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U01.01.076 Vitamin B3 Test your knowledge of U01.01.076 Vitamin B3. Practice identifying the role of Niacin in ATP production, its use in treating hyperlipidemia, and the diagnostic hallmarks of Pellagra with this expert-curated MCQ set.

⚡ The Redox Regulator: Mastering Vitamin B3 (Niacin)! ⚡
#USMLEStep1 #MedEd #MedicalStudent #Biochemistry #VitaminB3 #Niacin #Step1Prep #HighYield #MedSchool #Pellagra #Metabolism #Tryptophan #USMLE #FutureDoctor #StudyGram #MedTwitter

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What Tryptophan Does To Your Brain

myopedia.org/tryptophan

#supplements #hormonesupport #aminoacids #brainhealth #sleep #tryptophan

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What Tryptophan Does To Your Brain

myopedia.org/tryptophan

#supplements #hormonesupport #aminoacids #brainhealth #sleep #tryptophan

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This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

Microbial metabolites can influence host physiology. This study shows that #microbial production of #indole from #bacterial #tryptophan catabolism enhances #lysosomal acidification & lipase activity in nematodes & mammalian hepatocytes @plosbiology.org 🧪 plos.io/3ZZAsaI

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This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

Microbial metabolites can influence host physiology. This study shows that #microbial production of #indole from #bacterial #tryptophan catabolism enhances #lysosomal acidification & lipase activity in nematodes & mammalian hepatocytes @plosbiology.org 🧪 plos.io/3ZZAsaI

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This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang

Microbial metabolites can influence host physiology. This study shows that #microbial production of #indole from #bacterial #tryptophan catabolism enhances #lysosomal acidification & lipase activity in nematodes & mammalian hepatocytes @plosbiology.org 🧪 plos.io/3ZZAsaI

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Depression of tryptophan may contribute to adverse effects of naproxen - Nature Communications Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) have been associated with adverse effects affecting both the cardiovascular and gastrointestinal systems. Here the authors show that NSAIDs lower plasma ...

#Tryptophan supplementation may attenuate #Naproxen adverse effects and widen its #TherapeuticIndex www.nature.com/articles/s41... @FitzGerald__Lab #Pharmacology #DrugMechanism #DrugSafety #TranslationalScience

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Genes are switched on & off to conserve energy. E.coli has 2 clever ways of controlling the genes needed to make #tryptophan. Learn more with our paper models!
Trp operon: buff.ly/oFPcRLQ
Trp attenuation: buff.ly/v6kwzf9

#EduSky #trpoperon #trpattenuation #microbiology #genetics #ecoli

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**Bold fact:** Normal behavior can hide toxic brain chemistry ⚡🧠🧪 KAT II KO rewires Trp–KYN pathways & boosts excitotoxic stress!🔬🚨 @mdpiopenaccess.bsky.social
#Neuroscience #Psychiatry #Neurobiology #Tryptophan #Kynurenine
👉 Read
www.mdpi.com/2073-4409/14...

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This isn’t #FolkMedicine—it’s precision #Nutrition!🍽️🔬 By steering #Tryptophan away from toxic routes ➡️ toward #Serotonin 🌈, #Phytochemicals may fuel the next generation of #Antidepressants! 💡🌍 @mdpiopenaccess.bsky.social #Neurobiology
doi.org/10.20944/pre...

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🪳💧Nutritional effects on the expression of cryptic pigmentation in freshwater isopods

vist.ly/4hpfm

#AminoAcids #DietaryResources #EcologicalStoichiometry #PhenotypicVariation #Pigmentation #Plasticity #Protein #Tryptophan

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You know what goes great with Thanksgiving Leftovers? An arsenal Win !! COYG

#CLEVELAND
#CHEARS
#TRYPTOPHAN

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Scientists found tryptophan, the ‘sleepy’ amino acid, in an asteroid. Here’s what it means An essential amino acid that is mistakenly believed to cause drowsiness after eating turkey has been found in an asteroid for the first time, giving scientists clues to the origin of life on Earth.

I find this interesting. First off, no, #Bennu is NOT a giant #spaceturkey despite them finding #tryptophan!

But that it has so many amino acids present does suggest that the building blocks of life were not that rare in the early solar system. That's pretty cool!

www.ctvnews.ca/sci-tech/art...

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Why you can’t blame your turkey’s tryptophan for your Thanksgiving food coma Every Thanksgiving, myths of the quasi-magical powers of tryptophan rise again. There’s the turkey/drowsiness myth: Eating lots of juicy turkey meat supposedly makes people feel tired because it contains...

Why you can’t blame your turkey’s tryptophan for your Thanksgiving food coma #Science #HealthandMedicine #Nutrition #Thanksgiving #FoodComa #Tryptophan

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NASA Finds Essential Tryptophan on Asteroid Bennu, Bolstering Life's Cosmic Start Scientists have announced the unprecedented discovery of Tryptophan, a complex essential amino acid, on samples from asteroid Bennu, bolstering theories that

NASA Finds Essential Tryptophan on Asteroid Bennu, Bolstering Life's Cosmic Start

#Bennu #NASA #originoflife #OSIRISREx #Tryptophan

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Thanksgiving turkey and tryptophan don't make you sleep The Thanksgiving turkey tryptophan myth suggests that turkey causes sleep is not supported by science. Blame the mashed potatos.

The Thanksgiving #turkey #tryptophan causes sleep myth is well-known. However, research shows turkey contains similar tryptophan levels as other meats, and it doesn’t impact sleep directly. Blame the carbohydrates.

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Huge Trypto-fan!*

*Contrary to popular belief, turkey does not contain significantly more tryptophan than other common meats, and it isn't what causes your food coma!

Huge Trypto-fan!* *Contrary to popular belief, turkey does not contain significantly more tryptophan than other common meats, and it isn't what causes your food coma!

It's time for my annual reminder that turkey does NOT contain more #tryptophan than other meats, and the molecule is not the cause of your food coma!

Nevertheless, I hope this #science pun is enough to drive you off your screens for some well-deserved relaxation.

Happy Thanksgiving!

🧪 #SciComm

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#Thanksgiving #Tryptophan #Turkey

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Regarding that #adage, “ #write what you know…” If I followed that strictly today, my #sequel would be a sleepy tale about a yawning #writer blearing at a cursor and sipping cold #tea. ☕️
#WritingCommunity
Pre- #Thanksgiving
#Turkey #Tryptophan #BrainDrain 🫩

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Thanksgiving turkey and tryptophan don't make you sleep The Thanksgiving turkey tryptophan myth suggests that turkey causes sleep is not supported by science. Blame the mashed potatos.

The Thanksgiving #turkey #tryptophan causes sleep myth is well-known. However, research shows turkey contains similar tryptophan levels as other meats, and it doesn’t impact sleep directly. Blame the carbohydrates. www.skepticalraptor.com/skepticalrap...

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Conventional meds only partly work!😔💊 Our review uncovers how #Tryptophan metabolism—the brain’s “Serotonin fuel—gets hijacked by #Stress & #Inflammation! 🔥🧬 @mdpiopenaccess.bsky.social #BrainHealth #MentalHealth
www.preprints.org/manuscript/2...

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🔥 #Microglia🧠 aren’t passive—they control #Neuroinflammation 🧯, #Mood 💭, and #Cognition 🧩! We mapped their tango💃with #Tryptophan #Metabolism🧬 @mdpiopenaccess.bsky.social #BrainHealth #Immunopsychiatry 📖 www.mdpi.com/1424-8247/18...

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Turkey Trippin' on Tryptophan! Huffin', Puffin', now bring on the stuffin'! 🦃😴
serenashirt.com/product/turk...
#Tryptophan #Thanksgiving #FunnyHoliday #Stuffing #Turkey

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🧠 What if progressive #MS isn’t just about myelin loss—but a hidden #Tryptophan trap? 😮🧩✨
#Neuroscience #MS #Biomarkers
👉 Discover the twist that could redefine MS treatment! 🔬📖💥 @mdpiopenaccess.bsky.social
#ResearchRevolution #ScienceTwitter #ShareScience
doi.org/10.3390/biom...

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#Sex 🔬, #Circadian clocks ⏰ & #Microbes 🦠 fine-tune #Tryptophan metabolism! We charted enzyme “hotspots” 🧩 at single-cell resolution 📊 → guiding next-gen @mdpiopenaccess.bsky.social #Therapies!
#PrecisionMedicine #Neurobiology
👉 www.mdpi.com/2227-9059/13...

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💔 #Despair isn’t just a feeling—it’s #Chemistry gone wild!🧬🧠Loss of KAT2 rewires #Tryptophan metabolism, bending #Serotonin & #Dopamine balance 🎢🔥 @mdpiopenaccess.bsky.social #MoodDisorders #Neurochemistry #BrainScience
👇 www.mdpi.com/2073-4409/14...

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The preponderance of evidence indicates that the KD is effective in targeting IESS.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #acidosis #infantileepilepticspasms #ketogenicdiet #microbiome #tryptophan

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🧠💥 #Depression, #PTSD & #Alzheimer’s may share a #Tryptophan storm!😱 KAT2 knockout mice reveal #Brain-region rewiring in #Trp#kynurenine metabolism🔄🔥 @mdpiopenaccess.bsky.social #Neuroscience #Depression #PTSD #Tryptophan #Kynurenine
👉
www.mdpi.com/2073-4409/14...

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🌋🌌 #OxidativeStress + #Tryptophan imbalance might hold the keys to #Despair! Dive into the full study!
Share it & spark change!🔥 #DepressionResearch #DrugDiscovery
👉 doi.org/10.31083/FBL... 📖✨

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🧠💥 #Depression, #PTSD & #Alzheimer’s may share a #Tryptophan storm!😱 KAT2 knockout mice reveal #Brain-region rewiring in #Trp#kynurenine metabolism🔄🔥 @mdpiopenaccess.bsky.social #Neuroscience #Depression #PTSD #Tryptophan #Kynurenine
👉
www.preprints.org/manuscript/2...

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