Advanced lipidomic techniques for high-throughput profiling of complex sphingolipids in plant tissues - Journal of Plant Research Journal of Plant Research - Sphingolipids are essential membrane components that regulate various cellular functions by forming ordered domains. The structural core of sphingolipids comprises a...

“Advanced lipidomic techniques for high-throughput profiling of complex sphingolipids in plant tissues.” Ishikawa #Sphingolipid #Lipidome #OpenAccess link.springer.com/article/10.1...

Researchers used #PF543 (MedChemExpress) to interrogate the role of #sphingolipid metabolism in driving tumor cell survival. By inhibiting S1P production, PF543 abolished the survival advantage conferred by 3LS-positive plasma, confirming the central role of the ceramide-S1P axis in this phenotype.

#Cholesterol depletion activates #trafficking-coupled #sphingolipid synthesis. New study from Yeongho Kim, Jan Parolek, and Christopher G. Burd @yalecellbiology.bsky.social: rupress.org/jcb/article/...

#Membrane #lipid #Biochemistry

Plasma Metabonomics of Human Adenovirus-infected Patients with Pneumonia and Upper Respiratory Tract Infection

Scientists reveal distinct metabolite profiles in human #Adenovirus7 infection, showing altered #LipidMetabolism—especially #sphingolipid pathways—distinguishes #pneumonia from URTI and may offer an intervention target for #HAdV treatment.
Read: doi.org/10.1007/s115...

Peters, @sarawickstrom.bsky.social et al. show that #sphingolipid #metabolism orchestrates establishment of the hair follicle #StemCell compartment. rupress.org/jcb/article/...

📕 From The Year In Cell Biology: rupress.org/jcb/collecti...
#CellBio2025

Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes Protein palmitoylation and sphingolipid metabolism control lytic granule release in cytotoxic lymphocytes via membrane targeting of SNAP23.

Recently in #Science #Immunology: Kalinichenko, Huemer, @boztugk.bsky.social, & colleagues report than #sphingolipid #metabolism & protein #palmitoylation play critical roles in the killing of target cells by #cytotoxic #lymphocytes!

🎉 🌟Tamir Dingjan (Weizmann Institute of Science) won a FEBS Letters #PosterPrize at the FEBS Special Meeting on #Sphingolipid Biology in Varna, Bulgaria!

👏👏👏Congratulations, Tamir! 🎖️🎉

@slbiology.bsky.social‬

🏅🎉We congratulate 🌟Yaiza Varela Fernandez🌟 @ehu.eus, winner of the FEBS Letters #PosterPrize at the FEBS Special Meeting on #Sphingolipid Biology in Varna, Bulgaria! 👏👏👏🎉🎉

@slbiology.bsky.social

Spatial lipidomics reveals sphingolipid metabolism as anti-fibrotic target in the liver Steatotic liver disease (SLD), which encompasses various causes of fat accumulation in the liver, is a major cause of liver fibrosis. Understanding th…

Excited to share our latest study in Metabolism, exploring how dysregulated #sphingolipid #metabolism contributes to #liver #fibrosis using #spatial #lipidomics! A huge thank you to @gruevska.bsky.social and all the collaborators who made this possible!

www.metabolismjournal.com/article/S002...

eyes & #sphingolipid pathways are always interesting

#PaulKornerSeminar speaker Laura Choong @phenylauraline: ‘By generating new isoform-specific inhibitors of #ceramidesynthase , we may gain fundamental understanding of #sphingolipid and #ceramide biology.'
#CardioTwitter #ScienceTwitter #WomeninScience

#PaulKornerSeminar speaker Laura Choong @phenylauraline: ‘By generating new isoform-specific inhibitors of #ceramidesynthase , we may gain fundamental understanding of #sphingolipid and #ceramide biology.'
#CardioTwitter #ScienceTwitter #WomeninScience