Energy stress activates AMPK to arrest #mitochondria via phosphorylation of TRAK1. New study from Jill E. Falk, Thomas L. Schwarz and colleagues @bostonchildrens.bsky.social: rupress.org/jcb/article/...
#Metabolism #Neuroscience #Organelles #CellMetabolism #Cytoskeleton
Mechanometabolism of cell adhesion: #Vinculin regulates #bioenergetics via RhoA-ROCK. New study from Emily D. Fabiano, Cynthia A. Reinhart-King (Rice University) and colleagues: rupress.org/jcb/article/...
#Biophysics #Cancer #CellMetabolism #Migration #motility #Actin #Cytoskeleton
Potassium ion homeostasis modulates mitochondrial function, say Adam James Waite, Daniel E. Gottschling and colleagues (Calico Life Sciences): rupress.org/jcb/article/...
#CellMetabolism #Metabolism #Genetics #Organelles #Mitochondria #Aging
#EPI
DNA replication coordinates with cell metabolism, fundamental for growth. Recent advances show metabolic cues directly impact replication fork stability and function!🧬⚡
Details: www.maxapress.com/article/doi/10.48130/epi...
#epigenetics #dnareplication #cellmetabolism #stability
¿Por qué la grasa pegada al colon ‘habla’ con tus defensas? #grasaabdominal #saludintestinal #inflamacion #microbiota #ciencia #investigacion #medicina #salud #CellMetabolism #InstitutoKarolinska #enfermedadinflamatoria #colon #obesidad #16deenero #felizviernes donporque.com/la-grasa-peg...
Mitochondrial presequences harbor variable strengths to maintain organellar function. New study from Youmian Yan, Natalie Niemi (@nieminm.bsky.social) et al. @washumedicine.bsky.social: rupress.org/jcb/article/...
@ianofbristol.bsky.social
#Biochemistry #CellMetabolism #Organelles #Mitochondria
New #CellMetabolism paper: Gut microbiome-adipose crosstalk modulates soluble IL-6 receptor influencing exercise responsiveness in glycemic control and insulin sensitivity. #Myoblue tinyurl.com/3b8dtpzd
Irg1l regulates neuromast size via metabolic reprogramming to promote supporting cell proliferation. New study from Xin Wang, Ruijun Shi, Yuqing Xiang, Yajing Gao, Guoqiang Wan, Shan Sun, and Dong Liu (Nantong University): rupress.org/jcb/article/...
#CellMetabolism #Development #Zebrafish
In @jcb.org, Xin Wang et al. identify Irg1l as a regulator of #zebrafish neuromast size. They demonstrate that the Irg1l/itaconate axis promotes supporting cell proliferation by inducing metabolic reprogramming that activates Yap signaling rupress.org/jcb/article/...
#CellMetabolism #Development
Xin Wang et al. identify Irg1l as a regulator of #zebrafish neuromast size. They demonstrate that the Irg1l/itaconate axis promotes supporting cell proliferation by inducing metabolic reprogramming that activates Yap signaling rupress.org/jcb/article/...
#CellMetabolism #Development
Lipid droplets: Open questions and conceptual advances around a unique organelle. New review from Mike Henne (@hennelab.bsky.social), Emma Reynolds, and William: rupress.org/jcb/article/...
#Biochemistry #CellMetabolism #LipidDroplets
New review: Henne (@hennelab.bsky.social), Reynolds, and Prinz discuss recent discoveries and enduring mysteries in the lipid droplet field. rupress.org/jcb/article/...
#Biochemistry #CellMetabolism #LipidDroplets
New review @jcb.org: Henne (@hennelab.bsky.social), Reynolds, and Prinz discuss recent discoveries and enduring mysteries in the lipid droplet field. rupress.org/jcb/article/...
#Biochemistry #CellMetabolism #LipidDroplets
Mechanisms of genome instability from cellular folate stress. New review from Christopher Mellor, Elisabeth Larson, and Meng Wang @drmengwang.bsky.social @cornelluniversity.bsky.social: rupress.org/jcb/article/...
#CellMetabolism
New review @jcb.org: Mellor, Larson, and @drmengwang.bsky.social discuss the molecular mechanisms of mammalian genomic instability arising from folate deficiency and how this impacts genome biology in health and disease. rupress.org/jcb/article/...
#CellMetabolism
New review: Mellor, Larson, and @drmengwang.bsky.social discuss the molecular mechanisms of mammalian genomic instability arising from folate deficiency and how this impacts genome biology in health and disease. rupress.org/jcb/article/...
#CellMetabolism
New insights into the lipid droplet breakdown in alcohol-associated hepatic #steatosis. Chen Zhang and Wen-Xing Ding @kumedcenter.bsky.social highlight new work from Sen et al. (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...
#CellMetabolism #Disease #LipidDroplets
Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity
👉 buff.ly/IoEPOTs
🥼 @OscarLlorcaCNIO @CNIOStopCancer
#mTORC1 #CellMetabolism #Chaperones
Acidosis attenuates the hypoxic stabilization of HIF-1α by activating lysosomal degradation, say Bobby White, Pawel Swietach and colleagues @oxforddpag.bsky.social @ox.ac.uk: rupress.org/jcb/article/...
#Biochemistry #CellSignaling #Cancer #CellMetabolism #Hypoxia
ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the #FanconiAnemia pathway. From Moonjung Jung, Jungwoo Kim, Agata Smogorzewska @rockefelleruniv.bsky.social and colleagues: rupress.org/jcb/article/...
#CellMetabolism #DNAbiology #Disease #Genetics #DNADamage
How do omega-3s fight #inflammation?
🧪 In monocytes, ALA and DHA shift energy #metabolism and suppress #inflammatory cytokines. DHA may act through PDK4—a key regulator of glucose oxidation.
doi.org/10.1139/bcb-...
#Immunology #n3PUFAs #Type2Diabetes #CellMetabolism
Bobby White, Pawel Swietach et al. @oxforddpag.bsky.social show that sustained hypoxic stabilization of HIF1a requires alkaline conditions, which may not be representative of most under-perfused tumors. rupress.org/jcb/article/...
#Biochemistry #CellSignaling #Cancer #CellMetabolism #Hypoxia
In @jcb.org, Bobby White, Pawel Swietach et al. @oxforddpag.bsky.social show that sustained hypoxic stabilization of HIF1a requires alkaline conditions, which may not be representative of most under-perfused tumors. rupress.org/jcb/article/...
#CellSignaling #Cancer #CellMetabolism #Hypoxia
The reaction mechanism for #glycolysis side product degradation by #Parkinsons disease–linked DJ-1. New study from Aiko Watanabe, Yoshitaka Moriwaki, Noriyuki Matsuda and colleagues (Institute of Science Tokyo): rupress.org/jcb/article/...
#Disease #CellMetabolism
In @jcb.org, Watanabe, Moriwaki, Matsuda et al combine in silico molecular modeling with cell-free experimental analyses of DJ-1 mutants & present an evidence-based mechanism for DJ-1–mediated cPGA hydrolysis & its significance in #Parkinsons disease rupress.org/jcb/article/...
#CellMetabolism
Watanabe, Moriwaki, Matsuda et al combine in silico molecular modeling with cell-free experimental analyses of DJ-1 mutants & present an evidence-based mechanism for DJ-1–mediated cPGA hydrolysis & its significance in #Parkinsons disease rupress.org/jcb/article/...
#CellMetabolism
In addition to #OxygenConsumption and concentration, Resipher continuously streams incubator temperature, relative humidity, atmospheric pressure, and other environmental factors.
Learn more & request a free trial >>> bit.ly/44vPHJS
#Mitochondrial #CellMetabolism
Our CEO Walker Inman, PhD providing a brief overview of how the #Resipher works and how it can accelerate your research.
#oxygenconsumption #cellmetabolism #cellculture #scientificresearch
🧬 Your REAL age isn’t on your ID. It’s in your cells.
Turns out, how old you feel might be more real than how old you actually are. Science is ditching ”actual age“ and looking at biological age instead. 🧠🔬
#biologicalage
#cellmetabolism
#slowaging
#cortisolcontrol
🔬 Th1nk Tank Alert! 🔬
How does mitochondrial signaling shape metabolic tissue identity? 🧬
🗓 Apr 17, 2025 | 12 PM ET
🔗 Register: us02web.zoom.us/meeting/regi...
#DiabetesResearch #T1D #Mitochondria #BetaCells #IsletBiology #CellMetabolism #BiomedicalScience
