Amazing 3 days of intensive deeping into #Hypertrophic #Cardiomyopathy at @escardio HeartHouse for the #EAPC_ESC #HCM course: Thank you @mauripieroni72 & @gherardobis for inviting me! Great days w @IacopoOlivotto @LuisRLopes77 @chiarabd @VDelgadoGarcia @SSharmacardio Roddy Walsh 🇪🇺 🇺🇦
In a study published in Burns & Trauma, a research team reports a novel three-dimensional culture platform that enables long-term expansion of functional dermal papilla cells and the production of therapeutically potent extracellular vesicles.
#hypertrophic scar
Details: doi.org/10.1093/burn...
HCM and Young Black Athletes: Essential Insights for Parents and Coaches Did you know that hypertrophic cardiomyopathy (HCM) is a leading cause of sudden cardiac death (SCD) in young athletes? Yup,...
#Hypertrophic #Cardiomyopathy #(HCM)
Origin | Interest | Match
#β2Microglobulin upregulation in #hypertrophic #adipocytes drives CD8+ T cell activation, iron overload, #ferroptosis, and M1 #MacrophagePolarization, while its ablation or knockdown alleviates obesity-linked inflammation and metabolic disorders.
#STTT: doi.org/10.1038/s413...
Elevated #β2Microglobulin in #hypertrophic #adipocytes activates CD8+ T cells, triggers adipocyte #ferroptosis, and promotes #macrophage M1 polarization, driving obesity-linked #inflammation and #MetabolicDisorders.
#OpenAccess in #STTT: doi.org/10.1038/s413...
Inflammation-Related Factors S100A9 and TLR2 in Cardiomyocyte Hypertrophy
A pathogenic S100A9–TLR2 feedback loop amplifies #hypertrophic and #InflammatorySignaling in mechanically stressed #cardiomyocytes, linking immune dysregulation to maladaptive #CardiacRemodeling and highlighting a therapeutic target in #HeartFailure.
Read: doi.org/10.1007/s115...
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Key events in this evolution include the identification of #sarcomeric variants as an important cause of #hypertrophic #cardiomyopathy and the continuing development of therapeutic #myotropes.
The Critical Understanding of Hypertrophic Cardiomyopathy in Young Athletes #USA #Mission,_Kansas #HCM #Cardiomyopathy #Hypertrophic
#PaulKornerSeminar speaker Dr Jane Yu unveils one of the key molecules that drives cardiac #hypertrophic signaling in response to pressure overload. #CardiovascularDisease #Mechanobiology #ScienceTwitter