Dan Schieffer, Scientific Director of DeNovix, standing in front of a poster at SOT 2026
Come stop by poster board A150 to hear Dan chat about our machine learning-based algorithm for the automated counting of #hepatocytes!
#2026SOT #SOT2026 #ToxExpo #ToxExpo2026
Visit our poster at SOT / ToxExpo 2026!
You're invited to attend our poster session at #SOT2026!
Data sets were generated independently by internal DeNovix scientists and collaborating scientists from #BioIVT.
Learn more about counting hepatocytes on CellDrop: go.denovix.com/sm-hepatocyt...
#2026SOT #Hepatocytes
#Research
#Hic_5 promotes the progression of #nonalcoholic #steatohepatitis by regulating #hepatocellular fatty acid #metabolism through the #PTEN/PGE2/EP4 axis doi.org/10.1186/s435...
#NonalcoholicSteatohepatitis #HepaticStellateCell #hepatocytes
Fatty degeneration of hepatocytes (fatty hepatosis) #hepatology #hepatocytes #liver #liverhealth ... Continue to: www.facebook.com/reel/2566976...
📰New & Featured | A paper from #Nature suggests that #liver can be temporarily repurposed to restore immune signals that decline with age and enhance T-cell function in aged mice
🔸Delivering #mRNAs that encode #DLL1, #FLT3L and IL-7 to #hepatocytes expand #lymphoid progenitors
A LEGO-like liver model! 👷 Researchers generated patient-specific periportal liver assembloids from #hepatocytes, cholangiocytes, and liver mesenchymal cells that can be used to investigate human liver pathophysiology.
@mpi-cbg.de @merihuchlab.bsky.social @labshevchenko.bsky.social
Single cell transcriptomic analysis on six primary human hepatocytes
Cell Regen Report | Validating quality standards for primary human hepatocytes! ✅ Tested viability, markers & metabolism in hepatocytes, revealing heterogeneity for liver studies. #Hepatocytes #CellBiology
🔗 More at: doi.org/10.1186/s136...
On the left, a counted Hepatocytes sample. On the right, a counted Organoids sample. Both samples were counted using machine learning-based algorithms on the CellDrop Automated Cell Counter.
Complex cell samples, simple counting solution.
Learn more about the development of our machine learning based apps on the CellDrop Automated Cell Counter!
www.the-scientist.com/machine-lear...
#Organoids #Hepatocytes #BioSky
💫NEW: X. Du, W. Li, G. Li, C. Guo et al. report that dietary galactose regulates the cellular crosstalk between #hepatocytes and CD8+ #Tcells via IGFBP-1 production and IGF-1 signaling, thereby modulating T cell exhaustion and #antitumor immunity.
👉https://rdcu.be/eBW1z
bit.ly/4mU4qpX
Congrats to our PIs @masslab.bsky.social & #HasenauerLab on their latest work uncovering the crosstalk between #Kupffer #Cells and #Hepatocytes in the context of maternal obesity.
A great example of macrophage-driven communication shaping tissue physiology
👇 #Macrophages #Liver #Crosstalk
Huo, Wang et al. reveal that #adipocytes experiencing endoplasmic reticulum stress secrete #ceramide in lipoprotein form to #hepatocytes, activating the unfolded protein response by reducing membrane fluidity. rupress.org/jcb/article/...
#ER_literature
We are thrilled to present our new story on #neonatal #liver #macrophages and how they crosstalk with #hepatocytes during this early stage of life
👇
New from Dr. Marco De Giorgi and the @bill-lagor-lab.bsky.social: a new technique can selectively expand gene-edited #hepatocytes in mice in vivo.
Read the paper: bit.ly/4hHE4oV
Listen to discussion: bit.ly/4k42YAG
Researchers at @uniheidelberg.bsky.social discovered that #PROX1 can block #CellFate plasticity in #hepatocytes, preventing #LiverCancer in mice.
@aryankamal.bsky.social
@moritzmall.bsky.social
📃 @naturegenet.bsky.social - go.nature.com/3D9AYuR
🎤 - bit.ly/4k42YAG
When even an optimized traditional algorithm struggled to count #hepatocytes well, we decided that it was time for a better solution.
We worked with experts in the field to develop the first machine learning based algorithm for counting hepatocytes.
Learn more: https://buff.ly/4hbEofc
#BioSky
Histological examination of the livers unveiled that Orc2 deletion correlated with the presence of fewer, yet larger nuclei and cells. Our flow cytometry analysis further substantiated that Orc2 deletion promotes endo-reduplication in #hepatocytes.
