Original post on mastodon.social

🧬 #Epigenetik ist die Lehre von den vererbbaren Veränderungen der #Genexpression oder des #Zellphänotyps, die nicht mit Veränderungen der zugrunde liegenden #DNA-Sequenz einhergehen.
#Epigenetik #sflorg

https://mastodon.social/@sflorg/116071304685274102

#DNAMethylierung #Traumatisierung #Janov […]

Ferrara et al. review the growing evidence linking #vitaminD deficiency to #ADHD symptom severity and explore its potential as an adjunctive therapy through #neuroprotective and anti-inflammatory mechanisms. doi.org/10.4103/REGE... #MentalHealth #PublicHealth #MedSky #neuroskyence

Product Citation 🌟

Trichostatin A (TSA), commonly used in cancer studies, may also be #neuroprotective. In a neuronal model, TSA significantly improved cell viability in the presence of StressMarq's #AmyloidBeta 1-42 Oligomers.

Paper 🧩 https://bit.ly/4scYknu
Product 📚 https://bit.ly/4gYWkcj

Original post on mastodon.social

Epigenetik ist die Lehre von den vererbbaren Veränderungen der #Genexpression oder des #Zellphänotyps, die nicht mit Veränderungen der zugrunde liegenden #DNA-Sequenz einhergehen.
#Epigenetik #sflorg

https://mastodon.social/@sflorg/116071304685274102

#DNAMethylierung #Traumatisierung #Janov […]

Original post on mastodon.social

Epigenetik ist die Lehre von den vererbbaren Veränderungen der #Genexpression oder des #Zellphänotyps, die nicht mit Veränderungen der zugrunde liegenden #DNA-Sequenz einhergehen.
#Epigenetik #sflorg

https://www.sflorg.com/2026/02/cat02142601.html […]

Naringin and Naringenin: Potential Multi-Target Agents for Alzheimer’s Disease

An overview of the #Neuroprotective role of #Naringin and #Naringenin, elucidating their potency in targeting #AlzheimersDisease #Pathophysiology by modulating amyloid-β and #MetabolicDysfunction while addressing delivery limitations.

Read: doi.org/10.1007/s115...

Anti-inflammatory and DNA Repair Effects of Astragaloside IV on PC12 Cells Damaged by Lipopolysaccharide

This study highlights #AstragalosideIV as a potent #Neuroprotective agent reversing LPS-induced #DNAdamage in PC12 cells by mitigating #DNAdamage, downregulating key #Inflammatory mediators, and inhibiting the IL-17 signaling pathway.

Read: doi.org/10.1007/s115...

Marijuana's potential in neurodegenerative diseases: an editorial An official website of the United States government

Interestingly, emerging evidence suggests #Cannabis constituents possess #neuroprotective properties. Cannabinoids, through their interaction with the endocannabinoid system, have demonstrated anti-inflammatory, antioxidant, and anti-excitotoxic effects #Pubmed pmc.ncbi.nlm.nih.gov/articles/PMC...

Interestingly, emerging evidence suggests #Cannabis constituents possess #neuroprotective properties. Cannabinoids, through their interaction with the endocannabinoid system, have demonstrated anti-inflammatory, antioxidant, and anti-excitotoxic effects #Pubmed pmc.ncbi.nlm.nih.gov/articles/PMC...

IRF7-driven microglial #inflammation damages #neurons in #TemporalLobeEpilepsy by suppressing RORB–STIM1 signaling, highlighting IRF7 as a central regulator and promising #neuroprotective therapeutic target for drug-resistant TLE.

#OpenAccess: doi.org/10.1016/j.ge...

piece of cannabis in a hand and text with little pics Forms of intake Cannabis can be taken medicinally in various ways. In Switzerland, inhalation via the lungs and oral ingestion are particularly common. However, there are also other promising forms of medical use that will hopefully soon also be available to Swiss patients. ... https://medcan.ch/en/medical-information/intake

+++ Forms of intake +++ 🚭

🌱 #Cannabis can be taken ♿ medicinally in various ways. In 🇨🇭 #Switzerland, inhalation via the lungs and oral ingestion are particularly common. However, there are also other promising forms of 💊 medical use that will hopefully soon […]

[Original post on mastodon.social]

#Parkinson's isn't just tremors. To bridge the gap between symptoms and cures, our deep tech startup is moving 4 years of deep tech R&D into clinical trials for a #neuroprotective drug. Rigor and collective energy drive our mission to transform care.

Green-synthesis of chromium (III) nanoparticles using garden fern and evaluation of its antibacterial and anticholinesterase activities

This Open Chemistry study demonstrates the #GreenSynthesis and characterization of CrNPs using Adiantum capillus-veneris extract and highlights its potent #AntiBacterial activity and #Neuroprotective effects.
#OpenAccess: doi.org/10.1515/chem...

Insight into the Neuroprotective Mechanisms of Resveratrol: Inhibition of Alpha-Synuclein Fibrillation and its Role in Mitigating Toxicity - PubMed Insight into the Neuroprotective Mechanisms of Resveratrol: Inhibition of Alpha-Synuclein Fibrillation and its Role in Mitigating Toxicity

Insight into the Neuroprotective Mechanisms of Resveratrol: Inhibition of Alpha-Synuclein Fibrillation and its Role in Mitigating Toxicity.

https://pubmed.ncbi.nlm.nih.gov/41396370/

#neurodegeneration #pubmed #neuroprotective

Unraveling the potential of gasotransmitters as neurogenic and neuroprotective molecules: focus on Alzheimer's and Parkinson's diseases - PubMed Alzheimer's disease and Parkinson's disease are the two most prevalent neurodegenerative disorders worldwide, both characterized by progressive neuronal loss. Despite distinct pathophysiological featu

Unraveling the potential of gasotransmitters as neurogenic and neuroprotective molecules: focus on Alzheimer's and Parkinson's diseases.

https://pubmed.ncbi.nlm.nih.gov/41396689/

#neurodegeneration #pubmed #Alzheimers #neuroprotective #Parkinsons

Men Vs Women: Hormones, Health, and Biological Longevity In today's episode we're dissecting the biological disparities that give women a 5 to 10 year longevity advantage over men. We explore the buffering effects of estrogen, which is cardioprotective and neuroprotective, delaying heart disease and neurodegeneration. We also discuss how male androgens might accelerate aging and increase the risk of cardiovascular disease. Learn why men are statistically more vulnerable to metabolic syndrome and why optimizing fitness and body fat percentage is essential for reaching maximum lifespan. Reference: https://www.youtube.com/watch?v=BYzh9QTsCxc

📣 New Podcast! "Men Vs Women: Hormones, Health, and Biological Longevity" on @Spreaker #aging #androgens #biological #cancer #cardioprotective #centenarians #disease #estrogen #fitness #heart #hormones #immunity #lifespan #longevity #metabolic #mortality #neuroprotective #sex #testosterone

BioRxiv Article

[BioRxiv] Ischemic injury triggers a protective microglial phenotype in models of Aβ pathology

https://doi.org/10.64898/2025.12.09.692939

#neurodegeneration #biorxiv #amyloid #neuroprotective

BioRxiv Article

[BioRxiv] Plasmalogen-Independent Neuroprotection: Synthetic alkyl ether lipids activate signaling to mitigate neuroinflammation and enhance cognitive function

https://doi.org/10.64898/2025.12.08.693101

#neurodegeneration #biorxiv #neuroprotective #Alzheimers

Neuroprotective Effect of Melatonin in Original Rectal Suppositories in Experimental Acute Cerebral Ischemia in Rats - PubMed We studied the effect of melatonin in the original rectal suppositories on neurological status, microcirculation, and morphology of focal ischemic infarction in experimental acute cerebral ischemia mo

Neuroprotective Effect of Melatonin in Original Rectal Suppositories in Experimental Acute Cerebral Ischemia in Rats.

https://pubmed.ncbi.nlm.nih.gov/41171325/

#neurodegeneration #pubmed #neuroprotective

Unveiling the Neuroprotective Effect of Paraoxonase 1 in Neurodegenerative Diseases Focusing on Alzheimer's Disease.

https://pubmed.ncbi.nlm.nih.gov/41335160/

#neurodegeneration #neuroprotective #Alzheimers

The Buried Alzheimer Cure: DMSO Exposes the Billion-Dollar Amyloid Fraud In today's episode we're diving into the colossal failure of the amyloid hypothesis, which has wasted billions while relying partially on fraudulent research. Decades of NIH funding produced highly controversial drugs that cause severe brain damage like bleeding and swelling. We expose how this lucrative paradigm buried simple, affordable treatments that actually work. Learn about DMSO and MCTs (coconut oil), which have shown success in improving memory and cognitive function without dangerous side effects. We also review the actual causes and treatments for Alzheimer's and the neuroprotective power of DMSO. Resources: 1. https://www.midwesterndoctor.com/p/why-isnt-there-a-cure-for-alzheimers-d9d

📣 New Podcast! "The Buried Alzheimer Cure: DMSO Exposes the Billion-Dollar Amyloid Fraud" on @Spreaker #alzheimers #amyloid #brain #cognitive #dementia #dmso #drug #fda #fraud #health #industry #inflammation #mcts #memory #natural #neuroprotective #nih #research #scandal #therapy

Protective effect of green synthesized nanoceria on retinal oxidative stress and inflammation in streptozotocin-induced diabetic rat

This Open Chemistry study presents the #GreenSynthesis & characterization of #Rutin-mediated cerium oxide #nanoparticles (R-CeO2NPs), demonstrating that R-CeO2NPs exert a #Neuroprotective effect by mitigating #OxidativeStress & #Inflammation.

#OpenAccess: doi.org/10.1515/chem...

Learn about the #neuroprotective capabilities of the charismatic #mangosteen in this review from our latest issue 🌟

www.thieme-connect.de/products/ejo...

#GrowingTogether #BrainHealth #MedicinalPlants #NeuroProtection

Product Citation 💐

The APOE #Christchurch mutation shows selective #neuroprotective effects. StressMarq’s Mouse #AlphaSynuclein PFFs enabled an in vivo model to study the mutation’s impact on alpha synuclein and #tau pathologies.

Paper 🌸 https://bit.ly/43xksiy
Product 🌼 https://bit.ly/2HJyYee

Breaking Down the #Science of 🌱 #Cannabis and #Neuroprotection in the #UnitedStates
The conversation surrounding cannabis has evolved dramatically over the past few decades, ... of serious #research and medical advocacy. With a growing body of #evidence […]

[Original post on mastodon.social]

Diabetic neuropathy: cutting-edge research and future directions - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Diabetic neuropathy: cutting-edge research and future directions

This review explores the multifactorial pathogenesis of #DiabeticNeuropathy and highlights emerging diagnostics, #neuroprotective strategies, and therapeutic targets—including gene and #StemCellTherapies. #DiabetesMellitus #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

M102 activates both NRF2 and HSF1 transcription factor pathways and is neuroprotective in cell and animal models of amyotrophic lateral sclerosis - Molecular Neurodegeneration M102 is a central nervous system (CNS) penetrant small molecule electrophile which activates in vivo the NF-E2 p45-related factor 2-antioxidant response element (NRF2-ARE) pathway, as well as transcri...

'M102 activates both NRF2 and HSF1 transcription factor pathways and is #neuroprotective in cell and animal models of #AmyotrophicLateralSclerosis'

Amy Keerie, Raquel Rua Martins, Chloe Allen...Pamela J. Shaw, Laura Ferraiuolo, Richard J. Mead #ALS

bit.ly/4hEAdd6

Vitamin K Analogues May Help Transform the Treatment of Neurodegenerative Diseases｜Shibaura Institute of Technology SIT Shibaura Institute of Technology (Tokyo)

Supercharged Vitamin K could help the brain heal itself [via Shibaura Inst. of Tech] 🧪🥼🧠🩺⚕️

"findings highlight unique mechanisms underlying the #neuroprotective effects of #vitamin K and its analogues"

www.shibaura-it.ac.jp/en/headline/...

#analogues #brain #neurogenesis #health #medicine

Why does this matter?

Neurons expressing CaV1.3_43S are at risk of Ca²⁺ toxicity, e.g. in Parkinson’s, Alzheimer’s, and spinal cord injury.

RNA editing acts as a neuroprotective brake by dampening excessive Ca²⁺ influx.

#Parkinsons #Alzheimers #SpinalCordInjury #NeuroProtective

Product Citation: Proteomic analysis identified pyroxamide as a potential #neuroprotective agent in Parkinson's disease. StressMarq's #AlphaSynuclein A53T PFFs were used to examine its effects in an in vitro model of #PD.

Paper 💡 https://bit.ly/46XxV3O
#αSyn PFFs 🌐 https://bit.ly/2GREQ4c