Rethinking Antioxidants and Aging: When Do They Actually Work? In today's episode we're exploring the surprising truth about Antioxidants and Aging. For years, these supplements were hailed as miracles, then dismissed as useless or even harmful. We’ll reveal why your age determines if they help or hurt. While young people might blunt their exercise gains with supplements, those over 45 face a "tipping point" where oxidative stress becomes a wildfire. We discuss a major new study showing how specific precursors like GlyNAC can restore balance, boosting muscle strength and physical function when combined with exercise. References: - https://pmc.ncbi.nlm.nih.gov/articles/PMC12491480/ - https://pmc.ncbi.nlm.nih.gov/articles/PMC9879756/ Support our work: Make a small donation. This removes any advertisements and help us continue bringing more interesting topics and confronting mainstream narrative on health. Click the Link to support us: https://www.spreaker.com/podcast/foodnourish-deep-dives--6602003/support

📣 New Podcast! "Rethinking Antioxidants and Aging: When Do They Actually Work?" on @Spreaker #aging #antioxidants #biology #exercise #fitness #glutathione #glynac #health #longevity #muscle #nutrition #oxidative #recovery #research #science #strength #stress #supplements #vitality #wellness

Home-based #Exercise Improves #Muscle #Oxidative Capacity in #Kidney #Disease

#VisualAbstract by Husam Alzayer

www.kireports.org/article/S2468-0249(25)00...

Gwenaelle Begue Armin Ahmadi, PhD Bob Roshanravan

A mitochondrial protein may hold the secret to longevity As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health. This has drawn attention to the need to extend "healthspan," the perio...

Japanese researchers discover #mitochondria #protein linked to #longevity

medicalxpress.com/news/2025-12...

COX7RP:

— mitochondrial protein
— promotes respiratory #supercomplexes
— enhances #energy production
— reduces #oxidative #stress
— increases #mouse #lifespan

#health #science 🧪 #aging

Neonicotinoid Insecticides: The Unseen Threat to Male Fertility In today's episode we're examining the hidden health risks associated with Neonicotinoid Insecticides, the world's most widely used class of pesticides. Neonics are used extensively in agriculture, leading to inevitable occupational and environmental contamination, including detectable levels in food and water. Since these chemicals are applied systemically, they are absorbed throughout the plant tissues, making them very difficult—if not impossible—to remove completely by washing produce. Recent systematic reviews analyzing 21 animal studies consistently show that neonic exposure negatively impacts male reproductive health. Specifically, studies reveal compromised sperm quality (count, motility, viability, morphology), damage to testicular tissue, hormonal disruption (lowered serum testosterone), and severe oxidative stress. These consistent findings, derived primarily from rodent models, constitute a clear and urgent public health concern, emphasizing the critical need for dedicated human epidemiological studies. Resources for this episode:  - https://pubmed.ncbi.nlm.nih.gov/41016496/ - https://ejchem.journals.ekb.eg/article_222251.html - https://pmc.ncbi.nlm.nih.gov/articles/PMC11329541/

📣 New Podcast! "Neonicotinoid Insecticides: The Unseen Threat to Male Fertility" on @Spreaker #clothianidin #dna #edc #exposure #fertility #genotoxicity #hormones #imidacloprid #insecticides #male #neonicotinoids #oxidative #pesticides #reproductive #sperm #stress #testosterone #thiacloprid

Specific alterations of reactive species interactome markers reflect recovery after mild traumatic brain injury Recovery from mild traumatic brain injury (mTBI) is believed to be mediated by the secondary injury response with oxidative stress (OS) playing a cent…

🧠💥 New #clinical study out in FRBM
We show that #recovery after mild traumatic #brain injury isn’t just in your head — it’s in your #redox balance.
#Oxidative stress markers tell a surprising story about who heals, and how.
👉 Read the paper www.sciencedirect.com/science/arti...

The role of oral alpha-lipoic acid as an adjuvant antioxidant therapy in diabetic nephropathy among children and adolescents with type 1 diabetes: a randomized controlled trial Evaluate the oxidant-antioxidant balance and the efficacy of Alpha-lipoic acid (ALA) as an adjuvant therapy for diabetic nephropathy (DN) among indivi…

Egyptian researchers observe #lipoic #acid supplementation reduces #oxidative #stress in adolescents with type 1 #diabetes

www.sciencedirect.com/science/arti...

— randomized controlled trial
— 25 receive 300 mg/d ALA vs 25 placebo
— at 3 months, lower serum HbA1c & oxidation biomarkers

#science 🧪

Original post on healthrising.org

Is the Long COVID Field Missing a Major Opportunity? From viral persistence to complex immune studies to tissue sampling to assessing heavy-duty immune treatment trials and large treatment trials, ...

#Cardiovascular #Energy #Production #Exercise #Homepage […]

[Original post on healthrising.org]

Original post on healthrising.org

Is the Long COVID Field Missing a Major Opportunity? From viral persistence to complex immune studies, to tissue sampling, to assessing heavy-duty immune treatment trials and large treatment trials...

#Cardiovascular #Energy #Production #Exercise #Homepage […]

[Original post on healthrising.org]

inside front cover article in " #Environmental #Science: #Atmospheres" by @hh24.bsky.social et al. provides "A comparative study of methods for calculating the #oxidative potential (OP) of atmos. #particulate matter": pubs.rsc.org/en/content/a... / @tropos-de.bsky.social @unileipzig.bsky.social #UGA

DNA damage response pathway regulates Nrf2 in response to oxidative stress The DNA damage response pathway enhances antioxidant defense via Nrf2 regulation, uncovering a tissue-protective mechanism.

Chinese researchers show how #NRF2 cell repair pathway is triggered by #oxidative #stress via the #DNA damage response pathway

www.science.org/doi/10.1126/...

I recommend imagining your DNA as a 6-foot long stress sensor in every cell in your body!

🧪 #health #science #aging #longevity #autophagy

Here you have a crystal structure of the human BTB domain from a BACH1 homodimer (PDB code: 9GP5)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #molecularart #homodimer #bach1 #domain #cancer #oxidative #xray

🧪Assisted reproductive technologies rely on #sperm prep methods that can unintentionally damage sperm, lowering motility & increasing #oxidative DNA damage.

🔬 A new Aussie study tested BGP-15, a #noveltherapeutic, and found it boosted motility by 15% & reduced DNA damage.

Neurodegeneration, #Mutant #Oxidative Stress & Assumed "White Racist Traits - Erroneous":
The Data -Evidenced Side Effects of Low #Melanin Distribution in Human Brain Function - An Elementary #Neurobiological Perspective

theorionblogown.blogspot.com/2024/11/neur...

#neuroscience #university #PhD

Functionally redundant #Rho GTPases Cdc42 and #RacA regulate #aflatoxin synthesis and #pathogenicity in #Aspergillus flavus by controlling #morphogenesis, #oxidative balance and #energy metabolism
doi.org/10.1080/2150...
@tandfresearch.bsky.social

Get to know A G Jiménez
scholar.google.com/citations?us...
coauthor of

#Energetics and Oxidative Status: Seasonal Variation in Blood #Oxidative #Stress Metrics in Four Species of Small #Birds from a Cold Winter #Climate
doi.org/10.1093/iob/...

#ecology #ornithology #scientist #science

IOB
“In this study, we measured summer to winter differences in #oxidative balance in four species of resident passerine #birds…”

scholar.google.com/citations?us...
Et al and
Read
doi.org/10.1093/iob/...

#ornithology #biology #ecology #womeninstem #science

IOB's latest
Energetics and Oxidative Status: Seasonal Variation in Blood #Oxidative Stress Metrics in Four #Species of Small #Birds from a Cold Winter #Climate
A G Jiménez , C J Marolf , O R Gulseth , S K Anandan , D L Swanson (www.usdbiology.com/swanson/)

doi.org/10.1093/iob/...

#Science

🎙️Giving a #Webinar on #Tryptophan metabolism, #Oxidative stress 🧪, #Depression 😔, and #PTSD 🧠 Join the deep dive into #Mind- #Body biochemistry! 🌌 #MentalHealth #Neuroscience
www.eventbrite.com.au/e/may-2025-i...

Looks like an interesting #fungi read from @princetonupress.bsky.social & be sure to read our flagship journal ICB’s
Sclerotial #metamorphosis in filamentous fungi is induced by #oxidative stress
Christos D. Georgiou , Nikolaos Patsoukis , et al, doi.org/10.1093/icb/...

The latest issue of ACS Applied Materials & Interfaces (@ACS_AMI) is live! On the cover: “Investigating the #Antibacterial #Efficiency and Mechanism of Indole- and Naphthalimide-Mediated Benzimidazoles: #Membrane Damage, #Metabolic Inactivation, and #Oxidative #Stress against Bacillus subtilis“

Berries aren’t just tasty—they’re brain fuel. Blueberries and strawberries are rich in flavonoids that cross the blood-brain barrier to improve memory and reduce oxidative stress. They’ve even been linked to delayed brain aging and better cognitive performance over time.

Blueberries and strawberries are rich in flavonoids that cross the blood-brain barrier to improve #memory and reduce #oxidative stress.

Snack smart: aim for a handful of berries a few times a week.
Tiny fruit, big brain power. 🍓🫐

#brainhealth #nutrition

Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT)...

🚨BREAKING RESEARCH🚨 #CRISPR-edited mice🐭reveal new despair-based model for #Depression & #PTSD, highlighting #Oxidative & excitatory #Stress!🔥🏆“Monthly Featured Article” ISTRY IMR Press Landmark #MentalHealth #Neuroscience #GeneEditing doi.org/10.31083/FBL...

Rosemary Treatment of Alzheimer Disease The research team developed carnosic acid. Carnosic acid amplifies memory and betters disease related symptoms in mice.

Rosemary Treatment of Alzheimer Disease

www.linkedin.com/pulse/rosema...

#carnosicacid #diacca #antioxidant #stuartlipton #inflammation #antiinflammation #alzhiemersdisease #dementia #memory #learning #tauprotien #cognitive #oxidative #rosemary #death #scrippsresearch #scrippsresearchinstitute

Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT)...

🚨BREAKING RESEARCH🚨 #CRISPR-edited mice🐭reveal new despair-based model for #Depression & #PTSD, highlighting #Oxidative & excitatory #Stress!🔥🏆“Monthly Featured Article” ISTRY IMRPress Landmark @ChuaCyndi2020 #MentalHealth #Neuroscience #GeneEditing doi.org/10.31083/FBL...

Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT)...

🚨BREAKING RESEARCH🚨 #CRISPR-edited mice🐭reveal new despair-based model for #Depression & #PTSD, highlighting #Oxidative & excitatory #Stress!🔥🏆“Monthly Featured Article” ISTRY IMR Press Frontiers in Bioscience Landmark #MentalHealth #Neuroscience #GeneEditing doi.org/10.31083/FBL...

Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT)...

🚨BREAKING RESEARCH🚨 #CRISPR-edited mice🐭reveal new despair-based model for #Depression & #PTSD, highlighting #Oxidative & excitatory #Stress!🔥🏆“Monthly Featured Article” ISTRY IMR Press Frontiers in BioScience Landmark #MentalHealth #Neuroscience #GeneEditing doi.org/10.31083/FBL...

Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT)...

🚨BREAKING RESEARCH🚨 #CRISPR-edited mice🐭reveal new despair-based model for #Depression & #PTSD, highlighting #Oxidative & excitatory #Stress!🔥🏆“Monthly Featured Article” ISTRY IMR Press Frontiers in Bioscience Landmark #MentalHealth #Neuroscience #GeneEditing
doi.org/10.31083/FBL...

Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder Backgrounds: Memory and emotion are especially vulnerable to psychiatric disorders such as post-traumatic stress disorder (PTSD), which is linked to disruptions in serotonin (5-HT)...

🚨BREAKING!🚨🧠 #CRISPR/Cas9-edited mice reveal a new model for despair-based #Depression & #PTSD, exposing the role of #Oxidative & excitatory neurotoxic #Stress!💡🔬🔥Chosen as “Monthly Featured Article” by the International Society of #Tryptophan #Research!🏆
🔍Read now: doi.org/10.31083/FBL...

SciTech Chronicles. . . . . . . . .Feb 19th, 2025 Science is an attempt to remove our emotions and ego from reality. Vol II No 45 340 links Curated Lower antioxidant intake linked to incre...

SciTech Chronicles. . . . . . . . .Feb 19th, 2025

bit.ly/stc021925

#antioxidant #supplementation #oxidative #stress #crystal #synthetic #hexagonal #lonsdaleite #Robopalooza #telepresence #competition #Helelani #Coffee #Reishi #mycelia #Mycofluid #cognitive #anemia #lesions #slower

Discrete Hybrid Vanadium‐oxo Cluster as a Targeted Tool for Selective Protein Oxidative Modifications and Cleavage A hybrid vanadium-oxo cluster selectively binds to hen egg white lysozyme (HEWL) and facilitates localized oxidation in the vicinity of its binding site. These modifications occur under physiological...

We are proud to present our latest development! Our recent publication in #AngewandteChemie demonstrates the potential of a #DiscreteHybrid #Vanadium #OxoCluster to selectively induce #oxidative modifications in proteins under physiological conditions.
doi.org/10.1002/anie...