Very happy to be in Bristol to present our work on #bacterial #omics in #hepatocellular #carcinoma!
Oral presentation O3 at the HCC-UK 2026 Congress.
Roger Williams Inst. of Liver Studies
@kingscollegelondon.bsky.social
#hcc #liver #cancer #livercancer #gut #microbiome #microbiota #hccuk2026
🌅 #Research #Alert
Regulatory #mechanisms of ALKBH5/CIITA axis in the #synergistic modulation of #hepatocellular #carcinoma #radiotherapy and #immunotherapy
#livercancer #liver #cancer #immunology
@springernature.com #Genes & #immunity
www.nature.com/articles/s41...
#Research
#Hic_5 promotes the progression of #nonalcoholic #steatohepatitis by regulating #hepatocellular fatty acid #metabolism through the #PTEN/PGE2/EP4 axis doi.org/10.1186/s435...
#NonalcoholicSteatohepatitis #HepaticStellateCell #hepatocytes
#Metal-drug self-delivery nanomedicine alleviates tumor immunosuppression to potentiate synergistic chemo/chemodynamic therapy against hepatocellular carcinoma. The new study was published in Fundamental Research: https://ow.ly/pQ8O50XQz8c
#Hepatocellular #carcinoma #nanomedicine #Chemotherapy
Patients with different CARS levels have different responses to therapies. A total of 373 HCC samples were divided into high- and low-CARS groups based on the median value, and the IC50 values for different drugs were estimated for each HCC patient according to a pipeline from the Genomics of Drug Sensitivity in Cancer (GDSC) database (A–C). (A) For sorafenib, CARShigh patients have significantly higher IC50 values than CARSlow patients. (B) For tamoxifen, CARShigh patients have significantly lower IC50 values than CARSlow patients. (C) For docetaxel, CARShigh patients have significantly lower IC50 values than CARSlow patients. (D–F) The “TIDE” algorithm was applied to assess the T cell exclusion and T cell dysfunction levels in HCCs. (D) Higher CARS is associated with lower TIDE scores. Lower TIDE scores indicate greater sensitivity to ICI therapy. (E) CARShigh patients experience significantly less loss of T-cell function compared to CARSlow patients. (F) CARShigh patients exhibit higher levels of T-cell exclusion grade in tissue than CARSlow patients.
An Early View: Single-cell transcriptomics in #hepatocellular #carcinoma identifies a rare cancer stem-like cell population and Cancer Stem-like Cell Risk Score (CARS).
Higher CARS predicted poorer survival, increased drug resistance and drug sensitivity.
🔗: onlinelibrary.wiley.com/doi/10.1111/...
🌅 #Research #Alert
#Radiotherapy combined with anti-PD-1 #immunotherapy promotes #ferroptosis-driven control of #hepatocellular #carcinoma
@springernature.com #Genes & #Immunity
www.nature.com/articles/s41...
Benign additional #liver masses frequently occur in dogs with primary liver masses. 🐕 Open access article: jav.ma/liver @ohiostatemed.bsky.social #hepatocellular #biopsy #malignant #benign
Dr. Yan Li from #USTC #Hefei #China talks on therapy for #Hepatocellular #Cancer / #HCC. #CXCR1 #nanobody approach to treat HCC & other cancer types. Focused on effects on NK cells. CXCL8 is the ligand. #WIC2025 #SITC2025
Post-translational #acylation modulates #immunosuppression and #immunotherapy #efficacy in #hepatocellular #carcinoma
#livercancer
#Genes & #immunity @springernature.com
www.nature.com/articles/s41...
#TUG1 targeting enhances #anticancer #immunity thereby facilitating #lenvatinib efficacy in #hepatocellular #carcinoma
#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Espervita's EVT0185: A Game Changer in Liver Cancer Immunotherapy #United_States #Ann_Arbor #Espervita #EVT0185 #Hepatocellular
📢Welcome to read: #Proteoform Patterns in #Hepatocellular Carcinoma Tissues: Aspects of #Oncomarkers, by Elena Zorina et al.
🔗See details at mdpi.com/2227-7382/13/3/27
#proteomes #proteomics #hepatocarcinoma #2D-electrophoresis #OpenAccess
Conducted by Chongqing University Cancer Hospital and published in Genes & Diseases on March 28, 2024, the study investigates the role of stromal interaction molecule 1 (STIM1) in sorafenib resistance.
#Hepatocellular carcinoma
Details: doi.org/10.1016/j.gendis.2024.101281
Greater adherence to the #Mediterranean diet was associated with a reduction in the risk for #obesity-related #cancers, particularly #hepatocellular, #kidney, and #colorectal cancers. www.medscape.com/viewarticle/...
The ➡️Translational research in hepatic oncology group⬅️ led by Josep M. Llovet has defined the molecular and immunological classification of #hepatocellular carcinoma and has characterised certain therapeutic targets
👉 https://i.mtr.cool/fbkkekcson
The ➡️Translational research in hepatic oncology group⬅️ led by Josep M. Llovet has defined the molecular and immunological classification of #hepatocellular carcinoma and has characterised certain therapeutic targets
👉 https://i.mtr.cool/fbkkekcson
📌 Our new paper out now on #AnnalsofSurgicalOncology !!!
💥 Hierarchically Positioning Laparoscopic Microwave Ablation in the Therapeutic Span of Early #Hepatocellular Carcinoma: A Real-Life Comparative Analysis
link.springer.com/article/10.1...
#GISeries: #Hepatocellular Ca 2/4: 2nd Line Treatment and when to switch!
🌟IO, TKIs, #supponc in 2L
🌟AEs/Management
Full 🗣️
- Oncbrothers.com/hcc-advanced...
- cor2ed.com/hcc-connect/...
- Also on “Oncology Brothers” podcast
#OncSky #MedSky #gism
@arndtvogel.bsky.social
#Hepatocellular Cancer series(1/4): Unressectable HCC w/ Dr. Rachna Shroff
🌟IO/IO combos (VEGF or CTLA4) 1L
🌟AEs/Management
Full 🗣️
- oncbrothers.com/hcc-advanced...
- cor2ed.com/hcc-connect/...
- Also on the “Oncology Brothers” podcast
#OncSky #MedSky @rachnatshroff.bsky.social #gism
"Certain dietary habits such as ... #coffee and #tea drinking were linked with a lower risk [of #hepatocellular #carcinoma], according to a large Mendelian randomization study from China." http://bit.ly/3QlRWIr http://bit.ly/3mMmzsV
