⚡ The Redox Regulator: Mastering Vitamin B3 (Niacin)! ⚡
#USMLEStep1 #MedEd #MedicalStudent #Biochemistry #VitaminB3 #Niacin #Step1Prep #HighYield #MedSchool #Pellagra #Metabolism #Tryptophan #USMLE #FutureDoctor #StudyGram #MedTwitter
What Tryptophan Does To Your Brain
myopedia.org/tryptophan
#supplements #hormonesupport #aminoacids #brainhealth #sleep #tryptophan
What Tryptophan Does To Your Brain
myopedia.org/tryptophan
#supplements #hormonesupport #aminoacids #brainhealth #sleep #tryptophan
This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang
Microbial metabolites can influence host physiology. This study shows that #microbial production of #indole from #bacterial #tryptophan catabolism enhances #lysosomal acidification & lipase activity in nematodes & mammalian hepatocytes @plosbiology.org 🧪 plos.io/3ZZAsaI
This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang
Microbial metabolites can influence host physiology. This study shows that #microbial production of #indole from #bacterial #tryptophan catabolism enhances #lysosomal acidification & lipase activity in nematodes & mammalian hepatocytes @plosbiology.org 🧪 plos.io/3ZZAsaI
This image depicts a nematode with fluorescently labeled bacteria in its intestine (left), illustrating microbial metabolic input. On the right, fluorescently marked epidermal lysosomes (top), intestinal lysosomes (middle), and lipid droplets (bottom) highlight the organelles engaged in lysosome-dependent lipid degradation. Together, the image visualizes a microbiota–lysosome axis through which bacterial tryptophan metabolism reprograms host lipid homeostasis. Image Credit: Kenan Zhang
Microbial metabolites can influence host physiology. This study shows that #microbial production of #indole from #bacterial #tryptophan catabolism enhances #lysosomal acidification & lipase activity in nematodes & mammalian hepatocytes @plosbiology.org 🧪 plos.io/3ZZAsaI
#Tryptophan supplementation may attenuate #Naproxen adverse effects and widen its #TherapeuticIndex www.nature.com/articles/s41... @FitzGerald__Lab #Pharmacology #DrugMechanism #DrugSafety #TranslationalScience
Genes are switched on & off to conserve energy. E.coli has 2 clever ways of controlling the genes needed to make #tryptophan. Learn more with our paper models!
Trp operon: buff.ly/oFPcRLQ
Trp attenuation: buff.ly/v6kwzf9
#EduSky #trpoperon #trpattenuation #microbiology #genetics #ecoli
**Bold fact:** Normal behavior can hide toxic brain chemistry ⚡🧠🧪 KAT II KO rewires Trp–KYN pathways & boosts excitotoxic stress!🔬🚨 @mdpiopenaccess.bsky.social
#Neuroscience #Psychiatry #Neurobiology #Tryptophan #Kynurenine
👉 Read
www.mdpi.com/2073-4409/14...
This isn’t #FolkMedicine—it’s precision #Nutrition!🍽️🔬 By steering #Tryptophan away from toxic routes ➡️ toward #Serotonin 🌈, #Phytochemicals may fuel the next generation of #Antidepressants! 💡🌍 @mdpiopenaccess.bsky.social #Neurobiology
doi.org/10.20944/pre...
🪳💧Nutritional effects on the expression of cryptic pigmentation in freshwater isopods
vist.ly/4hpfm
#AminoAcids #DietaryResources #EcologicalStoichiometry #PhenotypicVariation #Pigmentation #Plasticity #Protein #Tryptophan
You know what goes great with Thanksgiving Leftovers? An arsenal Win !! COYG
#CLEVELAND
#CHEARS
#TRYPTOPHAN
I find this interesting. First off, no, #Bennu is NOT a giant #spaceturkey despite them finding #tryptophan!
But that it has so many amino acids present does suggest that the building blocks of life were not that rare in the early solar system. That's pretty cool!
www.ctvnews.ca/sci-tech/art...
Why you can’t blame your turkey’s tryptophan for your Thanksgiving food coma #Science #HealthandMedicine #Nutrition #Thanksgiving #FoodComa #Tryptophan
NASA Finds Essential Tryptophan on Asteroid Bennu, Bolstering Life's Cosmic Start
#Bennu #NASA #originoflife #OSIRISREx #Tryptophan
The Thanksgiving #turkey #tryptophan causes sleep myth is well-known. However, research shows turkey contains similar tryptophan levels as other meats, and it doesn’t impact sleep directly. Blame the carbohydrates.
Huge Trypto-fan!* *Contrary to popular belief, turkey does not contain significantly more tryptophan than other common meats, and it isn't what causes your food coma!
It's time for my annual reminder that turkey does NOT contain more #tryptophan than other meats, and the molecule is not the cause of your food coma!
Nevertheless, I hope this #science pun is enough to drive you off your screens for some well-deserved relaxation.
Happy Thanksgiving!
🧪 #SciComm
Regarding that #adage, “ #write what you know…” If I followed that strictly today, my #sequel would be a sleepy tale about a yawning #writer blearing at a cursor and sipping cold #tea. ☕️
#WritingCommunity
Pre- #Thanksgiving
#Turkey #Tryptophan #BrainDrain
The Thanksgiving #turkey #tryptophan causes sleep myth is well-known. However, research shows turkey contains similar tryptophan levels as other meats, and it doesn’t impact sleep directly. Blame the carbohydrates. www.skepticalraptor.com/skepticalrap...
Conventional meds only partly work!😔💊 Our review uncovers how #Tryptophan metabolism—the brain’s “Serotonin fuel—gets hijacked by #Stress & #Inflammation! 🔥🧬 @mdpiopenaccess.bsky.social #BrainHealth #MentalHealth
www.preprints.org/manuscript/2...
🔥 #Microglia🧠 aren’t passive—they control #Neuroinflammation 🧯, #Mood 💭, and #Cognition 🧩! We mapped their tango💃with #Tryptophan #Metabolism🧬 @mdpiopenaccess.bsky.social #BrainHealth #Immunopsychiatry 📖 www.mdpi.com/1424-8247/18...
Turkey Trippin' on Tryptophan! Huffin', Puffin', now bring on the stuffin'! 🦃😴
serenashirt.com/product/turk...
#Tryptophan #Thanksgiving #FunnyHoliday #Stuffing #Turkey
🧠 What if progressive #MS isn’t just about myelin loss—but a hidden #Tryptophan trap? 😮🧩✨
#Neuroscience #MS #Biomarkers
👉 Discover the twist that could redefine MS treatment! 🔬📖💥 @mdpiopenaccess.bsky.social
#ResearchRevolution #ScienceTwitter #ShareScience
doi.org/10.3390/biom...
#Sex 🔬, #Circadian clocks ⏰ & #Microbes 🦠 fine-tune #Tryptophan metabolism! We charted enzyme “hotspots” 🧩 at single-cell resolution 📊 → guiding next-gen @mdpiopenaccess.bsky.social #Therapies!
#PrecisionMedicine #Neurobiology
👉 www.mdpi.com/2227-9059/13...
💔 #Despair isn’t just a feeling—it’s #Chemistry gone wild!🧬🧠Loss of KAT2 rewires #Tryptophan metabolism, bending #Serotonin & #Dopamine balance 🎢🔥 @mdpiopenaccess.bsky.social #MoodDisorders #Neurochemistry #BrainScience
👇 www.mdpi.com/2073-4409/14...
The preponderance of evidence indicates that the KD is effective in targeting IESS.
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #acidosis #infantileepilepticspasms #ketogenicdiet #microbiome #tryptophan
🧠💥 #Depression, #PTSD & #Alzheimer’s may share a #Tryptophan storm!😱 KAT2 knockout mice reveal #Brain-region rewiring in #Trp– #kynurenine metabolism🔄🔥 @mdpiopenaccess.bsky.social #Neuroscience #Depression #PTSD #Tryptophan #Kynurenine
👉
www.mdpi.com/2073-4409/14...
🌋🌌 #OxidativeStress + #Tryptophan imbalance might hold the keys to #Despair! Dive into the full study!
Share it & spark change!🔥 #DepressionResearch #DrugDiscovery
👉 doi.org/10.31083/FBL... 📖✨
🧠💥 #Depression, #PTSD & #Alzheimer’s may share a #Tryptophan storm!😱 KAT2 knockout mice reveal #Brain-region rewiring in #Trp– #kynurenine metabolism🔄🔥 @mdpiopenaccess.bsky.social #Neuroscience #Depression #PTSD #Tryptophan #Kynurenine
👉
www.preprints.org/manuscript/2...