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#Ionchannels
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3 full days of #Mechanobiology in 😎 Alicante
Only 5 weeks left!
@garyrlewin.bsky.social @embo.org Lecture
Information and registration: 𝐡𝐭𝐭𝐩://𝐦𝐞𝐜𝐡𝐚𝐧𝐨𝟐𝟎𝟐𝟔.𝐮𝐦𝐡.𝐞𝐬/
mechano2026@manners.es
mechano2026@umh.es
#Piezochannels #IonChannels #Mechanosensation
#Hearing #Integrins #Wound_repair
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We're at the Membrane Physiology Symposium 2026 in Napa Valley! Meet 𝗔𝗺𝗯𝗲𝗿 𝗝𝗼𝗹𝗹𝘆 at the Meritage Resort & Spa to see how CorePlate™ HD-MEA platforms deliver high-resolution, label-free functional insights for neuronal and cardiac research.
#3Brain #MembranePhysiology #IonChannels #Electrophysiology
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What an incredible week in Marrakech! Proud to sponsor the 7th Channelopathy Meeting (March 25–29, 2026), the first held in Africa. Dinesh Srinivasan presented our #SGK1 inhibition research for LQTS and beyond. 🧬❤️
🔗 https://channelopathy2026.org
#Channelopathy #IonChannels
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Combining elastic network models and linear response theory as tool to understand the global dynamics in allosteric regulation of HCN channels. A new review by Magnus Behringer, Gerhard Thiel and colleagues @tuda.bsky.social rupress.org/jgp/article/...
#IonChannels
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PRF Spotlight Series Ep 2- Dr. Stephen Waxman of Yale University shares with Drs. Isaac Aragão & Beatriz Adjafre the history of the Nav channels and their role in pain, his ideas for the future and sage advice for young investigators. bit.ly/48C9KcK #pain #science #ionchannels @iasp.bsky.social
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One week left to apply for the EMBO/FEBS lecture course on #ionchannels and #transporters in beautiful Erice in May 2026:
meetings.embo.org/event/26-ion...
Please share
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Beat-locked ATP microdomains in the sinoatrial node map a Ca2+-timed energetic hierarchy and regional pacemaker roles. New study from Manuel F. Muñoz, Fernando Santana @lfsantana68.bsky.social and colleagues @ucd-physiology.bsky.social rupress.org/jgp/article/...
#IonChannels #CardiacMuscle
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Check out this great review by Osama Harraz et al., Brain Capillary Ion Channels: Physiology and Channelopathies
➡️ https://ow.ly/Jenc50YCOSA
#BrainCapillaries #IonChannels
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Behringer et al. from @tuda.bsky.social show how coarse-grained computational methods uncover long-range mechanical connectivities in HCN #IonChannels. Together with high-res #cryoEM structures, these methods provide insights into their allosteric regulation. rupress.org/jgp/article/...
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📣 Call for Papers! 📣 We welcome papers on Voltage-Gated Sodium Channels for a special issue, initiated in the context of the second Worldwide Sodium Channel Conference #WSCC26 in Switzerland, February 4 - 6, 2026. Submit here 👉 rupress.org/jgp/pages/ca...
#IonChannels #CallForPapers
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This summer, explore the intricate molecular mechanisms of vascular ion channels to their influence on complex physiological functions:
📆 27 – 28 August
📍 University of Oxford, UK
From discussing discoveries to the development of therapies, join us at our #IonChannels meeting ⬇️
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Deep learning as a generator of sodium channel state hypotheses. Lisa Schmidt and Wojciech Kopec @mpi-nat.bsky.social discuss recent work by Lopez-Mateos, Narang, and @vyy-sf.bsky.social @ucd-physiology.bsky.social (rupress.org/jgp/article/...) in Commentary: rupress.org/jgp/article/...
#IonChannels
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Sequential membrane remodeling by #cholesterol distinctly modulates HCN channels in naïve & neuropathic DRG neurons. New study by Lucas J. Handlin, Gucan Dai (@gucandai.bsky.social) et al (Saint Louis University School of Medicine): rupress.org/jgp/article/...
#lipids #Biophysics #Pain #IonChannels
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📢 If you are working at the intersection of #ionchannels and #transporters in #immunity, we invite you to join us and share your research. We look forward to seeing you at #CTImmSRC #FASEB Conference in #NiagaraFalls
👉 events.faseb.org/event/7cca57...
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🧫Just published online in JPS❣️ (📖 Open Access!! 14 March 2026)
“Dynamic Regulation of TASK-1 Channels Under Cellular Stress”
— Yang Yu et al.
🔗 doi.org/10.1016/j.jp...
#IonChannels #CellStress #TASK1 #Electrophysiology #NowOnline #JPhysiolSci
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#Cholesterol in cell membranes plays a key role in controlling how #pain-sensing #neurons respond. Handlin et al. show that distinct cholesterol pools—OMD-associated & freely accessible cholesterol—differently influence HCN #IonChannels, which regulate nerve excitability. rupress.org/jgp/article/...
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#Cholesterol in cell membranes plays a key role in controlling how #pain-sensing #neurons respond. Handlin et al. show that distinct cholesterol pools—OMD-associated & freely accessible cholesterol—differently influence HCN #IonChannels, which regulate nerve excitability. rupress.org/jgp/article/...
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Opening of rod #photoreceptor CNG channels by photodynamically generated singlet oxygen. New study from Gaogao He, Lei Zhou and colleagues (Shenzhen Bay Laboratory): rupress.org/jgp/article/...
#Biophysics #MolecularPhysiology #IonChannels
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Commentary @jgp.org: Schmidt and Kopec @mpi-nat.bsky.social discuss how Lopez-Mateos et al. @vyy-sf.bsky.social (rupress.org/jgp/article/...) used AlphaFold 2 to generate structural ensembles of voltage-gated sodium channels across different conformations. rupress.org/jgp/article/...
#IonChannels
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Commentary: Schmidt and Kopec @mpi-nat.bsky.social discuss how Lopez-Mateos et al. @vyy-sf.bsky.social (rupress.org/jgp/article/...) used AlphaFold 2 to generate structural ensembles of voltage-gated sodium channels across different conformations. rupress.org/jgp/article/...
#IonChannels
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#Antiverse #AI #AIantibodyplatform #biotech #drugdiscoveryprogrammes #antibodybasedtherapeutics #antibodies #drugtargets #Gproteincoupledreceptors #GPCR #ionchannels #NxeraPharma #GPCRs #cellularcommunication #transmembraneprotein #Tcellreceptor #TCR #antiPD1antibodies #drugdiscovery
zurl.co/cAKcg
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Gaogao He, Lei Zhou et al. demonstrate that #ionchannels from #photoreceptors in the retina are very sensitive to photodynamic modification mediated by singlet oxygen, ¹O2, the molecular oxygen in electronically excited states. rupress.org/jgp/article/...
#Biophysics #MolecularPhysiology
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In @jgp.org, Gaogao He, Lei Zhou et al. demonstrate that #ionchannels from #photoreceptors in the retina are very sensitive to photodynamic modification mediated by singlet oxygen, ¹O2, the molecular oxygen in electronically excited states. rupress.org/jgp/article/...
#Biophysics
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More details on Dravet Syndrome 🧪🧠💊:
What is Dravet Syndrome?
#ionchannels
dravetfoundation.org/what-is-drav...
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📣 Call for Papers 📣 JGP welcomes submissions that focus on increasing our understanding of the role of voltage-gated sodium channels in the broad physiological and pathophysiological context. 👉 rupress.org/jgp/pages/ca...
#IonChannels #CallForPapers #WSCC26
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🗓️📌 Get your virtual seat for our first webinar of 2026 events.teams.microsoft.com/event/cb12ab...
Agenda | 1 Hour
🗓️ Wednesday 18 March | 1:30 – 2:30 PM CET
📍 Online
#Neuroscience #VirtualLabs #DigitalBrainModels #NeuronModeling #IonChannels
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🙂 Happy to share our contribution to improving the understanding of #ionchannels! In this review, the authors attempt to elucidate how the modulator pocket contributes to #K2P channel activation. #TREK1 #MD #C-type inactivation #ML335 #review @wojciechkopec.bsky.social
👉 doi.org/10.1080/1933...
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Structure-function analysis of the lithium-ion selectivity of the voltage-gated sodium channel. New study from Yuki K. Maeda, Katsumasa Irie and colleagues (Wakayama Medical University): rupress.org/jgp/article/...
#Biophysics #IonChannels
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Did you know that @ninds is developing an RM1 funding mechanism to support team science focused on a single goal?
Just learned about it in the "Inside NIH" session organized by the Advocacy Committee at #BPS2026.
Coming soon at #nih.
#Biophysics #neuroscience #ionchannels
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