Short bursts of exercise can lower disease risk Curated by <b>Smartbrief</b>. Short bursts of intense physical activity can significantly reduce the risk of serious diseases, including heart disease, type 2 diabetes and dementia, according to a stu...

Mayor proporción de actividad física vigorosa se asocia inversamente c/enf crónicas y mortalidad por todas las causas, intensidad muestra un potencial preventivo mayor que el volumen, hay que priorizar actividades de alta intensidad #physicalactivity #cvd newsletter.smartbrief.com/sharedSummar...

Prediabetes and 20-year cardiovascular disease incidence: the ATTICA cohort study (2002–2022) AbstractAims. Individuals with prediabetes carry an increased cardiometabolic burden; however, the extent to which prediabetes contributes to cardiovascula

Prediabetes definida por la alteración de la glucemia en ayunas es un predictor independiente de enfermedad CV, y el inicio más temprano de la diabetes tipo 2 aumenta el riesgo de enfermedad CV #IFG #CVD #T2D academic.oup.com/eurjpc/artic...

Evolocumab for Reducing MACE, Lead Exposure and CVD, AI Scribes for Clinicians, and more Editor’s Summary by Linda Brubaker, MD, Preeti Malani, MD, MSJ, Deputy Editors of JAMA, and Gregory Curfman, MD, Executive Editor of the Journal of the American Medical Association, for articles published from March 28-April 3, 2026.

JAMA Deputy Editors Linda Brubaker, MD, and Preeti Malani, MD, MSJ, and Executive Editor Gregory Curfman, MD, discuss the latest science published in JAMA:

➡️ #Evolocumab for Reducing MACE,
➡️ #Lead Exposure and #CVD, and more.

ja.ma/41JePfE

An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice - npj Metabolic Health and Disease npj Metabolic Health and Disease - An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice

How do genetic variants of #interleukin-6 (#IL6) contribute to #cardiometabolic disease? With help from Promethion #Metabolic Cages, scientists tested a knock-in mouse model of the IL6 promoter variant #rs1800795. 🧪

buff.ly/GDBusEN

#Respirometry #Metabolism #CVD #HFD

Modern EBRT reduces CVD risk in breast cancer patients Modern EBRT for breast cancer treatment leads to minimal increases in CVD risk, an improvement over previous EBRT techniques.

Advances in external beam radiation therapy (EBRT) techniques in breast cancer treatment have mitigated cardiovascular disease (CVD) risk in women #radiology #breastcancer #EBRT #CVD

An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice Chronic elevations in interleukin-6 (IL6) signaling have been shown to exacerbate features of cardiometabolic disease. A common variant in the IL6 promoter (location -174 G/C, identifier rs1800795) is...

How do genetic variants of #interleukin-6 (#IL6) contribute to #cardiometabolic disease? With help from Sable Promethion #Metabolic Cages, scientists tested a knock-in mouse model of the IL6 promoter variant #rs1800795.

buff.ly/GDBusEN

#Respirometry #Metabolism #Inflammation #Adipose #CVD #HFD

Both adherence to a #healthy #lifestyle and #GLP-1 receptor agonist use are independently associated with low risk of #MACE among veterans with type 2 #diabetes, and their combination is associated with a greater risk reduction than either approach alone
www.thelancet.com/journals/lan...
#T2D #CVD

The Disappearing Benefits of GLP-1 Drugs The weight-loss and heart benefits of GLP-1 RA drugs like Ozempic build over time. They also fade if the medication is stopped.

The Disappearing Benefits of GLP-1 Drugs
The weight-loss and heart benefits of GLP-1 RA drugs like Ozempic build over time. They also fade if the medication is stopped. www.thedoctorwillseeyounow.com/content/hear... @bmjmedicine.bsky.social #cardio #zepbound #tirzepatide #semaglutide #cvd #GLP

While waiting for FOCUS, analysis of a matched real world TriNetX cohort of 350,536 patients with #T2D and #CVD followed for up to 5 years revealed reduced rates of legal blindness pubmed.ncbi.nlm.nih.gov/41907810/

Cardiovascular Disease in Singleton Offspring Born of Pregnancies Complicated by Placental Abruption: A Population‐Based Retrospective Cohort Study | Journal of the American Heart Association

Descendientes nacidos de embarazos complicados por placenta abrupta sufren mayor mortalidad y enf CV, evidente durante la infancia y persistiendo a lo largo de la vida, lo que subraya la disfunción placentaria microvascular #abruption #placenta #cvd www.ahajournals.org/doi/10.1161/...

Beyond the heart: the urgent need for a dementia-forward diabetes agenda The clinical practice of diabetes management has undergone a paradigm shift over the past two decades. GLP-1 receptor agonists and SGLT2 inhibitors have expanded the therapeutic focus beyond glycaemic...

Linked Comment:
Beyond the #heart: the urgent need for a #dementia-forward #diabetes agenda www.thelancet.com/journals/lan...
#T2D #CVD

#MedSky #EndoSky

Mortality from #cardiovascular disease and #diabetes has declined among people with diabetes in most jurisdictions, whereas mortality from #dementia has increased markedly, independent of age www.thelancet.com/journals/lan...
#T2D #CVD

#MedSky #EndoSky

We can’t wait to dive into day 2 of #ACC26! Join DCRI faculty as they tackle cardiogenic shock, #HeartFailure, GLP-1s, #CKD & #CVD prevention, health misinformation, and AI-powered arrhythmia care. dcri.org/acc #CardioSky

11/ Conclusions 2: #EBPM pyrolysis route demonstrates greater energy efficiency and economic viability compared to the #CVD route, through 2030 to 2050.

9/ Sensitivity analysis shows a negative correlation between investment cost reduction and the minimum GR selling price needed for break even. Production costs show only limited sensitivity to cost of capital changes of ±2% for both #CVD & #EBPM pyrolysis routes.

8/ By 2050, energy contributes only 1.42% of total #CVD GR cost, compared to 55.8% for #EBPM GR. With a #CVD GR sales price of 98.4 €/kg, e GR becomes profitable by 2050. #EBPM GR is also profitable in 2050 with a sales price of 9.2 €/kg.

7/ Excluding energy, #CVD GR costs fall from 26,295 to 24,057 €/tCO2, (96.4 to 88.2 €/kgGR) between 2030-2050, due to electrolysis, direct air capture, and e-methane. #EBPM pyrolysis GR is far economical, dropping from 394 to 163 €/tCO2 (1.45 to 0.60 €/kgGR) over same period.

6/ Energy & mass balances show 3.67 tCO2 stored per tGR. CO2 removal could reach 2.57 GtCO2/a by 2050. By 2050, total electricity demand is 21.9 MWhel/tCO2 (80.3 MWhel/tGR) for #CVD and 13.1 MWhel/tCO2 (47.9 MWhel/tGR) for #EBPM pyrolysis.

4/ Production of single-layer GR via #CVD route with methane as the carbon feedstock can be entirely based on renewable electricity, water, and CO2 from the atmosphere, named as e-GR. Utilising a copper recycling scenario further reduces primary energy consumption.

3/ High energy intensity and fossil methane usage as the carbon feedstock makes conventional production of GR through chemical vapor deposition #CVD & electron beam plasma methane #EBPM pyrolysis, highly unsustainable.

Just your reminder - If Tony Hawks Underground from 2003, a 23 year old game, can support entirely full HSV values, and the entire spectrum to color change a character. You can do it for #CVD (colorblind) support in #gamedev. No more 'swatches and filters', stencil buffer to HSV please. <3

Gene Editing Therapy in Cardiovascular Disease: 2026 ACC Scientific Statement: A Report of the American College of Cardiology Download article citation: If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

New 2026 ACC scientific statement reviews gene editing therapy in #CVD, covering the science, early targets (monogenic diseases), and key ethical and cost challenges. Clinicians play a critical role in guiding safe, equitable use. https://bit.ly/4rYSW6W

#JACC #CRISPR #cvGenetics #CardioSky

ICYMI - UBC TI #BestEvidence Webinar recording!

"GLP-1 RA and SGLT2i in type 2 diabetes"
Speaker: The TI's @guillaume-grenet.bsky.social

👉 View recording: youtu.be/JUCIfScMqGY

#MedEd #CME #diabetes #CVD

Today is #LpaAwarenessDay. Elevated lipoprotein(a) is genetic, affects 1 in 5 people, and increases risk of CVD & stroke. Most don’t know their levels – testing can help identify those at risk.

Learn more: https://ow.ly/ba7s50Yrl0h

#Lp(a)Awareness #Stroke #CVD #HeartHealth

People with #MASLD can progress to cirrhosis and hepatocellular carcinoma and are at increased risk of developing type 2 #diabetes, #cardiovascular disease, chronic #kidney disease, and extrahepatic cancers www.thelancet.com/journals/lan...
#T2D #CVD #CKD
#OpenAccess

#MedSky #EndoSky #LiverSky

♡ Life's Essential 8™ - The Key Markers of Heart Health in a Single Image:

Reference: doi.org/10.1161/CIR....

2026 JACC guidelines: www.jacc.org/doi/epdf/10....

Order a Lipids panel anytime: rxhometest.com/product/chol... #heart #cvd #hearthealth ❤️

Revisiting the burden and patterns of myocardial infarction in type 1 diabetes Type 1 diabetes confers a cardiovascular burden that is often obscured by the young age of affected individuals and by the longstanding focus on microvascular rather than macrovascular complications. ...

Angelo Avogaro & Gian Paolo Fadini comment on:
Revisiting the burden and patterns of #myocardial #infarction in type 1 #diabetes www.thelancet.com/journals/lan... #T1D #MI #CVD

#MedSky #EndoSky #CardioSky

Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation myocardial infarction in type 1 diabetes in Finland: a nationwide cohort study We report that STEMI and NSTEMI exhibit different incidence patterns depending on age and year of myocardial infarction. STEMI and NSTEMI also differed regarding risk profiles, demonstrating that myoc...

New—Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation #myocardial #infarction in type 1 #diabetes in Finland: a nationwide cohort study www.thelancet.com/journals/lan... #T1D #MI #CVD

#MedSky #EndoSky #CardioSky

Medical professional and patient. Expertise shared on cardiovascular care research

In case you missed it, check out our latest piece highlighting the sex-specific differences in cardiovascular disease onset, presentation, and outcomes lumanity.com/perspectives...

#CardiovascularDisease #RWE #CVD

Additional benefits of combining GLP-1 receptor agonist use with lifestyle modification GLP-1 receptor agonists have largely contributed to revolutionising pharmacological therapy of type 2 diabetes. They are among the most potent glucose-lowering agents, while also eliciting bodyweight ...

Stefano Del Prato & Anna Solini comment on:
Additional benefits of combining #GLP-1 receptor agonist use with #lifestyle modification www.thelancet.com/journals/lan...
#T2D #CVD

#MedSky #EndoSky #CardioSky