In a new study in Science Translational Medicine, utilizes epigenomic mapping with EpiCypher's CUTANA™ CUT&RUN revealing a new combo therapy for aggressive pediatric brain tumors.
🔗Read more: www.science.org/doi/10.1126/scitranslmed...
#Epigenetics #ChromatinBiology #CancerTherapeutics

As I linked to before, these manuscripts can be found @biorxivpreprint.bsky.social. And just so we get the right audience… #medsky #sciencesky #cryoEM #proteimics #systemsbiology #crosslinking #structuralbiology #epigenetics #transcription #chromatinbiology #proteomicsky #massspecsky

An Epigenetic Perspective of Gene Expression: The Regulatory Tools

dl.begellhouse.com/journals/6db...

#EpigeneticsResearch #GeneRegulation #ChromatinBiology #CRE

Chromatin remodeling at the C-REPEAT BINDING FACTOR cluster controls growth retardation at low ambient temperature Plants adapt to low ambient temperatures using a temperature-sensitive control system that remodels chromatin to control growth.

🌱 How do plants use dynamic chromatin remodeling to fine-tune transcriptional responses to cold?
Polycomb VIL1 uses H3K27me3 to regulate chromatin architecture at the CBF cluster, modulating growth at low ambient temperature.
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🔗 doi.org/10.1093/plce...

#PlantScience #Epigenetics #ChromatinBiology

Cohesin mutations and chromatin changes in cancer - PubMed The identification of recurrent mutations in genes encoding the cohesin complex in cancer was among the most unexpected findings from cancer exome sequencing studies. Cohesin is a multi-subunit protein complex that is essential for sister chromatid cohesion, three-dimensional chromosome organization …

🧬The Ring of Life

The cohesin ring gently folds our DNA, keeping the quiet rhythm of our genes in order. When this ring breaks, the loops unravel, but science is finding a way to mend the story.

🔗 pubmed.ncbi.nlm.nih.gov/40063003/

#MolecularBiology, #DNARepair, #ChromatinBiology,

Join our virtual seminar!

@sedonamurphy.bsky.social presents cutting-edge research on 3D genome organisation & epigenetic memory in development, moderated by @stefanschoenfelder.bsky.social

📅 Jan 8, 4pm UK
💻 Zoom

Register: us02web.zoom.us/webinar/regi...

#3DGenome #Epigenetics #ChromatinBiology

Happy New Year from all of us at EpiCypher! 🧬

Here’s to fresh experiments, better data, and bold chromatin discoveries in 2026. We’re excited to keep advancing epigenetics together.

#Epigenetics #ChromatinBiology #LabLife

A #PKUResearch paper published in Nucleic Acids Research reveals how PICKLE (PKL) promotes H3K4me2 modification and orchestrates spatial gene clustering in Arabidopsis chromatin.

doi.org/10.1093/nar/...

#PekingUniversity #ChromatinBiology #Epigenetics #PlantScience @narjournal.bsky.social

Summary - Summer School on Chromatin Biology: A Hands-On Expedition

👉 Chromatin Summer School 2026 – Apply Now!
Join us in Munich 17–29 August 2026 for an immersive program on chromatin biology:
🔬 Expert lectures
🧪 Hands-on training
🤝 Global networking
Open to 14 PhD students worldwide (sponsorship available)
👉 Apply here: bit.ly/4oGDR8f
#ChromatinBiology

Dynamic #DNA control: HMGA proteins interact with nucleosomes to fine-tune chromatin structure and #gene expression — a key mechanism in differentiation, development, and cellular aging. #ChromatinBiology #MolecularBiology
https://ow.ly/Mz5z50Xx4eL

Kicked off #SfN2025 strong yesterday.
Great talks, great people, and even better science. We’re here for Day 2 and excited to keep the momentum going.

Swing by the booth and let’s talk epigenetics 🧬

#Epigenetics #ChromatinBiology

🙌 Developed with Philipp Lorenz & Anna Lamstaes, continued under Jane Mellor’s guidance.
💬 Submitted for peer review – feedback welcome!
#SNUSeq #4sUSeq #chromatinbiology #OpenScience

[New #Blog] What if targeting CBP/p300 could unlock a new therapy for SMARCB1-deficient tumors? 🧬

Discover the latest epigenetic insight in Active Motif's new blog 👉 bit.ly/4gkO1J1

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#Blog #ActiveMotif #Epigenetics #ChromatinBiology #CancerResearch #CBP #OncologyResearch #GeneRegulation

Did anyone notice today’s Google Doodle? 👀🧬

It highlights DNA — life’s blueprint. At Active Motif, we take it a step further by helping researchers explore epigenetics: how DNA is packaged, regulated, and expressed.

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#GoogleDoodle #Epigenetics #ChromatinBiology #ActiveMotif

Synapse: Your Connection to our MSK Authors
Meet: Juan Yan
Research Focus: Human Oncology and Pathogenesis Program; Senior Research Scientist

synapse.mskcc.org/synapse/work...

#KMT2C #KMT2D #KMT2A #Epigenetics #UrothelialCancer #BladderCancer #Tumorigenesis #ChromatinBiology #GeneRegulation

🧬 Heading to #GenomeScience25 in Newcastle!

Catch up with
‪@milescollier.bsky.social‬, our EMEA Sales Director, at Stand #2 — he's looking forward to great chats on genome architecture, epigenetics & more. See you there!

#Genomics #Epigenetics #ChromatinBiology

Excited to see our review on the 3D genome in the cell cycle, DNA repair and DNA replication out today!
#3Dgenome #replication #DNArepair #cellcycle #epigenetics #chromatinstructure #chromatinbiology

www.frontiersin.org/journals/cel...

Explore chromatin remodeling in disease & development- From PRC2-mediated regulation to pioneer factors & phase separation. New technologies reveal dynamic chromatin-gene expression interplay.

Learn clinical applications: dataprudence.com

#Epigenetics #ChromatinBiology