlas of capsular diversity in Streptococcus pneumoniae The unprecedented number of Streptococcus pneumoniae (the pneumococcus) genomes sequenced in recent years has accelerated the discovery of novel serotypes and highlighted the genetic diversity both be...

Do you need a #bioinformatic tool to detect almost all serotypes in #pneumococci?

The new SeroBA v2.0 can detect 102 of 107 known pneumococcal serotypes

www.biorxiv.org/content/10.1...

Issues · GlobalPneumoSeq/seroba A Fork of the Original SeroBA. Contribute to GlobalPneumoSeq/seroba development by creating an account on GitHub.

Do you need a #bioinformatic tool to detect almost all serotypes in #penumococci ?

The new SeroBA v2.0 can detect 102 of 107 pneumococcal serotypes

github.com/GlobalPneumo...

An integrated multitool analysis contributes elements to interpreting unclassified factor IX missense variants associated with hemophilia B Dissection of genotype–phenotype relationships in hemophilia B (HB) is particularly relevant for challenging (mild HB) or for HB-associated but unclassified factor (F)IX missense variants.

Researchers in Italy and China used a multitool #bioinformatic approach to identify new F9 gene mutations that cause #HemophiliaB and explored their effects on disease severity.
www.jthjournal.org/article/S153...

See also: www.jthjournal.org/article/S153...

INSR variant classification with up-to-date #bioinformatic tools highlights the strengths and weaknesses of routine #molecular #diagnosis bit.ly/4i9CLi0

Knot so simple: untangling bacterial chromosome structure, conformation and gene expression (EVANS_U25MMB) at University of East Anglia on FindAPhD.com PhD Project - Knot so simple: untangling bacterial chromosome structure, conformation and gene expression (EVANS_U25MMB) at University of East Anglia, listed on FindAPhD.com

Our @emmabeansworth.bsky.social & @gemma-langridge.bsky.social are part of this awesome #PhD opportunity with @benaevans.bsky.social. If you are at #Microbio25, interested in or know someone interested in doing a #PhD with some amazing #bioinformatic training alongside go talk to Gemma

Please share

Host-pathogen environmental genetic surveillance: pathogen emergence and crop protection

Applications are open for this #PhD, developing #bioinformatic skills for pathogen diversity analysis. You'll be working on #crop #pathogen surveillance and analysis methodologies to identify pathogen reservoirs and predict emergence.

📆 Start date: 01 Oct
📍 Open to UK students

Here is an awesome #PhD opportunity, with some pretty sweet #bioinformatic training & a great supervisory team. Wanna understand how bacterial chromosomes change with antibiotics? This is the PhD for you!
@mmbdtp.bsky.social

Long-reads Bioinformatics Summer School A bioinformatics summer school on analysis of long-reads technology data, hosted by the Long-reads TRanscriptome European Consortium (LongTREC).

Join the @longtrec.bsky.social network for a #longreads #bioinformatic summer school workshop at the Earlham Institute. 🖥️ 🧬

A 4-day course introducing diverse topics in #longread science.
buff.ly/UQAjcB7

@anaconesa.bsky.social @whaerty.bsky.social

Bienvenue l' @ifb-elixir-fr.bsky.social sur le #BioStream4 !

Juliette, Morgane, Gildas, Lucie et Imane nous présentent les missions et les différents projets de l'IFB 🚀🧬

#Bioinformatique #bioinfo #bioinformatic #BioStream

Préparez le popcorn et vos questions pour le #BioStream de ce soir avec @ifb-elixir-fr.bsky.social !📽️🧬🍿

➡️ www.youtube.com/@RSGFranceJe...
➡️ www.twitch.tv/jebif_rsg_fr...

#bioinfo #bioinformatique #bioinformatic #live #stream #science #IFB #JeBiF

🎉See C versions of Arima Genomics mapping pipeline tools (htslib library). These tools are designed to efficiently process & analyze HTS sequencing data, particularly for Hi-C & other chromosome conformation capture experiments.
github.com/Genoscope-LBGB/arima_htslib

#bioinformatic #genomic #Hi-C

I'll be attending #AGBT25 to learn about new genomic technologies and their #bioinformatic needs. If you have a #bioinformatic need, or want to learn more about what @fulcrumgenomics.com can solve, please reach out to myself or @tfenne.bsky.social.

📢 An exciting #Postdoc position opened in our laboratory for a junior #Bioinformatician!

Developing #Bioinformatic and #AI tools to advance precision oncology using the available #singlecell / #spatial data universe.

careers.adelaide.edu.au/cw/en/job/51...

Pls share! 🙏

#postdocposition

A friend asked for resources to learn R as biologist
2 years ago I bought courses, most were repetitive “Hello World”
I tried FigOneLab by Dean Lee #NoAd before recommending it
Liked that it’s direct application to actual #bioinformatic use
Any other recommendations for beginners? #academia #biology

FishPi software logo

🚨Our new paper @immler.bsky.social @biouea.bsky.social 🚨
FishPi: a #bioinformatic prediction tool to link #piRNA and #transposable elements
Read now in Mobile DNA >> rdcu.be/d7Jub
✅ Covers many species (more to come)
✅ GUI based software
#TESky #zebrafish #transposons
@zebrafishrock.bsky.social

The last talk of the #gene #regulation and #disease is by Jacques van Helden from @univ-amu.fr, who has been a teacher at LCG-UNAM since its birth 20 years ago! He is telling us about #bioinformatic approaches to decipher cis-regulatory elements @liigh-unam.bsky.social #LIIGH10anniversary