1/19 During the non-mated phase when females were actively hunting and eating, they produced #high #levels of #neuropeptides, or small protein molecules used by #neurons to #communicate with each other that have been linked to feeding behavior in many animals.
R.I.P., Susan E. #Leeman [°May 9, 1930 – Jan. 20, 2026]🕯️😌🌹
#endocrinology #neuroendocrinology #peptides #neuropeptides #neurotensin #SP #SubstanceP #CRF #CorticotropinReleasingFactor #saliva #UMassChanMedicalSchool #DoraGubernikoff #SusanEpstein #SusanLeeman
ONJCRI researchers have linked two nervous system components to bowel cancer growth, creating promising new avenues for treatment with existing approved migraine therapies.
The findings were published in The BMJ Oncology today.
➡️ https://ow.ly/PCFE50XfWVh
#BowelCancer #Neuropeptides #ONJCRI
🏅Proud “Winner of The Biomedicines Hot Paper #Award!🏆 Shocking fact: #Orexin #Neuropeptides run our #Vigilance, #Stress & #Metabolism!😱🚀Our review unveils their evolution & drug prospects 🧠📈🌟 @mdpiopenaccess.bsky.social
#Neuroscience #HotPaper
Dive in now!
www.mdpi.com/2227-9059/12...
Comes with 24 new venom transcriptomes, discovery of venom insulins with activity at the human receptor, new natriuretic peptides observed across a wide range of animals, and new insights into the neuropeptide diversity in venoms.
#PeptideDrugDiscovery #Neuropeptides #Venoms #DrugDiscovery #Insulin
We’ve made it to Bluesky! Stay tuned to hear about our latest research on the role of neuropeptides in human health and disease. We look forward to connecting with you all!
#Peptides #Neuropeptides #MedicinalChemistry #DrugDiscovery #AcademicSky
#Neuropeptides essential for complex social behavior with phenotypic plasticity in social insect model doi.org/10.1016/j.ce... #SocialAnalysis #SocialHierarchy #TranslationalScience
📣 Online now - the Review "Molecular mimicry: ecology, evolution, and applications of doppelgänger peptides" from Thomas Koch, Samuel Robinson, and Helena Safavi-Hemami.
#MolecularMimicry #Hormones #Neuropeptides #Semiochemicals #Toxins #Venoms
Read it here: authors.elsevier.com/sd/article/S...
🏅Proud “Winner of The Biomedicines Hot Paper #Award!🏆 Shocking fact: #Orexin #Neuropeptides run our #Vigilance, #Stress & #Metabolism!😱🚀Our review unveils their evolution & drug prospects 🧠📈🌟 @mdpiopenaccess.bsky.social
#Neuroscience #HotPaper
Dive in now!
www.mdpi.com/2227-9059/12...
Shocking fact: #Orexin #Neuropeptides run our #Vigilance, #Stress & #Metabolism!😱🚀Our review unveils their evolution & drug prospects 🧠📈🌟 Proud “Winner of The Biomedicines Hot Paper #Award!🏆 @mdpiopenaccess.bsky.social
#Neuroscience #HotPaper
Dive in now!
www.mdpi.com/2227-9059/12...
Open Access:
A case-control study provides evidence for the use of serum #neuropeptides as biomarkers for children with #migraine & differentiating pediatric migraine from non-migraine #headaches
headachejournal.onlinelibrary.wiley.com/share/Z9NSBN...
Sibğatullah Ali Orak MD et al
Autocrine and paracrine neuropeptidergic signaling at the Caenorhabditis elegans NMJ affects cholinergic transmission. The diagrams show the neuromuscular junction of C. elegans, with cholinergic and GABAergic motor neuron, as labeled, innervating dorsal and ventral muscle, respectively. Dyadic synapse of cholinergic neuron to GABAergic neuron and muscle. Note that the same innervation pattern exists from different sets of MNs, but with inverted topology (not represented in this graph). Also shown is the proprioceptive neuron DVA, that innervates cholinergic neurons along the ventral nerve cord (drawn more dorsal, for simplicity). Relevant ion channels and receptors are indicated on the left (NPR: neuropeptide receptor). The lefthand panel shows the situation in wild-type individuals. The righthand panel shows the situation in unc-31 (CAPS) or egl-3; aex-5 (pro-protein convertases, PCs) double mutants, where no mature neuropeptides are released or formed, thus the signaling steps induced by neuropeptides are absent.
Synaptic transmission is modulated by #neuropeptides in sensory systems & interneurons. This study shows that motor #synapses are also modulated by neuropeptidergic signaling, where lower ACh levels are compensated by upregulation of postsynaptic Ca2+ channels @plosbiology.org 🧪 plos.io/4d6Ecgg
Autocrine and paracrine neuropeptidergic signaling at the Caenorhabditis elegans NMJ affects cholinergic transmission. The diagrams show the neuromuscular junction of C. elegans, with cholinergic and GABAergic motor neuron, as labeled, innervating dorsal and ventral muscle, respectively. Dyadic synapse of cholinergic neuron to GABAergic neuron and muscle. Note that the same innervation pattern exists from different sets of MNs, but with inverted topology (not represented in this graph). Also shown is the proprioceptive neuron DVA, that innervates cholinergic neurons along the ventral nerve cord (drawn more dorsal, for simplicity). Relevant ion channels and receptors are indicated on the left (NPR: neuropeptide receptor). The lefthand panel shows the situation in wild-type individuals. The righthand panel shows the situation in unc-31 (CAPS) or egl-3; aex-5 (pro-protein convertases, PCs) double mutants, where no mature neuropeptides are released or formed, thus the signaling steps induced by neuropeptides are absent.
Synaptic transmission is modulated by #neuropeptides in sensory systems & interneurons. This study shows that motor #synapses are also modulated by neuropeptidergic signaling, where lower ACh levels are compensated by upregulation of postsynaptic Ca2+ channels @plosbiology.org 🧪 plos.io/4d6Ecgg
Autocrine and paracrine neuropeptidergic signaling at the Caenorhabditis elegans NMJ affects cholinergic transmission. The diagrams show the neuromuscular junction of C. elegans, with cholinergic and GABAergic motor neuron, as labeled, innervating dorsal and ventral muscle, respectively. Dyadic synapse of cholinergic neuron to GABAergic neuron and muscle. Note that the same innervation pattern exists from different sets of MNs, but with inverted topology (not represented in this graph). Also shown is the proprioceptive neuron DVA, that innervates cholinergic neurons along the ventral nerve cord (drawn more dorsal, for simplicity). Relevant ion channels and receptors are indicated on the left (NPR: neuropeptide receptor). The lefthand panel shows the situation in wild-type individuals. The righthand panel shows the situation in unc-31 (CAPS) or egl-3; aex-5 (pro-protein convertases, PCs) double mutants, where no mature neuropeptides are released or formed, thus the signaling steps induced by neuropeptides are absent.
Synaptic transmission is modulated by #neuropeptides in sensory systems & interneurons. This study shows that motor #synapses are also modulated by neuropeptidergic signaling, where lower ACh levels are compensated by upregulation of postsynaptic Ca2+ channels @plosbiology.org 🧪 plos.io/4d6Ecgg
Oxytocin is crucial beyond its role as the ‘love hormone’: Professor Inga Neumann explores oxytocin's role in shaping social behavior, stress response, and psychiatric treatment.
#Oxytocin #Neurobiology #SocialBehavior #EmotionalHealth #Neuropeptides #EarthDotCom #EarthSnap #Earth
Fascinating results here. Especially appreciate the multiple dosages and the time course in CSF and plasma, in addition to the behavioral results. #Neuropeptides #BehavioralEndocrinology
Mandatory introductory skeet(?): I am a psychologist, turned behavioral neuroscientist, turned electrophysiologist. Freshly minted PI with a negative ratio of ideas to resources.
Lab will work on how neuromodulatory signaling fine-tunes complex behaviors. We love #neuropeptides and the #bluespot
See our new paper on insect #neuropeptides: The Adipokinetic Hormone (AKH) and the Adipokinetic Hormone/Corazonin-Related Peptide (ACP) Signalling Systems of the Yellow Fever Mosquito Aedes aegypti: Chemical Models of Binding. #nmr #chemistry #biophysics https://www.mdpi.com/2704422
Looking forward to using the quote as a rationale for my next grant 🤣 If nothing is solved, everything can be novel.
#worms #neuropeptides #internal states #navigation #locomotion encoding #chemotaxis #thermotaxis #learning #... https://x.com/HenryYin19/status/1603093651877691392
