Spandidos Publications: Molecular and Clinical Oncology International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

What if low oxygen helps explain glioma treatment response?

In C6 glioma cells, amitriptyline reduced viability, proliferation, and PD-L1, but the response became more complex with temozolomide and radiation. HypoxyLab helped by maintaining cultures at 2.5% O2.

#Glioma #Hypoxia #CancerResearch

Radiomics-based models versus traditional imaging characteristics in the diagnostic grading of gliomas: A comparative study Introduction: Gliomas were highly aggressive primary brain tumors that require precise grading for effective treatment planning. Current grading relies on histopathological analysis, which can be inv...

#MRI #MachineLearning #Glioma #DiagnosticAccuracy #Radiomics #TumorGrading

www.archivesofmedicalscience.com/Radiomics-ba...

At the @ismrm.bsky.social workshop in Madrid this year, we examined #FTB maps in stereotactic biopsies, #DeltaT1 maps in #LITT, and structural-functional connectomic maps in preoperative assessments for supramarginal rsxn eligibility in #glioma surgery. And paella. @medicalcollegeofwi.bsky.social

Publications — GLIORESOLVE

📣Check out the latest publications from GLIORESOLVE labs www.glioresolve.eu/publications From tumour microenvironment insights to new therapeutic strategies...
Perfect weekend reading 🧠 #glioma #cancerresearch 🔬 @annagolebiewska.bsky.social @linqianweng.bsky.social @bergerslab.bsky.social

In the article, @breuniglab.bsky.social explains the advantages of organoids for rare conditions, including how his lab used brain organoids to identify a potential therapeutic applicable to 50% of pediatric #glioma patients, with a clinical trial in the works.

Gene Expression Profile Identifies LncRNA AL355974.3 As a Potential Glioma Biomarker

This study investigates #lncRNA expression in #Glioma tissue, functions of differentially expressed lncRNAs, their roles in #Tumor progression, & their potential to inform future research to identify #Biomarkers for diagnosis and treatment. #medsky

To read: doi.org/10.1007/s115...

SRSF3 promotes the generation of XBP1s to stabilize autophagy and enhance hypoxia adaptation in glioma - PubMed Hypoxia is a key driver of glioblastoma (GBM) progression. Serine/arginine-rich splicing factor 3 (SRSF3) is associated with the malignant progression of GBM, but its role in the hypoxic microenvironment of GBM remains unclear. This study aimed to explore the regulatory role and molecular mechanisms …

#SRSF3 promotes the generation of #XBP1s to stabilize autophagy and enhance hypoxia adaptation in #glioma | pubmed.ncbi.nlm.nih.gov/41778901/ | #openaccess #academicsky #medsky

Open access.

#Radiofrequency #Radiation #Glioma

pmc.ncbi.nlm.nih.gov/articles/PMC...

Evolution and adaptation of improved adenoviral platforms for the treatment of glioblastoma at Cardiff University on FindAPhD.com PhD Project - Evolution and adaptation of improved adenoviral platforms for the treatment of glioblastoma at Cardiff University, listed on FindAPhD.com

Looking for an awesome new PhD student, working at the intersection of #Virology and #Cancer research, looking to develop new therapies for #Glioma #Glioblastoma. Stipend, consumables and fees (UK/EU rates only) covered. #BeAVirusTinkerer #VITAL #TeamWAVU

www.findaphd.com/phds/project...

🙌 Insightful discussions today in Bucharest at the #EANO Tumor Board 2026. Real-world cases and expert lectures highlighted the importance of multidisciplinary collaboration in improving care for patients with #glioma.
Supported by an unrestricted educational grant from Servier. #NeuroOncology

Building better #CART cells. Finding more effective #glioma therapies. Accelerating #Alzheimersdisease biomarker discovery. All of these were the work of researchers like you. All were once impossible...until they weren't. So what “impossible” thing will you do next? https://bit.ly/3OsMGpW

📅 Mark your calendars! Abstract submissions for #EANO2026 are due April 2. Don’t miss your chance to showcase your #NeuroOncology research this September! 🔬 Submit now: eano.eu/eano2026/abs...

#btsm #neurosurgery #glioma #RadOnc #BrainCancer #cancernurse #AHP @jmwerner.bsky.social

This study identified PDCD2 as a prognostic #Biomarker in #Glioma, showing that its overexpression promotes tumor progression and correlates with malignancy & poor survival, marking it as a potential #TherapeuticTarget.

#OpenAccess: doi.org/10.1016/j.ge...

Diagram depicting brain tumors as nested ecosystems. Four concentric bowls represent cellular, tissue, body, and environmental levels. A second panel lists three features of nested ecosystems: diversity with spatial and temporal variation, intersectional communication within and between levels, and dynamic adaptation to external influences.

In their Perspective, Lori Forster and @gutmannlab.bsky.social apply the nested ecosystems concept to #glioma, clarify how diverse risk factors shape CNS oncobiology, and highlight new opportunities for targeted disease‑mitigation strategies.

Read: doi.org/10.1242/dmm....

Australian trial of personalised vaccines to treat children with deadly brain cancers A world-first clinical trial will test cancer vaccines designed specifically for children with advanced or treatment-resistant brain tumours, following a $2.578 million investment from the Australian ...

Australian trial of personalised vaccines to treat children with deadly brain cancers. news.uq.edu.au/2026-02-aust...

#Cancer #Brain #Paediatric #Pediatric #Australia #Medulloblastoma #Ependymoma #Glioma #Oncology #mRNA #Genome #Genetics #DNA #AcademicSky #AcademicChatter #ClinicalTrial #Vaccine

Risk Factors and Predictive Nomogram for Survival in Elderly Patients with Brain Glioma

#Nomograms built from #SEER data identify age, marital status, histology, stage, treatment, and #tumor location as key prognostic factors in elderly #glioma, accurately predicting survival and aiding risk stratification for clinical decision-making.

Read: doi.org/10.1007/s115...

This study identifies a BiP–FKBP9 axis that stabilizes FKBP9 to drive #glioma progression, linking high coexpression to poor prognosis and highlighting a promising therapeutic target to suppress #tumor growth and improve survival.

#OpenAccess: doi.org/10.1016/j.ge...

This #SystematicReview and Meta-analysis compared efficacy and safety of combining #bevacizumab with re-irradiation versus bevacizumab alone in recurrent high-grade #glioma:
journals.sagepub.com/doi/full/10....

APC is recruiting a Postdoc to work with @lilykeane.bsky.social at UCC on a project focusing on how early-life microbiome perturbations shape brainstem microglial development during the neonatal period.
#microbiome #glioma #cancer #jobfairy #researchjobs #ucc
Full Details: bit.ly/4tlQjxO

Neuro Oncology Research Summary January 2026 - Summarized Science Summary of key Neuro Oncology publications highlighting major findings, clinical relevance, and emerging research trends.

🧠 Neuro-Oncology — Jan 2026

• Spatial multi-omics reveals microenvironmental niches in glioma
• Germline risk variants refine glioma susceptibility
• CD47 destabilization and macrophage subsets expand immunotherapy angles

#NeuroOncology #Glioma #BrainTumors

pir.sh/nKzaEOK1Jp

APC is recruiting a Postdoc to work with @lilykeane.bsky.social at UCC on a project focusing on how early-life microbiome perturbations shape brainstem microglial development during the neonatal period.
#microbiome #glioma #cancer #jobfairy #researchjobs #ucc
Full Details: bit.ly/4tlQjxO

Discovery of unique brain tumor subtypes offers hope for targeted glioma therapies Researchers have uncovered the mechanisms behind three unique subtypes of mismatch repair deficient high-grade gliomas. The findings provide a clearer understanding of how these tumors develop, explai...

Discovery of unique brain tumor subtypes offers hope for targeted #glioma therapies
#Health #Neurology #Cancer

🔷 The randomized study is designed to assess efficacy and safety versus placebo, with progression-free survival (PFS) as the primary endpoint.

🔗 Read more: bit.ly/ONCOnews10Fe...

#ONCOnews #OncoAlert #OncEd #Glioma #Phase3Trial #ClinicalTrials #Oncology #NeuroOncology #TargetedTherapy

New research shows how a tumor metabolite (2HG) can make aggressive glioma cells less invasive and more sensitive to treatment, with the support of NANBIOSIS infrastructure.
More👉 www.nanbiosis.es/how-a-tumor-...

#CEBS #CEBiomedS #ICTSnews #NanbiosisExpertise #WorldCancerDay #Glioma #Glioblastoma

LinkedIn This link will take you to a page that’s not on LinkedIn

🔬 Themes:
Role of gut microbiome on primary and secondary (metastasis) brain tumours; Mechanisms of interaction between gut microbiome-derived factors and the tumour microenvironment and much more!!!

#GutBrainAxis #Microbiome #Glioblastoma #Glioma #CancerResearch #NeuroOnco

APC is recruiting a Postdoc to work with @lilykeane.bsky.social at UCC on a project focusing on how early-life microbiome perturbations shape brainstem microglial development during the neonatal period.
#microbiome #glioma #cancer #jobfairy #researchjobs #ucc
Full Details: bit.ly/4tlQjxO

Thanks, BrainLife.org, for the highlight:

www.brainlife.org/fulltext/202...

#glioma #glioblastoma #braintumor #neurosurgery #CNS #neurooncology #astrocytoma #oligodendoglioma

Recently published in @cp-immunity.bsky.social: Spatial immune profiling defines a subset of human gliomas with functional tertiary lymphoid structures. 👉 Full article:
www.cell.com/immunity/ful...

#NeuroOncology #Glioma #OpenAccess #EANOessentials

Survival Analysis of Patients Undergoing Intraoperative Contrast enhanced Ultrasound in the Surgical Treatment of Malignant Glioma

Scientists show that #ICEUS improves #ResidualTumor detection during malignant #glioma surgery and is linked to better overall and #ProgressionFreeSurvival, highlighting ICEUS as a #prognosticfactor and tool to enhance surgical outcomes.
Read: doi.org/10.1007/s115...

HMGN2 regulates H3K27ac of the CDC20 promoter region, enhancing its transcription to drive #Glioma cell proliferation, thus positioning HMGN2/CDC20 axis as potential #Biomarkers & #TherapeuticTargets in glioma.

#OpenAccess: doi.org/10.1016/j.ge...